Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2020, , 92 - 102, 23.10.2020
https://doi.org/10.46810/tdfd.776424

Öz

Destekleyen Kurum

Presidency of the Council of Higher Education, Presidency of Turkey Strategy and Budget, coordinated by The Scientific Research Projects Coordination Unit of Bingöl University

Proje Numarası

Project Number: 2017K124000-BÜBAP and PİKOM-Arı.2019.012/ BÜ-THBKP-ARI

Teşekkür

The authors gratefully acknowledge the financial support from the Presidency of the Council of Higher Education, Presidency of Turkey Strategy and Budget, coordinated by The Scientific Research Projects Coordination Unit of Bingöl University (Project Number: 2017K124000-BÜBAP and PİKOM-Arı.2019.012/ BÜ-THBKP-ARI). The authors also thank Bingöl University, the Center of Research and Application Center for their contributions.

Kaynakça

  • [1] Pasupuleti VR, Sammugam L, Ramesh N, Gan SH. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative Medicine And Cellular Longevity. 2017;2017.
  • [2] Anjum IS, Ullah A, Khan AK, Attaullah M, Khan H, Ali H, et al. Saudi Journal of Biological Sciences Composition and functional properties of propolis ( bee glue ): A review. Saudi Journal of Biological Sciences. 2019; 26(7):1695-1703.
  • [3] Isla MI, Paredes-Guzman JF, Nieva-Moreno MI, Koo H, Park YK. Some chemical composition and biological activity of northern Argentine propolis. Journal of Agricultural Food Chemistry. 2005;53(4):1166–72.
  • [4] Sobočanec S, Šverko V, Balog T, Šarić A, Rusak G, Likić S, et al. Oxidant/antioxidant properties of Croatian native propolis. Journal of Agricultural Food Chemistry. 2006;54(21):8018–26.
  • [5] Kim YH, Chung HJ. The effects of Korean propolis against food-borne pathogens and transmission electron microscopic examination. New Biotechnology. 2011;28(6):713–8.
  • [6] Seibert JB, Bautista-Silva JP, Amparo TR, Petit A, Pervier P, Dos Santos Almeida JC, et al. Development of propolis nanoemulsion with antioxidant and antimicrobial activity for use as a potential natural preservative. Food Chemistry. 2019;287:61–7.
  • [7] Gülçin I, Bursal E, Şehitoĝlu MH, Bilsel M, Gören AC. Polyphenol contents and antioxidant activity of lyophilized aqueous extract of propolis from Erzurum, Turkey. Food and Chemical Toxicology. 2010;48(8–9):2227–38.
  • [8] Marcucci MC. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie. 1995;26(2):83–99.
  • [9] Ristivojević P, Dimkić I, Guzelmeric E, Trifković J, Knežević M, Berić T, Yesilada E, Milojković-Opsenica D, Stanković, S. (2018). Profiling of Turkish propolis subtypes: Comparative evaluation of their phytochemical compositions, antioxidant and antimicrobial activities. LWT-Food Science and Technology, 2018;95, 367-379.
  • [10] Kumazawa S, Hamasaka T, Nakayama T. Antioxidant activity of propolis of various geographic origins. Food Chemistry. 2004;84(3):329–39.
  • [11] Nagai T, Inoue R, Inoue H, Suzuki N. Preparation and antioxidant properties of water extract of propolis. Food Chemistry. 2003;80(1):29–33.
  • [12] Ramón-Sierra J, Peraza-López E, Rodríguez-Borges R, Yam-Puc A, Madera-Santana T, Ortiz-Vázquez E. Partial characterization of ethanolic extract of Melipona beecheii propolis and in vitro evaluation of its antifungal activity. Brazilian Journal of Pharmacognosy. 2019;29(3):319–24.
  • [13] de Albuquerque IL, Alves LA, Lemos TLG, Dorneles CA, de Morais MO. Constituents of the essential oil of brazilian green propolis from Brazil. J Essent Oil Res. 2008;20(5):414–5.
  • [14] Bankova V, Boudourova-Krasteva G, Popov S, Sforcin JM, Funari SRC. Seasonal variations in essential oil from brazilian propolis. Journal of Essential Oil Research. 1998;10(6):693–6.
  • [15] Kusumoto T, Miyamoto T, Higuchi R, Doi S, Sugimoto H, Yamada H. Isolation and structures of two new compounds from the essential oil of Brazilian propolis. Chemical Pharmaceutical Bulletin. 2001;49(9):1207–9.
  • [16] Ioshida MDM, Young MCM, Lago JHG. Chemical composition and antifungal activity of essential oil from brazilian propolis. Journal of Essent Oil-Bearing Plants. 2010;13(5):633–7.
  • [17] Oliveira AP, França HS, Kuster RM, Teixeira LA, Rocha LM. Chemical composition and antibacterial activity of Brazilian propolis essential oil. Journal of Venomous Animals and Toxins including Tropical Diseases. 2010;16(1):121-30.
  • [18] Basim E, Basim H, Özcan M. Antibacterial activities of Turkish pollen and propolis extracts against plant bacterial pathogens. Journal of Food Engineering. 2006;77(4):992–6.
  • [19] Mihai CM, Mârghitaş LA, Dezmirean DS, Chirilâ F, Moritz RFA, Schlüns H. Interactions among flavonoids of propolis affect antibacterial activity against the honeybee pathogen Paenibacillus larvae. Journal of Invertebrate Pathology. 2012;110(1):68–72.
  • [20] Koru O, Toksoy F, Acikel CH, Tunca YM, Baysallara M, Guclu AU, et al. In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens. Anaerobe. 2007;13:140–5.
  • [21] Garedew A, Schmolz E, Lamprecht I. Microcalorimetric and respirometric investigation of the effect of temperature on the antivarroa action of the natural bee product-propolis. Thermochim Acta. 2003;399(1–2):171–80.
  • [22] Melliou E, Stratis E, Chinou I. Volatile constituents of propolis from various regions of Greece - Antimicrobial activity. Food Chemistry. 2007;103(2):375–80.
  • [23] Sinott FA, Sena-Lopes Â, Leal KS, Thais de Oliveira Silva M, Cardoso de Freitas M, Quintana de Moura M, et al. Essential oil from Brazilian Red Propolis exhibits anthelmintic activity against larvae of Toxocara cati. Expperimental Parasitology. 2019;200:37–41.
  • [24] Ahn M, Kumazawa S, Usui Y, Nakamura J. Food Chemistry Antioxidant activity and constituents of propolis collected in various areas of China. 2007;101:1383–92.
  • [25] Hochheim S, Guedes A, Faccin-Galhardi L, Rechenchoski DZ, Nozawa C, Linhares RE, et al. Determination of phenolic profile by HPLC–ESI-MS/MS, antioxidant activity, in vitro cytotoxicity and anti-herpetic activity of propolis from the Brazilian native bee Melipona quadrifasciata. Brazilian Journal of Pharmacognosy. 2019;29(3):339–50.
  • [26] Erdoğan MK, Geçibesler İH, Behçet L. Chemical constituents, antioxidant, antiproliferative and apoptotic effects of a new endemic Boraginaceae species: Paracaryum bingoelianum. Results in Chemistry. 2020;2:100032.
  • [27] Gecibesler IH. Antioxidant Activity and Phenolic Profile of Turkish Celtis tournefortii. Chemistry of Natural Compounds. 2019;55(4):738–42.
  • [28] Gecibesler IH, Yaglıoglu AS, Gul F, Temirturk M, Demirtas I. Phytochemicals of Chrysophthalmum montanum (DC.) Boiss. Roots and Their Antiproliferative Activities Against HeLa and C6 Cell Lines. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 2019;89(1):145–54.
  • [29] Geçibesler IH, Kiliç Ö, Demirtas I. Appraisal of biological activities of crude extracts with subfractions and phytochemical content of endemic Nepeta nuda L. subsp. lydiae from Turkey. Progress in Nutrition. 2017;19(1):121–9.
  • [30] Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; (CLSI). 2018. M100–S28.
  • [31] Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine. 1999;26(9-10):1231-7.
  • [32] Gecibesler IH, Kocak A, Demirtas I (2016) Biological activities, phenolic profiles and essential oil components of Tanacetum cilicicum (BOISS.) GRIERSON. Nat Prod Res 30:2850–2855.
  • [33] Bhattacharjee B, Pal PK, Chattopadhyay A, Bandyopadhyay D (2020) Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: A mechanistic study. Life Sci 244:117324.
  • [34] Kusumah D, Wakui M, Murakami M, Xie X, Yukihito K, Maeda I (2020) Linoleic acid, α-linolenic acid, and monolinolenins as antibacterial substances in the heat-processed soybean fermented with Rhizopus oligosporus. Biosci Biotechnol Biochem 84:1285–1290.
  • [35] Gecibesler IH, Erdogan M (2019) A new nutraceutical resource from a rare native plant growing in Turkey and for its spectro-chemical and biological insights: Endemic Diplotaenia bingolensis (Apiaceae). Spectrochim Acta - Part A Mol Biomol Spectrosc 223:117358.
  • [36] Abdel-Raouf N, Al-Enazi NM, Al-Homaidan AA, Ibraheem IBM, Al-Othman MR, Hatamleh AA. Antibacterial β-amyrin isolated from Laurencia microcladia. Arabian Journal Chemistry. 2015;8(1):32–7.
  • [37] Monzote L, Cuesta-Rubio O, Fernandez MC, Hernandez IM, Fraga J, Pérez K, et al. In vitro antimicrobial assessment of Cuban propolis extracts. Memorios do Instituto Oswaldo Cruz. 2012;107(8):978–84. [38] Papachroni D, Graikou K, Kosalec I, Damianakos H, Ingram V, Chinou I. Phytochemical analysis and biological evaluation of selected african propolis samples from Cameroon and Congo. Natural Products Communications. 2015;10(1):67–70.
  • [39] Gargouri W, Osés SM, Fernández-Muiño MA, Sancho MT, Kechaou N. Evaluation of bioactive compounds and biological activities of Tunisian propolis. Food Science and Technology. LWT. 2019;111:328–36.
  • [40] Regueira Neto MS, Tintino SR, da Silva ARP, Costa M do S, Boligon AA, Matias EFF, et al. Seasonal variation of Brazilian red propolis: Antibacterial activity, synergistic effect and phytochemical screening. Food and Chemical Toxicology. 2017;107:572–80.
  • [41] Uzel A, Sorkun K, Önçaǧ Ö, Çoǧulu D, Gençay Ö, Salih B. Chemical compositions and antimicrobial activities of four different Anatolian propolis samples. Microbiol Research. 2005;160(2):189–95.
  • [42] Kalogeropoulos N, Konteles SJ, Troullidou E, Mourtzinos I, Karathanos VT. Chemical composition, antioxidant activity and antimicrobial properties of propolis extracts from Greece and Cyprus. Food Chemistry. 2009;116(2):452–61.
  • [43] Kubiliene L, Laugaliene V, Pavilonis A, Maruska A, Majiene D, Barcauskaite K, et al. Alternative preparation of propolis extracts: Comparison of their composition and biological activities. BMC Complementary and Alternative Medicine. 2015;15(1):1–7.
  • [44] Agüero MB, Svetaz L, Sánchez M, Luna L, Lima B, López ML, et al. Argentinean Andean propolis associated with the medicinal plant Larrea nitida Cav. (Zygophyllaceae). HPLC-MS and GC-MS characterization and antifungal activity. Food Chemical and Toxicology. 2011;49(9):1970–8.
  • [45] Mirzoeva OK, Grishanin RN, Calder PC. Antimicrobial action of propolis and some of its components: The effects on growth, membrane potential and motility of bacteria. Microbiological Research. 1997;152(3):239–46.
  • [46] Petruzzi L, Corbo MR, Campaniello D, Speranza B, Sinigaglia M, Bevilacqua A. Antifungal and antibacterial effect of propolis: A comparative hit for food-borne pseudomonas, enterobacteriaceae and fungi. Foods. 2020;9(5):559.
  • [47] Freires IA, Queiroz VCPP, Furletti VF, Ikegaki M, de Alencar SM, Duarte MCT, et al. Chemical composition and antifungal potential of Brazilian propolis against Candida spp. Journal de mycologie medicale. 2016;26(2):122–32.
  • [48] Y Yang S, Peng L, Cheng Y, Chen F, Pan S. Control of citrus green and blue molds by Chinese propolis. Food Science and Biotechnology. 2010;19(5):1303–8.
  • [49] Gulcin İ. Antioxidants and antioxidant methods: an updated overview. Archives of Toxicology. 2020;94:651–715.
  • [50] Ozdal T, Ceylan FD, Eroglu N, Kaplan M, Olgun EO, Capanoglu E. Investigation of antioxidant capacity, bioaccessibility and LC-MS/MS phenolic profile of Turkish propolis. Food Research International. 2019;122:528–36.
  • [51] Pobiega K, Kraśniewska K, Gniewosz M. Application of propolis in antimicrobial and antioxidative protection of food quality – A review. Trends in Food Science& Technology. 2019;83:53–62.
  • [52] Atungulu Griffiths G, Toshitaka U, Fumihiko T, Daisuke H. Effect of vapors from fractionated samples of propolis on microbial and oxidation damage of rice during storage. Journal of Food Engineering. 2008;88(3):341–52.

Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi

Yıl 2020, , 92 - 102, 23.10.2020
https://doi.org/10.46810/tdfd.776424

Öz

Çalışmada Bingöl Propolis izolatlarını biyolojik aktivitesi ve kimyasal bileşimi araştırılmıştır. Propolisin etanol izolatı (Eİ), hekzan izolatı (Hİ) ve uçucu yağ izolatı (UYİ) ham propolisten hazırlanmıştır. İzolatların lipofilik ve uçucu organik bileşenleri Gaz Kromatografisi- Kütle Spektrometresi (GC-MS) ile analiz edilmiştir. Bingöl Propolis izolatları Staphylococcus aureus (ATCC 25923), Bacillus cereus (NRRL-B-3711) Escherichia coli (ATCC 25922), Salmonella enterica subsp. enterica serovar Typhimurium (ATCC 14028) referans patojen bakteri suşlarına karşı antimikrobiyal aktivite gösterirken, test edilen tüm propolis izolatlarına en duyarlı bakteri B. Cereus olduğu gözlenmiştir. Eİ izolatının diğer izolatlara kıyasla en yüksek antimikrobiyal ve antioksidan aktivite gösterdiği belirlenmiştir. Bingöl propolisinin lipofilik ve uçucu yağ izolatlarında biyoaktif bileşen varlığının, propolisin biyolojik aktivitesine katkıda bulunduğu değerlendirilmiştir. Çalışma kapsamında elde edilen Bingöl propolisi (Eİ ve UYİ) izolatlarının gıda sistemlerinde doğal koruyucular olarak kullanılabilme potansiyeline sahip olduğu belirlenmiştir.

Proje Numarası

Project Number: 2017K124000-BÜBAP and PİKOM-Arı.2019.012/ BÜ-THBKP-ARI

Kaynakça

  • [1] Pasupuleti VR, Sammugam L, Ramesh N, Gan SH. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative Medicine And Cellular Longevity. 2017;2017.
  • [2] Anjum IS, Ullah A, Khan AK, Attaullah M, Khan H, Ali H, et al. Saudi Journal of Biological Sciences Composition and functional properties of propolis ( bee glue ): A review. Saudi Journal of Biological Sciences. 2019; 26(7):1695-1703.
  • [3] Isla MI, Paredes-Guzman JF, Nieva-Moreno MI, Koo H, Park YK. Some chemical composition and biological activity of northern Argentine propolis. Journal of Agricultural Food Chemistry. 2005;53(4):1166–72.
  • [4] Sobočanec S, Šverko V, Balog T, Šarić A, Rusak G, Likić S, et al. Oxidant/antioxidant properties of Croatian native propolis. Journal of Agricultural Food Chemistry. 2006;54(21):8018–26.
  • [5] Kim YH, Chung HJ. The effects of Korean propolis against food-borne pathogens and transmission electron microscopic examination. New Biotechnology. 2011;28(6):713–8.
  • [6] Seibert JB, Bautista-Silva JP, Amparo TR, Petit A, Pervier P, Dos Santos Almeida JC, et al. Development of propolis nanoemulsion with antioxidant and antimicrobial activity for use as a potential natural preservative. Food Chemistry. 2019;287:61–7.
  • [7] Gülçin I, Bursal E, Şehitoĝlu MH, Bilsel M, Gören AC. Polyphenol contents and antioxidant activity of lyophilized aqueous extract of propolis from Erzurum, Turkey. Food and Chemical Toxicology. 2010;48(8–9):2227–38.
  • [8] Marcucci MC. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie. 1995;26(2):83–99.
  • [9] Ristivojević P, Dimkić I, Guzelmeric E, Trifković J, Knežević M, Berić T, Yesilada E, Milojković-Opsenica D, Stanković, S. (2018). Profiling of Turkish propolis subtypes: Comparative evaluation of their phytochemical compositions, antioxidant and antimicrobial activities. LWT-Food Science and Technology, 2018;95, 367-379.
  • [10] Kumazawa S, Hamasaka T, Nakayama T. Antioxidant activity of propolis of various geographic origins. Food Chemistry. 2004;84(3):329–39.
  • [11] Nagai T, Inoue R, Inoue H, Suzuki N. Preparation and antioxidant properties of water extract of propolis. Food Chemistry. 2003;80(1):29–33.
  • [12] Ramón-Sierra J, Peraza-López E, Rodríguez-Borges R, Yam-Puc A, Madera-Santana T, Ortiz-Vázquez E. Partial characterization of ethanolic extract of Melipona beecheii propolis and in vitro evaluation of its antifungal activity. Brazilian Journal of Pharmacognosy. 2019;29(3):319–24.
  • [13] de Albuquerque IL, Alves LA, Lemos TLG, Dorneles CA, de Morais MO. Constituents of the essential oil of brazilian green propolis from Brazil. J Essent Oil Res. 2008;20(5):414–5.
  • [14] Bankova V, Boudourova-Krasteva G, Popov S, Sforcin JM, Funari SRC. Seasonal variations in essential oil from brazilian propolis. Journal of Essential Oil Research. 1998;10(6):693–6.
  • [15] Kusumoto T, Miyamoto T, Higuchi R, Doi S, Sugimoto H, Yamada H. Isolation and structures of two new compounds from the essential oil of Brazilian propolis. Chemical Pharmaceutical Bulletin. 2001;49(9):1207–9.
  • [16] Ioshida MDM, Young MCM, Lago JHG. Chemical composition and antifungal activity of essential oil from brazilian propolis. Journal of Essent Oil-Bearing Plants. 2010;13(5):633–7.
  • [17] Oliveira AP, França HS, Kuster RM, Teixeira LA, Rocha LM. Chemical composition and antibacterial activity of Brazilian propolis essential oil. Journal of Venomous Animals and Toxins including Tropical Diseases. 2010;16(1):121-30.
  • [18] Basim E, Basim H, Özcan M. Antibacterial activities of Turkish pollen and propolis extracts against plant bacterial pathogens. Journal of Food Engineering. 2006;77(4):992–6.
  • [19] Mihai CM, Mârghitaş LA, Dezmirean DS, Chirilâ F, Moritz RFA, Schlüns H. Interactions among flavonoids of propolis affect antibacterial activity against the honeybee pathogen Paenibacillus larvae. Journal of Invertebrate Pathology. 2012;110(1):68–72.
  • [20] Koru O, Toksoy F, Acikel CH, Tunca YM, Baysallara M, Guclu AU, et al. In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens. Anaerobe. 2007;13:140–5.
  • [21] Garedew A, Schmolz E, Lamprecht I. Microcalorimetric and respirometric investigation of the effect of temperature on the antivarroa action of the natural bee product-propolis. Thermochim Acta. 2003;399(1–2):171–80.
  • [22] Melliou E, Stratis E, Chinou I. Volatile constituents of propolis from various regions of Greece - Antimicrobial activity. Food Chemistry. 2007;103(2):375–80.
  • [23] Sinott FA, Sena-Lopes Â, Leal KS, Thais de Oliveira Silva M, Cardoso de Freitas M, Quintana de Moura M, et al. Essential oil from Brazilian Red Propolis exhibits anthelmintic activity against larvae of Toxocara cati. Expperimental Parasitology. 2019;200:37–41.
  • [24] Ahn M, Kumazawa S, Usui Y, Nakamura J. Food Chemistry Antioxidant activity and constituents of propolis collected in various areas of China. 2007;101:1383–92.
  • [25] Hochheim S, Guedes A, Faccin-Galhardi L, Rechenchoski DZ, Nozawa C, Linhares RE, et al. Determination of phenolic profile by HPLC–ESI-MS/MS, antioxidant activity, in vitro cytotoxicity and anti-herpetic activity of propolis from the Brazilian native bee Melipona quadrifasciata. Brazilian Journal of Pharmacognosy. 2019;29(3):339–50.
  • [26] Erdoğan MK, Geçibesler İH, Behçet L. Chemical constituents, antioxidant, antiproliferative and apoptotic effects of a new endemic Boraginaceae species: Paracaryum bingoelianum. Results in Chemistry. 2020;2:100032.
  • [27] Gecibesler IH. Antioxidant Activity and Phenolic Profile of Turkish Celtis tournefortii. Chemistry of Natural Compounds. 2019;55(4):738–42.
  • [28] Gecibesler IH, Yaglıoglu AS, Gul F, Temirturk M, Demirtas I. Phytochemicals of Chrysophthalmum montanum (DC.) Boiss. Roots and Their Antiproliferative Activities Against HeLa and C6 Cell Lines. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 2019;89(1):145–54.
  • [29] Geçibesler IH, Kiliç Ö, Demirtas I. Appraisal of biological activities of crude extracts with subfractions and phytochemical content of endemic Nepeta nuda L. subsp. lydiae from Turkey. Progress in Nutrition. 2017;19(1):121–9.
  • [30] Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; (CLSI). 2018. M100–S28.
  • [31] Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine. 1999;26(9-10):1231-7.
  • [32] Gecibesler IH, Kocak A, Demirtas I (2016) Biological activities, phenolic profiles and essential oil components of Tanacetum cilicicum (BOISS.) GRIERSON. Nat Prod Res 30:2850–2855.
  • [33] Bhattacharjee B, Pal PK, Chattopadhyay A, Bandyopadhyay D (2020) Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: A mechanistic study. Life Sci 244:117324.
  • [34] Kusumah D, Wakui M, Murakami M, Xie X, Yukihito K, Maeda I (2020) Linoleic acid, α-linolenic acid, and monolinolenins as antibacterial substances in the heat-processed soybean fermented with Rhizopus oligosporus. Biosci Biotechnol Biochem 84:1285–1290.
  • [35] Gecibesler IH, Erdogan M (2019) A new nutraceutical resource from a rare native plant growing in Turkey and for its spectro-chemical and biological insights: Endemic Diplotaenia bingolensis (Apiaceae). Spectrochim Acta - Part A Mol Biomol Spectrosc 223:117358.
  • [36] Abdel-Raouf N, Al-Enazi NM, Al-Homaidan AA, Ibraheem IBM, Al-Othman MR, Hatamleh AA. Antibacterial β-amyrin isolated from Laurencia microcladia. Arabian Journal Chemistry. 2015;8(1):32–7.
  • [37] Monzote L, Cuesta-Rubio O, Fernandez MC, Hernandez IM, Fraga J, Pérez K, et al. In vitro antimicrobial assessment of Cuban propolis extracts. Memorios do Instituto Oswaldo Cruz. 2012;107(8):978–84. [38] Papachroni D, Graikou K, Kosalec I, Damianakos H, Ingram V, Chinou I. Phytochemical analysis and biological evaluation of selected african propolis samples from Cameroon and Congo. Natural Products Communications. 2015;10(1):67–70.
  • [39] Gargouri W, Osés SM, Fernández-Muiño MA, Sancho MT, Kechaou N. Evaluation of bioactive compounds and biological activities of Tunisian propolis. Food Science and Technology. LWT. 2019;111:328–36.
  • [40] Regueira Neto MS, Tintino SR, da Silva ARP, Costa M do S, Boligon AA, Matias EFF, et al. Seasonal variation of Brazilian red propolis: Antibacterial activity, synergistic effect and phytochemical screening. Food and Chemical Toxicology. 2017;107:572–80.
  • [41] Uzel A, Sorkun K, Önçaǧ Ö, Çoǧulu D, Gençay Ö, Salih B. Chemical compositions and antimicrobial activities of four different Anatolian propolis samples. Microbiol Research. 2005;160(2):189–95.
  • [42] Kalogeropoulos N, Konteles SJ, Troullidou E, Mourtzinos I, Karathanos VT. Chemical composition, antioxidant activity and antimicrobial properties of propolis extracts from Greece and Cyprus. Food Chemistry. 2009;116(2):452–61.
  • [43] Kubiliene L, Laugaliene V, Pavilonis A, Maruska A, Majiene D, Barcauskaite K, et al. Alternative preparation of propolis extracts: Comparison of their composition and biological activities. BMC Complementary and Alternative Medicine. 2015;15(1):1–7.
  • [44] Agüero MB, Svetaz L, Sánchez M, Luna L, Lima B, López ML, et al. Argentinean Andean propolis associated with the medicinal plant Larrea nitida Cav. (Zygophyllaceae). HPLC-MS and GC-MS characterization and antifungal activity. Food Chemical and Toxicology. 2011;49(9):1970–8.
  • [45] Mirzoeva OK, Grishanin RN, Calder PC. Antimicrobial action of propolis and some of its components: The effects on growth, membrane potential and motility of bacteria. Microbiological Research. 1997;152(3):239–46.
  • [46] Petruzzi L, Corbo MR, Campaniello D, Speranza B, Sinigaglia M, Bevilacqua A. Antifungal and antibacterial effect of propolis: A comparative hit for food-borne pseudomonas, enterobacteriaceae and fungi. Foods. 2020;9(5):559.
  • [47] Freires IA, Queiroz VCPP, Furletti VF, Ikegaki M, de Alencar SM, Duarte MCT, et al. Chemical composition and antifungal potential of Brazilian propolis against Candida spp. Journal de mycologie medicale. 2016;26(2):122–32.
  • [48] Y Yang S, Peng L, Cheng Y, Chen F, Pan S. Control of citrus green and blue molds by Chinese propolis. Food Science and Biotechnology. 2010;19(5):1303–8.
  • [49] Gulcin İ. Antioxidants and antioxidant methods: an updated overview. Archives of Toxicology. 2020;94:651–715.
  • [50] Ozdal T, Ceylan FD, Eroglu N, Kaplan M, Olgun EO, Capanoglu E. Investigation of antioxidant capacity, bioaccessibility and LC-MS/MS phenolic profile of Turkish propolis. Food Research International. 2019;122:528–36.
  • [51] Pobiega K, Kraśniewska K, Gniewosz M. Application of propolis in antimicrobial and antioxidative protection of food quality – A review. Trends in Food Science& Technology. 2019;83:53–62.
  • [52] Atungulu Griffiths G, Toshitaka U, Fumihiko T, Daisuke H. Effect of vapors from fractionated samples of propolis on microbial and oxidation damage of rice during storage. Journal of Food Engineering. 2008;88(3):341–52.
Toplam 51 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Mühendislik
Bölüm Makaleler
Yazarlar

Dılhun Keriman Arserim Uçar 0000-0001-8011-5059

İbrahim Halil Geçibesler 0000-0002-4473-2671

Mert Sudağıdan Bu kişi benim 0000-0002-3980-8344

İnan Dursun 0000-0003-1717-8166

Veysel Süzerer Bu kişi benim 0000-0001-5383-4613

Ramazan Solmaz 0000-0002-9295-1203

Proje Numarası Project Number: 2017K124000-BÜBAP and PİKOM-Arı.2019.012/ BÜ-THBKP-ARI
Yayımlanma Tarihi 23 Ekim 2020
Yayımlandığı Sayı Yıl 2020

Kaynak Göster

APA Arserim Uçar, D. K., Geçibesler, İ. H., Sudağıdan, M., Dursun, İ., vd. (2020). Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi. Türk Doğa Ve Fen Dergisi, 9(Özel Sayı), 92-102. https://doi.org/10.46810/tdfd.776424
AMA Arserim Uçar DK, Geçibesler İH, Sudağıdan M, Dursun İ, Süzerer V, Solmaz R. Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi. TDFD. Ekim 2020;9(Özel Sayı):92-102. doi:10.46810/tdfd.776424
Chicago Arserim Uçar, Dılhun Keriman, İbrahim Halil Geçibesler, Mert Sudağıdan, İnan Dursun, Veysel Süzerer, ve Ramazan Solmaz. “Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik Ve Uçucu Organik Bileşenlerinin Belierlenmesi”. Türk Doğa Ve Fen Dergisi 9, sy. Özel Sayı (Ekim 2020): 92-102. https://doi.org/10.46810/tdfd.776424.
EndNote Arserim Uçar DK, Geçibesler İH, Sudağıdan M, Dursun İ, Süzerer V, Solmaz R (01 Ekim 2020) Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi. Türk Doğa ve Fen Dergisi 9 Özel Sayı 92–102.
IEEE D. K. Arserim Uçar, İ. H. Geçibesler, M. Sudağıdan, İ. Dursun, V. Süzerer, ve R. Solmaz, “Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi”, TDFD, c. 9, sy. Özel Sayı, ss. 92–102, 2020, doi: 10.46810/tdfd.776424.
ISNAD Arserim Uçar, Dılhun Keriman vd. “Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik Ve Uçucu Organik Bileşenlerinin Belierlenmesi”. Türk Doğa ve Fen Dergisi 9/Özel Sayı (Ekim 2020), 92-102. https://doi.org/10.46810/tdfd.776424.
JAMA Arserim Uçar DK, Geçibesler İH, Sudağıdan M, Dursun İ, Süzerer V, Solmaz R. Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi. TDFD. 2020;9:92–102.
MLA Arserim Uçar, Dılhun Keriman vd. “Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik Ve Uçucu Organik Bileşenlerinin Belierlenmesi”. Türk Doğa Ve Fen Dergisi, c. 9, sy. Özel Sayı, 2020, ss. 92-102, doi:10.46810/tdfd.776424.
Vancouver Arserim Uçar DK, Geçibesler İH, Sudağıdan M, Dursun İ, Süzerer V, Solmaz R. Bingöl Propolis İzolatlarının Biyolojik Aktivitesinin, Lipofilik ve Uçucu Organik Bileşenlerinin Belierlenmesi. TDFD. 2020;9(Özel Sayı):92-102.