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Formulation and evaluation of peel-off gel mask with St. John's Wort oil and activated carbon from pine cone

Yıl 2025, Cilt: 14 Sayı: 3, 156 - 164, 26.09.2025
https://doi.org/10.46810/tdfd.1624013

Öz

Skin needs care to protect against environmental pollution. The facial skin can be protected such as cream, peel off mask and lotion facemask. This study aim is to develop the antibacterial peel-off mask gel containing St. John's Wort oil (Hypericum perforatum oil). This peel-off gel mask consists of ascorbic acid, polyvinyl alcohol (PVA, as preservative), polyethylene glycol (PEG), glycerine (as plasticizer), polysorbate (tween 20, as stabilizer), ethanol and distilled water with the addition of St. John's Wort Oil and active carbon. The peel-off physical properties (homogeneity, spreadability, viscosity, film-drying time), chemical properties (pH value, stability and antibacterial activity properties) were examined. Using of an active ingredient in peel off mask, it strengthens the role of peel off mask by opening the clogged pores. Activated carbon (AC) was added to this formulation as an active ingredient due to its adsorbent activity. In this present study, activated carbon was obtained from pine cone (PC). The specific surface area (SBET) of activated carbon was found to be 536.998 m²/g. The antimicrobial activity of the St. John's Wort oil was tested against Gram-negative bacteria (Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus) as well as one pathogenic fungus (Candida albicans, ATCC 10231). Disc diffusion method was used to study antimicrobial activity. The prepared peel of mask showed a good peeling feature without causing edema or irritation on the skin and that it can increase skin cleansing by removing the dirt in the skin pores.

Kaynakça

  • Ridwanto R, Lubis M, Syahputra R, Inriyani H. Utilisation of biopolymer combination as a material for making gel peel off mask. Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education. AISTSSE 18-19 October 2018, Medan, Indonesia.
  • Somwanshi S, Kudale K, Dolas R, Kotade K. Formulatıon and evaluatıon of cosmetıc herbal face pack for glowıng skın. International Journal of Pharmacy and Biological Sciences. 2018:8 (4):49-52. https://doi.org/ 10.7897/2277-4343.083199.
  • Rum I, Suherman H. Formulation and evaluation of peel-off gel mask from whole milk yogurt and seaweed (Eucheuma cottonii) as antioxidants sources. Pharmacy & Pharmacology International Journal. 2021;9(4):132‒135. https://doi.org/10.15406/ppij.2021.09.00338.
  • Kulkarnı S, Gupta D, Bhawsar S. Formulatıon and evaluatıon of actıvated charcoal peel off mask. International Journal of Pharmacy Research & Technology. 2019; 9 (2): 44-48. https://doi.org/10.31838/ijprt/09.02.06.
  • Beringhs A, Rosa J, Stulzer H, Budal R. Sonaglio D. Green clay and aloe vera peel-off facial masks: response surface methodology applied to the formulation design. AAPS Pharm Sci Tech. 2013;14(1):444-455. https://doi.org/10.1208/s12249-013-9930-8.
  • Budiman A, Aulifa D, Kusuma A, Kurniawan I, Sulastri A. Peel-off gel formulation from black mulberries (Morus nigra) extract as anti-acne mask. January National Journal of Physiology Pharmacy and Pharmacology. 2017; 7(10):987-994. https://doi.org/10.5455/njppp.2017.7.0413123052017.
  • Vieira R, Fernandes A, Kaneko T, Consiglieri V, Pinto C, Pereira C, et al. Physical and physicochemical stability evaluation of cosmetic formulations containing soybean extract fermented by Bifidobacterium animalis. Brazilian Journal of Pharmaceutical Science. 2009; 45(3):515-525.https://doi.org/10.1590/S1984-82502009000300018.
  • Iqbal M, Ashiq M. Adsorption of dyes from aqueous solutions on activated charcoal. Journal of Hazardous Materials B. 2007; 139: 57–66. https://doi.org/10.1016/j.jhazmat.2006.06.007.
  • Demirak A, Keskin F, Şahin Y, Kalemci V. Removal of ammonium from water by pine cone powder as biosorbent. Mugla Journal of Science and Technology. 2015; 1(1): 5-12. https://doi.org/10.22531/muglajsci.209992.
  • Gaudreault P. Activated Charcoal Revisited. Clinical Pediatric Emergency Medicine. 2005; 6(2) :76-80. https://doi.org/10.1016/j.cpem.2005.04.005.
  • Bhomick P, Supong A, Baruah M, Pongener C, Sinha D. Pine Cone biomass as an efficient precursor for the synthesis of activated biocarbon for adsorption of anionic dye from aqueous solution: Isotherm, kinetic, thermodynamic and regeneration studies. Sustainable Chemistry and Pharmacy. 2018; 10:41–49. https://doi.org/10.1016/j.scp.2018.09.001.
  • Bhat M, Yadav N, Hashmi S. Pinecone-derived porous activated carbon for high performance all-solid-state electrical double layer capacitors fabricated with flexible gel polymer electrolytes. Electrochimica Acta. 2019; 304:94-108. https://doi.org/10.1016/j.electacta.2019.02.092.
  • Eroglu E. Girgin S. A unique phenolic extraction method from olive oil macerate of Hypericum perforatum using DMSO: Assessment of in vitro anticancer activity, LC-MS/MS profile, total phenolic content and antioxidant capacity. South African Journal of Botany. 2021; 139: 6-11. https://doi.org/10.1016/j.sajb.2021.01.015.
  • Orhan I, Kartal M, Gülpinar A, Cos P, Matheeussen A, Maes L. et al. Assessment of antimicrobial and antiprotozoal activity of the olive oil macerate samples of Hypericum perforatum and their LC-DAD-MS analyses. Food Chemistry. 2013;138 (2–3):870-875. https://doi.org/10.1016/j.foodchem.2012.11.053.
  • Maisenbacher P, Kovar K. Analysis and stability of Hyperici oleum, Planta Med. 1992; 58(4): 351-354. https://doi.org/10.1055/s-2006-961483.
  • Isacchi B, Bergonzi M, Carnevali F, Esch S, Vincieri F, Bilia A. Analysis and stability of the constituents of St. John’s wort oils prepared with different methods. Journal of Pharmaceutical and Biomedical Analysis. 2007; 45: 756–761. https://doi.org/10.1016/j.jpba.2007.08.025.
  • Gîtea D, Şıpoş M, Mırcea T, Paşca B. The analysis of alcoholic extracts of hypericum species by: UVv/Vis spectrophotometry. Analele Universităţii din Oradea-Fascicula Biologie Tom. XVII / 1, 2010: 111-115.
  • Milosevic T, Solujıc S, Sukdolak S. In vitro study of ethanolic extract of Hypericum perforatum L. on growth and sporulation of some bacteria and fungi. Turkish Journal of Biology. 2007: 31: 237-241.
  • Eğri Ö, Erdemir N. Production of Hypericum perforatum oil-loaded membranes for wound dressing material and in vitro tests. Artıfıcıal Cells, Nanomedıcıne, And Bıotechnology. 2019; 47(1) :1404–1415. https://doi.org/10.1080/21691401.2019.1596933.
  • Zhang J, Feng C, Ge P, Wang Q, Liu Y, Xu H, Zhou X. High purity separation of hypericin from Hypericum perforatum L. Extract with macroporous resin column coupling preparative liquid chromatography. Process Biochemistry. 2021; 103: 107–113. https://doi.org/10.1016/j.procbio.2021.02.012.
  • Jarzębski M, Smułek W, Baranowska H, Masewicz L, Kobus-Cisowska J, Ligaj M, et al. Characterization of St. John’s wort (Hypericum perforatum L.) and the impact of filtration process on bioactive extracts incorporated into carbohydrate-based hydrogels. Food Hydrocolloids. 2020; 104: 105748. https://doi.org/10.1016/j.foodhyd.2020.105748.
  • Shimamori Y. Mitsunaka S, Yamashita H, Suzuki T, Kitao T, Kubori T, et al. Staphylococcal Phage in Combination with Staphylococcus epidermidis as a Potential Treatment for Staphylococcus aureus-Associated Atopic Dermatitis and Suppressor of Phage-Resistant Mutants. Viruses. 2021; 13 (7). https://dx.doi.org/10.3390/v13010007.
  • Magnifico I, Petronio G, Venditti N, Cutuli M, Pietrangelo L, Vergalito F, et al. Atopic dermatitis as a multifactorial skin disorder. Can the analysis of pathophysiological targets represent the winning therapeutic strategy. Pharmaceuticals. 2020; 13(411). https://doi.org/10.3390/ph13110411.
  • Lubbe J. Secondary infections in patients with atopic dermatitis. American Journal of Clinical Dermatology. 2003; 4 (9):641-654. https://doi.org/10.2165/00128071-200304090-00006.
  • Nowicka D, Chilicka K, Dziendziora-Urbinska I. Host-microbe interaction on the skin and its role in the pathogenesis and treatment of atopic dermatitis. Pathogens. 2022; 11 (71). https://doi.org/10.3390/pathogens11010071.
  • Lacour J. Skin microbiota and atopic dermatitis: toward new therapeutic options?. Annales de Dermatologie et de Vénéréologie. 2015;142(1):18-22. https://doi.org/10.1016/S0151-9638(15)30003-X.
  • Li K, Tian S, Jiang J, Wang J, Chen X, Yan F. Pine cone shells-based activated carbon used for CO2 adsorption. Journal of Materials Chemistry A. 2016;4(14):5223–5234. https://doi.org/10.1039/C5TA09908K.
  • Arsić I. Preparation and characterization of St. John’s Wort herb extracts using olive, sunflower and palm oils. Acta Facultatis Medicae Naissensis. 2016;33(2):119-126. https://doi.org/10.1515/afmnai-2016-0013.
  • Aydın G, Şirin N, Kekeçoğlu M, Türken T, Sipahi N., Göksu H. The use of natural preservative propolis and hypericum perforatum oil in herbal cream production. International Journal of Traditional and Complementary Medicine Research. 2021; 2 (1): 27 – 35. https://dergipark.org.tr/tr/pub/ijtcmr/issue/61352/807509.
  • Tanjung Y, Julıantı A, Isnayantı I, Ricsa A. Formulation and evaluatıon of peel off gel facıal mask from arabica coffee fruıt peel extract (coffea arabica L.). International Journal of Applied Pharmaceutics. 2021;13(4):148-151. https://doi.org/10.22159/ijap.2021.v13s4.43845
  • Bhalodia R, Shukla J. Antibacterial and antifungal activities from leaf extracts of cassia fistula l.: An ethnomedicinal plant. J. Adv. Pharm. Technol. Res. 2011; 2:104-109. https://doi.org/ 10.4103/2231-4040.82956.
  • Daoud A, Malika D, Bakari S, Hfaiedh N, Mnafgui K, Kadri A, et al. Assessment of polyphenol composition, antioxidant and antimicrobial properties of various extracts of date palm pollen (DPP) from two Tunisian cultivars. Arab. J. Chem. 2015;12(8) 3075-3086. https://doi.org/10.1016/j.arabjc.2015.07.014.
  • Ahmad I, Sheraz M, Ahmed S, Shaikh R, Vaid F, Khattak S, et al. Photostability and interaction of ascorbic acid in cream formulations. AAPS PharmSciTech. 2011;12(3):917. https://doi.org/ 10.1208/s12249-011-9659-1.
  • Sheraz M, Khan M, Ahmed S, Kazi S, Khattak S, Ahmad, I. Factors affecting formulation characteristics and stability of ascorbic acid in water-in-oil creams. International Journal of Cosmetic Science. 2014;36: 494–504. https://doi.org/10.1111/ics.12152.
  • Sarabandi D, Roudini G, Barahuie F. Activated carbon derived from pine cone as a framework for the preparation of n-heptadecane nanocomposite for thermal energy storage. Journal of Energy Storage. 2019; 24100795. https://doi.org/10.1016/j.est.2019.100795.
  • Assefi M, Davar F, Hadadzadeh H. Green synthesis of nanosilica by thermal decomposition of pine cones and pine needles. Advanced Powder Technology. 2015; 26: 1583–1589. https://doi.org/10.1016/j.apt.2015.09.004.
  • Zsirka B, Horvath E, Jarvas Z, Dallos A, Mako E, Kristof J. Structural and energetical characterization of exfoliated kaolinite surfaces. Appl. Clay Sci. 2016;124-125: 54-61. https://doi.org/10.1016/j.clay.2016.01.035.
  • Sajjad M, Sarwar R, Ali T, Khan L, Mahmood S. Cosmetic uses of activated charcoal. International Journal of Community Medicine and Public Health. 2021; 8: 4572-4574. https://dx.doi.org/10.18203/2394-6040.ijcmph20213569.
  • Orchard A, Vuuren S. Commercial essential oils as potential antimicrobials to treat skin diseases. Evidence-Based Complementary and Alternative Medicine. 2017;4517971: 92. https://doi.org/10.1155/2017/4517971.
  • Elgayyar M, Draughon F. A, Golden D. A, Mount J. R. Antimicrobial activity of essential oils from plants against selected pathogenic and saprophytic microorganisms. Journal of Food Protection. 2001; 64:1019–1024. https://doı: 10.4315/0362-028x-64.7.1019.
  • Burt S. Essential oils: their antibacterial properties and potential applications in foods-a review. Int. J. Food Microbiol. 2004;94: 223–253. https://doı:10.1016/j.ijfoodmicro.2004.03.022.
  • Badnore A, Sorde K, Datir K, Ananthanarayan L, Pratap A, Pandit A. Preparation of antibacterial peel-off facial mask formulation incorporating biosynthesized silver nanoparticles. Applied Nanoscience. 2019;9: 279–287. https://doi.org/10.1007/s13204-018-0934-2.
  • Rahmasari D, Ermawati D, Weka Nugraheni R, Ramadhaningtyas Putri D, Nur Pratiwi I. Design and development of peel-off mask gel formulation of citronella oil for acne vulgaris. In Proceedings of the 2nd Health Science International Conference (HSIC 2019), 157-163. ISBN: 978-989-758-462-6. https://doi.org/10.5220/0009126101570163.
  • Ali S, Yosipovitch G. Skin pH: From Basic Science to Basic Skin Care. Acta Derm Venereol. 2013; 93: 261–267. https://doi.org/10.2340/00015555-1531.
  • Hariyadi D, Isnaeni I, Sudarma S, Suciati S, Rosita N. Peel-off emulgel mask of Cocos nucifera L. extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827. Journal of Advanced Pharmaceutical Technology & Research, 2022;11 (4): 220-225. https://doi.org/10.4103/japtr.JAPTR_51_20from: https://www.fhi.no/nettpub/utbruddsveilederen/

Formulation and evaluation of peel-off gel mask with St. John's Wort oil and activated carbon from pine cone

Yıl 2025, Cilt: 14 Sayı: 3, 156 - 164, 26.09.2025
https://doi.org/10.46810/tdfd.1624013

Öz

Skin needs care to protect against environmental pollution. The facial skin can be protected such as cream, peel off mask and lotion facemask. This study aim is to develop the antibacterial peel-off mask gel containing St. John's Wort oil (Hypericum perforatum oil). This peel-off gel mask consists of ascorbic acid, polyvinyl alcohol (PVA, as preservative), polyethylene glycol (PEG), glycerine (as plasticizer), polysorbate (tween 20, as stabilizer), ethanol and distilled water with the addition of St. John's Wort Oil and active carbon. The peel-off physical properties (homogeneity, spreadability, viscosity, film-drying time), chemical properties (pH value, stability and antibacterial activity properties) were examined. Using of an active ingredient in peel off mask, it strengthens the role of peel off mask by opening the clogged pores. Activated carbon (AC) was added to this formulation as an active ingredient due to its adsorbent activity. In this present study, activated carbon was obtained from pine cone (PC). The specific surface area (SBET) of activated carbon was found to be 536.998 m²/g. The antimicrobial activity of the St. John's Wort oil was tested against Gram-negative bacteria (Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus) as well as one pathogenic fungus (Candida albicans, ATCC 10231). Disc diffusion method was used to study antimicrobial activity. The prepared peel of mask showed a good peeling feature without causing edema or irritation on the skin and that it can increase skin cleansing by removing the dirt in the skin pores.

Kaynakça

  • Ridwanto R, Lubis M, Syahputra R, Inriyani H. Utilisation of biopolymer combination as a material for making gel peel off mask. Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education. AISTSSE 18-19 October 2018, Medan, Indonesia.
  • Somwanshi S, Kudale K, Dolas R, Kotade K. Formulatıon and evaluatıon of cosmetıc herbal face pack for glowıng skın. International Journal of Pharmacy and Biological Sciences. 2018:8 (4):49-52. https://doi.org/ 10.7897/2277-4343.083199.
  • Rum I, Suherman H. Formulation and evaluation of peel-off gel mask from whole milk yogurt and seaweed (Eucheuma cottonii) as antioxidants sources. Pharmacy & Pharmacology International Journal. 2021;9(4):132‒135. https://doi.org/10.15406/ppij.2021.09.00338.
  • Kulkarnı S, Gupta D, Bhawsar S. Formulatıon and evaluatıon of actıvated charcoal peel off mask. International Journal of Pharmacy Research & Technology. 2019; 9 (2): 44-48. https://doi.org/10.31838/ijprt/09.02.06.
  • Beringhs A, Rosa J, Stulzer H, Budal R. Sonaglio D. Green clay and aloe vera peel-off facial masks: response surface methodology applied to the formulation design. AAPS Pharm Sci Tech. 2013;14(1):444-455. https://doi.org/10.1208/s12249-013-9930-8.
  • Budiman A, Aulifa D, Kusuma A, Kurniawan I, Sulastri A. Peel-off gel formulation from black mulberries (Morus nigra) extract as anti-acne mask. January National Journal of Physiology Pharmacy and Pharmacology. 2017; 7(10):987-994. https://doi.org/10.5455/njppp.2017.7.0413123052017.
  • Vieira R, Fernandes A, Kaneko T, Consiglieri V, Pinto C, Pereira C, et al. Physical and physicochemical stability evaluation of cosmetic formulations containing soybean extract fermented by Bifidobacterium animalis. Brazilian Journal of Pharmaceutical Science. 2009; 45(3):515-525.https://doi.org/10.1590/S1984-82502009000300018.
  • Iqbal M, Ashiq M. Adsorption of dyes from aqueous solutions on activated charcoal. Journal of Hazardous Materials B. 2007; 139: 57–66. https://doi.org/10.1016/j.jhazmat.2006.06.007.
  • Demirak A, Keskin F, Şahin Y, Kalemci V. Removal of ammonium from water by pine cone powder as biosorbent. Mugla Journal of Science and Technology. 2015; 1(1): 5-12. https://doi.org/10.22531/muglajsci.209992.
  • Gaudreault P. Activated Charcoal Revisited. Clinical Pediatric Emergency Medicine. 2005; 6(2) :76-80. https://doi.org/10.1016/j.cpem.2005.04.005.
  • Bhomick P, Supong A, Baruah M, Pongener C, Sinha D. Pine Cone biomass as an efficient precursor for the synthesis of activated biocarbon for adsorption of anionic dye from aqueous solution: Isotherm, kinetic, thermodynamic and regeneration studies. Sustainable Chemistry and Pharmacy. 2018; 10:41–49. https://doi.org/10.1016/j.scp.2018.09.001.
  • Bhat M, Yadav N, Hashmi S. Pinecone-derived porous activated carbon for high performance all-solid-state electrical double layer capacitors fabricated with flexible gel polymer electrolytes. Electrochimica Acta. 2019; 304:94-108. https://doi.org/10.1016/j.electacta.2019.02.092.
  • Eroglu E. Girgin S. A unique phenolic extraction method from olive oil macerate of Hypericum perforatum using DMSO: Assessment of in vitro anticancer activity, LC-MS/MS profile, total phenolic content and antioxidant capacity. South African Journal of Botany. 2021; 139: 6-11. https://doi.org/10.1016/j.sajb.2021.01.015.
  • Orhan I, Kartal M, Gülpinar A, Cos P, Matheeussen A, Maes L. et al. Assessment of antimicrobial and antiprotozoal activity of the olive oil macerate samples of Hypericum perforatum and their LC-DAD-MS analyses. Food Chemistry. 2013;138 (2–3):870-875. https://doi.org/10.1016/j.foodchem.2012.11.053.
  • Maisenbacher P, Kovar K. Analysis and stability of Hyperici oleum, Planta Med. 1992; 58(4): 351-354. https://doi.org/10.1055/s-2006-961483.
  • Isacchi B, Bergonzi M, Carnevali F, Esch S, Vincieri F, Bilia A. Analysis and stability of the constituents of St. John’s wort oils prepared with different methods. Journal of Pharmaceutical and Biomedical Analysis. 2007; 45: 756–761. https://doi.org/10.1016/j.jpba.2007.08.025.
  • Gîtea D, Şıpoş M, Mırcea T, Paşca B. The analysis of alcoholic extracts of hypericum species by: UVv/Vis spectrophotometry. Analele Universităţii din Oradea-Fascicula Biologie Tom. XVII / 1, 2010: 111-115.
  • Milosevic T, Solujıc S, Sukdolak S. In vitro study of ethanolic extract of Hypericum perforatum L. on growth and sporulation of some bacteria and fungi. Turkish Journal of Biology. 2007: 31: 237-241.
  • Eğri Ö, Erdemir N. Production of Hypericum perforatum oil-loaded membranes for wound dressing material and in vitro tests. Artıfıcıal Cells, Nanomedıcıne, And Bıotechnology. 2019; 47(1) :1404–1415. https://doi.org/10.1080/21691401.2019.1596933.
  • Zhang J, Feng C, Ge P, Wang Q, Liu Y, Xu H, Zhou X. High purity separation of hypericin from Hypericum perforatum L. Extract with macroporous resin column coupling preparative liquid chromatography. Process Biochemistry. 2021; 103: 107–113. https://doi.org/10.1016/j.procbio.2021.02.012.
  • Jarzębski M, Smułek W, Baranowska H, Masewicz L, Kobus-Cisowska J, Ligaj M, et al. Characterization of St. John’s wort (Hypericum perforatum L.) and the impact of filtration process on bioactive extracts incorporated into carbohydrate-based hydrogels. Food Hydrocolloids. 2020; 104: 105748. https://doi.org/10.1016/j.foodhyd.2020.105748.
  • Shimamori Y. Mitsunaka S, Yamashita H, Suzuki T, Kitao T, Kubori T, et al. Staphylococcal Phage in Combination with Staphylococcus epidermidis as a Potential Treatment for Staphylococcus aureus-Associated Atopic Dermatitis and Suppressor of Phage-Resistant Mutants. Viruses. 2021; 13 (7). https://dx.doi.org/10.3390/v13010007.
  • Magnifico I, Petronio G, Venditti N, Cutuli M, Pietrangelo L, Vergalito F, et al. Atopic dermatitis as a multifactorial skin disorder. Can the analysis of pathophysiological targets represent the winning therapeutic strategy. Pharmaceuticals. 2020; 13(411). https://doi.org/10.3390/ph13110411.
  • Lubbe J. Secondary infections in patients with atopic dermatitis. American Journal of Clinical Dermatology. 2003; 4 (9):641-654. https://doi.org/10.2165/00128071-200304090-00006.
  • Nowicka D, Chilicka K, Dziendziora-Urbinska I. Host-microbe interaction on the skin and its role in the pathogenesis and treatment of atopic dermatitis. Pathogens. 2022; 11 (71). https://doi.org/10.3390/pathogens11010071.
  • Lacour J. Skin microbiota and atopic dermatitis: toward new therapeutic options?. Annales de Dermatologie et de Vénéréologie. 2015;142(1):18-22. https://doi.org/10.1016/S0151-9638(15)30003-X.
  • Li K, Tian S, Jiang J, Wang J, Chen X, Yan F. Pine cone shells-based activated carbon used for CO2 adsorption. Journal of Materials Chemistry A. 2016;4(14):5223–5234. https://doi.org/10.1039/C5TA09908K.
  • Arsić I. Preparation and characterization of St. John’s Wort herb extracts using olive, sunflower and palm oils. Acta Facultatis Medicae Naissensis. 2016;33(2):119-126. https://doi.org/10.1515/afmnai-2016-0013.
  • Aydın G, Şirin N, Kekeçoğlu M, Türken T, Sipahi N., Göksu H. The use of natural preservative propolis and hypericum perforatum oil in herbal cream production. International Journal of Traditional and Complementary Medicine Research. 2021; 2 (1): 27 – 35. https://dergipark.org.tr/tr/pub/ijtcmr/issue/61352/807509.
  • Tanjung Y, Julıantı A, Isnayantı I, Ricsa A. Formulation and evaluatıon of peel off gel facıal mask from arabica coffee fruıt peel extract (coffea arabica L.). International Journal of Applied Pharmaceutics. 2021;13(4):148-151. https://doi.org/10.22159/ijap.2021.v13s4.43845
  • Bhalodia R, Shukla J. Antibacterial and antifungal activities from leaf extracts of cassia fistula l.: An ethnomedicinal plant. J. Adv. Pharm. Technol. Res. 2011; 2:104-109. https://doi.org/ 10.4103/2231-4040.82956.
  • Daoud A, Malika D, Bakari S, Hfaiedh N, Mnafgui K, Kadri A, et al. Assessment of polyphenol composition, antioxidant and antimicrobial properties of various extracts of date palm pollen (DPP) from two Tunisian cultivars. Arab. J. Chem. 2015;12(8) 3075-3086. https://doi.org/10.1016/j.arabjc.2015.07.014.
  • Ahmad I, Sheraz M, Ahmed S, Shaikh R, Vaid F, Khattak S, et al. Photostability and interaction of ascorbic acid in cream formulations. AAPS PharmSciTech. 2011;12(3):917. https://doi.org/ 10.1208/s12249-011-9659-1.
  • Sheraz M, Khan M, Ahmed S, Kazi S, Khattak S, Ahmad, I. Factors affecting formulation characteristics and stability of ascorbic acid in water-in-oil creams. International Journal of Cosmetic Science. 2014;36: 494–504. https://doi.org/10.1111/ics.12152.
  • Sarabandi D, Roudini G, Barahuie F. Activated carbon derived from pine cone as a framework for the preparation of n-heptadecane nanocomposite for thermal energy storage. Journal of Energy Storage. 2019; 24100795. https://doi.org/10.1016/j.est.2019.100795.
  • Assefi M, Davar F, Hadadzadeh H. Green synthesis of nanosilica by thermal decomposition of pine cones and pine needles. Advanced Powder Technology. 2015; 26: 1583–1589. https://doi.org/10.1016/j.apt.2015.09.004.
  • Zsirka B, Horvath E, Jarvas Z, Dallos A, Mako E, Kristof J. Structural and energetical characterization of exfoliated kaolinite surfaces. Appl. Clay Sci. 2016;124-125: 54-61. https://doi.org/10.1016/j.clay.2016.01.035.
  • Sajjad M, Sarwar R, Ali T, Khan L, Mahmood S. Cosmetic uses of activated charcoal. International Journal of Community Medicine and Public Health. 2021; 8: 4572-4574. https://dx.doi.org/10.18203/2394-6040.ijcmph20213569.
  • Orchard A, Vuuren S. Commercial essential oils as potential antimicrobials to treat skin diseases. Evidence-Based Complementary and Alternative Medicine. 2017;4517971: 92. https://doi.org/10.1155/2017/4517971.
  • Elgayyar M, Draughon F. A, Golden D. A, Mount J. R. Antimicrobial activity of essential oils from plants against selected pathogenic and saprophytic microorganisms. Journal of Food Protection. 2001; 64:1019–1024. https://doı: 10.4315/0362-028x-64.7.1019.
  • Burt S. Essential oils: their antibacterial properties and potential applications in foods-a review. Int. J. Food Microbiol. 2004;94: 223–253. https://doı:10.1016/j.ijfoodmicro.2004.03.022.
  • Badnore A, Sorde K, Datir K, Ananthanarayan L, Pratap A, Pandit A. Preparation of antibacterial peel-off facial mask formulation incorporating biosynthesized silver nanoparticles. Applied Nanoscience. 2019;9: 279–287. https://doi.org/10.1007/s13204-018-0934-2.
  • Rahmasari D, Ermawati D, Weka Nugraheni R, Ramadhaningtyas Putri D, Nur Pratiwi I. Design and development of peel-off mask gel formulation of citronella oil for acne vulgaris. In Proceedings of the 2nd Health Science International Conference (HSIC 2019), 157-163. ISBN: 978-989-758-462-6. https://doi.org/10.5220/0009126101570163.
  • Ali S, Yosipovitch G. Skin pH: From Basic Science to Basic Skin Care. Acta Derm Venereol. 2013; 93: 261–267. https://doi.org/10.2340/00015555-1531.
  • Hariyadi D, Isnaeni I, Sudarma S, Suciati S, Rosita N. Peel-off emulgel mask of Cocos nucifera L. extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827. Journal of Advanced Pharmaceutical Technology & Research, 2022;11 (4): 220-225. https://doi.org/10.4103/japtr.JAPTR_51_20from: https://www.fhi.no/nettpub/utbruddsveilederen/
Toplam 45 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Fiziksel Kimya (Diğer)
Bölüm Makaleler
Yazarlar

Hatice Karaer Yağmur 0000-0002-3728-1825

Hatice Kübra Özer Bu kişi benim 0009-0003-5666-5538

Yayımlanma Tarihi 26 Eylül 2025
Gönderilme Tarihi 21 Ocak 2025
Kabul Tarihi 2 Eylül 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 14 Sayı: 3

Kaynak Göster

APA Karaer Yağmur, H., & Özer, H. K. (2025). Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone. Türk Doğa ve Fen Dergisi, 14(3), 156-164. https://doi.org/10.46810/tdfd.1624013
AMA Karaer Yağmur H, Özer HK. Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone. TDFD. Eylül 2025;14(3):156-164. doi:10.46810/tdfd.1624013
Chicago Karaer Yağmur, Hatice, ve Hatice Kübra Özer. “Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone”. Türk Doğa ve Fen Dergisi 14, sy. 3 (Eylül 2025): 156-64. https://doi.org/10.46810/tdfd.1624013.
EndNote Karaer Yağmur H, Özer HK (01 Eylül 2025) Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone. Türk Doğa ve Fen Dergisi 14 3 156–164.
IEEE H. Karaer Yağmur ve H. K. Özer, “Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone”, TDFD, c. 14, sy. 3, ss. 156–164, 2025, doi: 10.46810/tdfd.1624013.
ISNAD Karaer Yağmur, Hatice - Özer, Hatice Kübra. “Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone”. Türk Doğa ve Fen Dergisi 14/3 (Eylül2025), 156-164. https://doi.org/10.46810/tdfd.1624013.
JAMA Karaer Yağmur H, Özer HK. Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone. TDFD. 2025;14:156–164.
MLA Karaer Yağmur, Hatice ve Hatice Kübra Özer. “Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone”. Türk Doğa ve Fen Dergisi, c. 14, sy. 3, 2025, ss. 156-64, doi:10.46810/tdfd.1624013.
Vancouver Karaer Yağmur H, Özer HK. Formulation and evaluation of peel-off gel mask with St. John’s Wort oil and activated carbon from pine cone. TDFD. 2025;14(3):156-64.