Türkiye'de Hava Kirliliği Parametrelerinin Kardiyovasküler Mortalite Üzerine Etkisi

Yıl 2026, Cilt: 15 Sayı: 1 , 17 - 23 , 30.03.2026

Gürkan İmre

https://doi.org/10.46810/tdfd.1726926

https://izlik.org/JA42NE49FC

Öz

Bu ekolojik çalışmada amaç, Türkiye'de 81 ilin 2022 ve 2023 yılları arasında Partikül molekülü 10(PM10) ve Sülfür dioksit(SO₂) düzeylerindeki değişimin kardiyovasküler hastalıklara (CVD) bağlı ölüm hızları üzerindeki etkisini değerlendirmektir. Kardiyovasküler hastalıklara(CVD) bağlı ölüm hızları Türkiye İstatistik Kurumu’ndan(TUİK), PM10 ve SO₂ değerleri Çevre, Şehircilik ve İklim Değişikliği Bakanlığı verilerinden elde edildi. Veriler SPSS 25.0 ile analiz edildi; dağılım normalliği skewness, kurtosis ve q-q plot ile değerlendirildi; değişkenler arası ilişki Spearman korelasyon testi ile incelendi. Etkili değişkenleri belirlemek amacıyla çoklu doğrusal regresyon analizi uygulandı. Bulgularda PM10 ile CVD mortalite arasında zayıf fakat anlamlı bir pozitif ilişki saptandı (r=0.250, p=0.024). Regresyon analizinde PM10’nın kardiyovasküler mortalite hızı üzerinde anlamlı ve bağımsız etkisi olduğu görüldü (β=0.367, p<0.001). SO₂ değişkeni ile anlamlı bir ilişki bulunmadı. Sonuç olarak Türkiye’de 2022–2023 yılları arasında PM10 seviyelerindeki artışın, dolaşım sistemi hastalıklarına bağlı ölüm oranlarında artışla pozitif yönde ilişkili olduğu gösterilmiştir. Bu bulgu, hava kirliliği kontrol stratejilerinin halk sağlığı üzerindeki önemini bir kez daha ortaya koymaktadır

Anahtar Kelimeler

Hava kirliliği , PM10 , SO₂ , Kardiyovasküler mortalite

Effect of Air Pollution Parameters on Cardiovascular Mortality in Türkiye

https://izlik.org/JA42NE49FC

Öz

The aim of this study is to evaluate the effects of changes in particulate matterr 10 (PM10) and sulfur dioxide (SO₂) levels on mortality rates due to cardiovascular diseases (CVD) in 81 provinces in Türkiye between 2022 and 2023. Cardiovascular disease (CVD) mortality rates were obtained from the Turkish Statistical Institute (TUIK), and PM10 and SO₂ values were obtained from the Ministry of Environment, Urbanization, and Climate Change. Data were analyzed with SPSS 25.0; distribution normality was evaluated with skewness, kurtosis, and q-q plot; and the relationship between variables was examined with the Spearman correlation test. Multiple linear regression analysis was applied to determine the effective variables. In the findings, a weak but significant positive relationship was found between PM10 and CVD mortality(r=0.250, p=0.024). In the regression analysis, PM10 was found to have a significant and independent effect on cardiovascular mortality rate (β=0.367, p<0.001). No significant relationship was found with the SO₂ variable. As a result, it was shown that the increase in PM10 levels in Turkey between 2022 and 2023 is positively associated with the increase in mortality rates due to circulatory system diseases. This finding once again reveals the importance of air pollution control strategies on public health.

Anahtar Kelimeler

Air pollution , PM10 , SO₂ , Cardiovascular mortality

Etik Beyan

Çalışma için Etik Kurul Belgesine İhtiyaç Yoktur

Kaynakça

• Mensah GA, Fuster V, Murray CJL, Roth GA; Global Burden of Cardiovascular Diseases and Risks Collaborators. Global Burden of Cardiovascular Diseases and Risks, 1990-2022. J Am Coll Cardiol. 2023;82(25):2350-2473. doi:10.1016/j.jacc.2023.11.007
• WHO global air quality guidelines: Particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. Geneva: World Health Organization; 2021
• Mohammadi Dashtaki N, Fararouei M, Mirahmadizadeh A, Hoseini M. Association between exposure to air pollutants and cardiovascular mortality in Iran: a case-crossover study. Sci Rep. 2025;15(1):18762. Published 2025 May 28. doi:10.1038/s41598-025-04126-w
• Adebayo-Ojo TC, Wichmann J, Arowosegbe OO, Probst-Hensch N, Schindler C, Künzli N. Short-Term Effects of PM10, NO2, SO2 and O3 on Cardio-Respiratory Mortality in Cape Town, South Africa, 2006-2015. Int J Environ Res Public Health. 2022;19(13):8078. Published 2022 Jun 30. doi:10.3390/ijerph19138078
• Polichetti G, Cocco S, Spinali A, Trimarco V, Nunziata A. Effects of particulate matter (PM(10), PM(2.5) and PM(1)) on the cardiovascular system. Toxicology. 2009;261(1-2):1-8. doi:10.1016/j.tox.2009.04.035
• Chen TM, Gokhale J, Shofer S, Kuschner WG. Outdoor air pollution: nitrogen dioxide, sulfur dioxide, and carbon monoxide health effects. Am J Med Sci. 2007;333(4):249-256. doi:10.1097/MAJ.0b013e31803b900f
• Lawal AO. Air particulate matter induced oxidative stress and inflammation in cardiovascular disease and atherosclerosis: The role of Nrf2 and AhR-mediated pathways. Toxicol Lett. 2017;270:88-95. doi:10.1016/j.toxlet.2017.01.017
• Díaz-Chirón L, Negral L, Megido L, Suárez-Peña B, Domínguez-Rodríguez A, Rodríguez S. et al. Relationship Between Exposure to Sulphur Dioxide Air Pollution, White Cell Inflammatory Biomarkers and Enzymatic Infarct Size in Patients With ST-segment Elevation Acute Coronary Syndromes. Eur Cardiol. 2021;16:e50. Published 2021 Dec 7. doi:10.15420/ecr.2021.37
• Kim SY, Kim SH, Wee JH, Min C, Han SM, Kim S. et al. Short and long term exposure to air pollution increases the risk of ischemic heart disease. Sci Rep. 2021;11(1):5108. Published 2021 Mar 3. doi:10.1038/s41598-021-84587-x
• TÜİK. (2023). Ölüm ve Ölüm Nedeni İstatistikleri, 2022. Türkiye İstatistik Kurumu Haber Bülteni, 49679. Erişim Adresi: https://data.tuik.gov.tr/Bulten/Index?p=Olum-ve-Olum-Nedeni-Istatistikleri-2022- 49679.
• ÇŞB (Çevre ve Şehircilik Bakanlığı), 2023. Ulusal Hava Kalite İzleme Ağı. http://sim.csb.gov.tr/STN/STN_Report/Station DataDownloadNew, (Erişim Tarihi: 10.01.2023)
• Urbanowicz T, Skotak K, Olasińska-Wiśniewska A, Filipiak KJ, Bratkowski J, Wyrwa M, , et al. Long-Term Exposure to PM10 Air Pollution Exaggerates Progression of Coronary Artery Disease. Atmosphere. 2024; 15(2):216. https://doi.org/10.3390/atmos15020216
• Luo M, Xie X, Wu J, Zhang L, Zheng X, Xie M. et al. Association of ambient PM10 and PM2.5 with coronary stenosis measured using selective coronary angiography. Ecotoxicol Environ Saf. Published online August 7, 2023. doi:10.1016/j.ecoenv.2023.115338
• Li W, Cao Y, Li R, Ma X, Chen J, Wu Z. et al. The spatial variation in the effects of air pollution on cardiovascular mortality in Beijing, China. J Expo Sci Environ Epidemiol. 2018;28(3):297-304. doi:10.1038/jes.2016.21
• Maleki H, Sorooshian A, Goudarzi G, Nikfal A, Baneshi MM. Temporal profile of PM10 and associated health effects in one of the most polluted cities of the world (Ahvaz, Iran) between 2009 and 2014. Aeolian Res. 2016;22:135-140. doi:10.1016/j.aeolia.2016.08.006
• Bayart N-E, Rumchev K, Reid CM, Nyadanu SD, Pereira G. Association between Short-Term Exposure to Ambient Air Pollution and Mortality from Cardiovascular Diseases in Ulaanbaatar, Mongolia. Atmosphere. 2024; 15(9):1110. https://doi.org/10.3390/atmos15091110
• Kahraman AC, Sivri N. Comparison of metropolitan cities for mortality rates attributed to ambient air pollution using the AirQ model. Environ Sci Pollut Res Int. 2022;29(28):43034-43047. doi:10.1007/s11356-021-18341-1
• Bodor K, Micheu MM, Keresztesi Á, Birsan M-V, Nita I-A, Bodor Z, et al. Effects of PM10 and Weather on Respiratory and Cardiovascular Diseases in the Ciuc Basin (Romanian Carpathians). Atmosphere. 2021; 12(2):289. https://doi.org/10.3390/atmos12020289
• Donaldson K, Stone V, Seaton A, MacNee W. Ambient particle inhalation and the cardiovascular system: potential mechanisms. Environ Health Perspect. 2001;109 Suppl 4(Suppl 4):523-527. doi:10.1289/ehp.01109s4523
• Madaudo C, Coppola G, Parlati ALM, Corrado E. Discovering Inflammation in Atherosclerosis: Insights from Pathogenic Pathways to Clinical Practice. Int J Mol Sci. 2024;25(11):6016. Published 2024 May 30. doi:10.3390/ijms25116016
• Wang L, Liu C, Meng X, Niu Y, Lin Z, Liu Y, et al. Associations between short-term exposure to ambient sulfur dioxide and increased cause-specific mortality in 272 Chinese cities. Environ Int. 2018;117:33-39. doi:10.1016/j.envint.2018.04.019
• Amancio CT, Nascimento LF. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil. Braz J Med Biol Res. 2012;45(11):1080-1085. doi:10.1590/s0100-879x2012007500131.
• Geravandi S, Goudarzi GR, Vousoghi Niri M, Mohammadi MJ, Saeidimehr S, Geravandi S. Estimate of cardiovascular and respiratory mortality related to sulfur dioxide pollutant in Ahvaz. Journal of environmental studies. 2015; 41(2),341-350. https://10.22059/JES.2015.54985