Change as the destiny of humanity, is a vital reality in interaction with religion in social life. In this sense, social change refers to rooted and permanent changes in society's structure and the established social system. On the other hand, religion can be considered as a belief system and a lifestyle connected to it for people. Religion, which brings the principles of belief and practice in understanding, significating and living life for humans, aims to regulate and organize social life. Based on this purpose, religion aims at establishing, structuring or organizing the society and guiding people in belief, thought, mindset and practice. While interacting with the existing social order and culture, stability, emerging new situations and the reality of change, it redefines and reconstructs them or becomes a factor in their realization with its principles and beliefs. In this context, the relationship between religion and social change is an essential issue in understanding and significating religion and religious and social life. As a matter of fact, this study deals with the relationship between religion and social change in the case of Islam and Muslims. The study aims to understand, explain and make sense of the dimension of social change in the Islamic religion and Muslims. Within the framework of this purpose, it aims to contribute to social sciences in terms of studies on the subject.