Analyis of Morphological Characteristics of Polyamide 6/Chitosan Blended Nanofibers Fabricated by Electrospinning

Yıl 2013, Cilt: 12 Sayı: 24, 53 - 65, 01.12.2013

Ramazan Erdem Erhan Sancak

Öz

In our study, various ratios of Polyamide 6 and Chitosan blended nanofibers in the nanofibrous composite form obtained via electrospinning at ambient atmosphere. Homogenous Chitosan solutions were prepared in aqeous acetic acid. Polyamide 6 was dissolved in formic acid. Properties of all blended solutions were determined by measuring viscosity, conductivity and pH values. It was recorded that when the Chitosan content increased in the blend solution, viscosity was also increased, however, conductivity was decreased. SEM analysis was conducted to investigate the characteristics of the final nanofibrous composite structures. Beadless and uniform nanofibers were obtained and the diameter of the fibers ranged from 87±22nm to 44±26nm

Anahtar Kelimeler

Electrospinning, polyamide 6, chitosan, nanofiber

Elektroçekim Yöntemiyle Elde Edilen Poliamid 6/Kitosan Bazlı Nanoliflerin Morfolojik Özelliklerinin İncelenmesi

Öz

Çalışmamızda, elektroçekim yöntemiyle çeşitli karışım oranlarında Poliamid 6 ve Kitosan içeren nanolif bazlı kompozit yapılar elde edilmiştir. Kitosan, asetik asit ile Poliamid 6 ise formik asit yardımıyla çözülmüştür. Çözeltilere ait özellikler, viskozite, iletkenlik ve pH ölçümleri ile saptanmıştır. Karışımdaki Kitosan miktarı arttıkça, iletkenliğin azaldığı, viskozitenin ise arttığı kaydedilmiştir. Nanolif bazlı kompozit yapıların morfolojik özellikleri SEM analizleri ile tespit edilmiştir. Elektroçekim işlemi sonucu düzgün ve hatasız lifler elde edilmiştir. Lif incelikleri 87±22nm ve 44±26nm aralığında değişim göstermiştir

Anahtar Kelimeler

Elektroçekim, poliamid 6, kitosan, nanolif

Kaynakça

• Chong, E.J., Phan, T.T., Lim, I.J., Zhang, Y.Z., Bay, B.H., Ramakrishna, S., Lim, C.T. (2007), Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution. Acta Materialia, 3: 321–330.
• Desai, K., Kit, K. (2008), Effect of spinning temperature and blend ratios on electrospun chitosan/poly(acrylamide) blends fibers. Polymer, 49: 4046–4050.
• Geng, X., Kwon, O.H., Jang, J. (2005), Electrospinning of chitosan dissolved in concentrated acetic acid solution. Biomaterials., 26: 5427–32.
• Li, L., Hsieh, Y-L. (2006), Chitosan bicomponent nanofibers and nanoporous fibers. Carbohydrate Research, 341: 374–81.
• Li, D., Wang, Y., Xia, Y. (2004), Electrospinning nanofibers as uniaxially aligned arrays and layerby- layer stacked films. Advanced Materials,16: 361–366.
• Li, D., Xia, Y.N. (2004), Electrospinning of nanofibers: Reinventing the wheel?. Advanced Materials, 16: 1151–1170.
• Min, B.M., Lee, S.W., Lim, J.N., You, Y., Lee, T.S., Kang, P.H., Park, W.H. (2004), Chitin and chitosan nanofibers: Electrospinning of chitin and deacetylation of chitin nanofibers. Polymer, 45: 7137–7142.
• Nirmala, R., Nam, K.T., Soo-Jin Park, Yu-Shik Shin, R. Navamathavan, Hak Yong Kim, H.Y. (2010), Formation of high aspect ratio polyamide-6 nanofibers via electrically induced double layer during electrospinning. Applied Surface Science, 256: 6318–6323.
• Nirmala, R., Navamathavan, R., Kang, H-S., El-Newehy, M.H., Kim, H.K. (2011), Preparation of polyamide-6/chitosan composite nanofibers by a single solvent system via electrospinning for biomedical applications, Colloids and Surfaces B: Biointerfaces, 83: 173-178.
• Peter, M.G. (1996), Applications and environmental aspects of chitin and chitosan. Journal of Macromolecular Science: Pure and Applied Chemistry, 32: 629–640.
• Queen, H. (2006), Electrospinning Chitosan-Based Nanofibers For Biomedical Applications North Carolina State University, Master Thesis, NC State University. http://www.lib.ncsu.edu/resolver/1840.16/13
• Rao, S.B., Sharma, C.P. (1994), Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. Journal of Biomedical Materials Research, 34: 21– 28.
• Rinaudo, M. (2006), Chitin and chitosan: Properties and applications. Progress in Polymer Science, 31: 603–632.
• Schaefgen, J.R., Trivisonno, C.F. (1951), Polyelectrolyte behavior of polyamides. I. Viscosities of solutions of linear polyamides in formic acid and sulfuric acid. Journal of the American Chemical Society, 73: 4580–4585.
• Subramanian, A., Vu, D., Larsen, G.F., Lin, H-Y. (2005), Preparation and evaluation of the electrospun chitosan/PEO fibers for potential applications in cartilage tissue engineering. Journal of Biomaterials Science, Polymer Edition, 16-7: 861–873.
• Supaphol, P., Mit-Uppatham, C., Nithitanaku, M. (2005), Ultrafine Electrospun Polyamide-6 Fibers: Effects of Solvent System and Emitting Electrode Polarity on Morphology and Average Fiber Diameter. Macromolecular Materials and Engineering, 290: 933–942.
• Tikhonov, V.E., Stepnova, E.A., Babak, V.G., Yamskov, I.A., Palma-Guerrero, J., Jansson, H.B., Lopez-Llorca, L.V., Salinas, J., Gerasimenko, D.V., Avdienko, I.D., Varlamov V.P. (2006), Bactericidal and antifungal activities of a low molecular weight chitosan and its N-/2(3)-(dodec-2-enyl)succinoyl/-derivatives. Carbohydrate Polymers, 64: 66–72.
• Yang, W., Fu, J., Wang, D., Wang, T., Wang, H., Jin, S., He, N. (2010), Study on Chitosan/Polycaprolactone Blending Vascular Scaffolds by Electrospinning. Journal of Biomedical Nanotechnology, 6-3: 254-259.
• Zhang, H., Li, S., White, C.J.B., Ning, X., Nie, H., Zhu, L. (2009), Studies on electrospun nylon-6/chitosan complex nanofiber interactions. Electrochimica Acta, 54: 5739–5745.
• Zhang, Y., Huang, X., Duan, B., Wu, L., Li, S., Yuan, X. (2007), Preparation of electrospun chitosan/poly(vinyl alcohol) membranes. Colloid and Polymer Science, 285:855–863.