Soğuk Atmosferik Plazma (CAP): Cilt Hastalıkları için Non-İnvaziv ve Ağrısız Bir Tedavi

Yıl 2026, Cilt: 15 Sayı: 1 , 221 - 232 , 30.03.2026

Berat Çınar Acar , Zehranur Yüksekdağ , Hazer Yüksekdağ , Tuğba Şahin , Elif Açar

https://doi.org/10.46810/tdfd.1762393

https://izlik.org/JA56KM92SF

Öz

Soğuk Atmosferik Plazma (CAP), tıp, gıda işleme, tarım ve endüstri gibi geniş bir yelpazede çok yönlü uygulamalarıyla dikkat çeken çığır açıcı bir teknoloji olarak ortaya çıkmıştır. Bu kapsamlı inceleme, CAP’nin akne, atopik dermatit, rozasea, vitiligo, sedef hastalığı ve otoimmün cilt bozuklukları gibi geniş bir cilt hastalığı yelpazesini tedavi etmedeki terapötik potansiyelini sistematik olarak değerlendirmektedir. CAP’nin etkinliği, reaktif türlerin üretimi, maliyet etkinliği, çevresel sürdürülebilirlik ve cihaz taşınabilirliği gibi benzersiz özelliklerine bağlanmaktadır; bu özellikler, nitrojen, argon veya helyum gibi gazlar kullanılarak dielektrik bariyer deşarjı, korona deşarjı ve yüzer elektrot yöntemleri gibi tekniklerle desteklenmektedir.
2013'ten 2025'e kadar olan hakemli çalışmaları kapsayan kapsamlı bir analiz aracılığıyla, bu araştırma, CAP'nin dermatolojik uygulamalarda son derece etkili ve uyarlanabilir bir araç olduğunu vurgulamaktadır. Bulgular, CAP’nin patojenleri nötralize etme, inflamatuar ve otoimmün yanıtları modüle etme kapasitesini öne çıkararak, onu klinik dermatolojide umut verici bir yöntem olarak konumlandırmaktadır. Bu titiz ve kapsamlı derleme, CAP tedavi protokollerinin optimize edilmesi, uygulama sistemlerinin geliştirilmesi ve genişleyen biyomedikal ile disiplinlerarası alanlarda terapötik potansiyelinin tam anlamıyla araştırılması için gelecekteki çalışmalara duyulan kritik ihtiyacı vurgulamaktadır.

Anahtar Kelimeler

Soğuk Atmosferik Plazma (CAP) , cilt hastalığı , akne , atopik dermatit , sedef hastalığı , rozasea (gül hastalığı) , vitiligo

Proje Numarası

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Cold Atmospheric Plasma (CAP): A Non-Invasive and Painless Treatment for Skin Diseases

https://izlik.org/JA56KM92SF

Öz

Cold Atmospheric Plasma (CAP) has emerged as a groundbreaking technology, attracting substantial interest for its versatile applications across medicine, food processing, agriculture, and industry. This comprehensive review systematically evaluates CAP’s therapeutic potential in treating a wide range of skin diseases, including acne, atopic dermatitis, rosacea, vitiligo, psoriasis, and autoimmune skin disorders. The efficacy of CAP is attributed to its unique characteristics, including the generation of reactive species, cost-effectiveness, environmental sustainability, and device portability, facilitated by techniques such as dielectric barrier discharge, corona discharge, and floating electrode methods, utilizing gases like nitrogen, argon, or helium. Through an exhaustive analysis of peer-reviewed studies spanning 2013 to 2025, this research underscores CAP’s role as a highly effective and adaptable tool in dermatological applications. The findings highlight CAP’s capacity to neutralize pathogens, modulate inflammatory and autoimmune responses, establishing it as a promising modality in clinical dermatology. This rigorous and comprehensive review emphasizes the critical need for future research to optimize CAP treatment protocols, enhance delivery systems, and fully explore its therapeutic potential across expanding biomedical and interdisciplinary fields.

Anahtar Kelimeler

Cold Atmospheric Plasma (CAP) , skin disease , acne , atopic dermatitis , psoriasis , rosacea , vitiligo

Etik Beyan

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Destekleyen Kurum

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Proje Numarası

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Teşekkür

The authors would like to thank Gazi University Academic Writing Application and Research Center (Certificate Number: 29.04.2024/063).

Kaynakça

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