Are the optic nerve head parameters and retinal nerve fiber layer thickness affected in patients who had a mild Covid- 19 infection?

Öz

Aim: The aim of this study was to evaluate the peripapillary retinal nerve fiber layer (RNFL) thickness and optic nerve head (ONH) parameters by using a spectral domain optical coherence tomography (SD-OCT) device in patients who had a history of a mild-COVID-19 infection. Material and Methods: This prospective cross-sectional study included 70 patients who had a history of a mild COVID-19 infection and 65 healthy individuals. After detailed ophthalmological examination, the peripapillary RNFL thickness and ONH parameters were measured with the SD-OCT device in all patients. Results: No significant difference was present between the groups in terms of age and gender (p=0.907, p=0.979, respectively). The mean, superior, inferior, nasal, and temporal peripapillary RNFL thicknesses were not statistically significantly different between the groups (p=0.797, p=0.488, p=0.079, p=0.820, p=0.820, respectively). Regarding the ONH parameters, no significant difference was found between the groups in terms of disc area, cup area, rim area, cup/disc ratio, horizontal and vertical cup/disc ratio and cup and rim volume (p=0.239, p=0.995, p=0.522, p=0.959, p=0.716, p= 0.873, p=0.476, p=0.701, respectively). Conclusion: No significant difference was found between the patients who had a mild COVID-19 infection and the control group in terms of the peripapillary RNFL thickness and ONH parameters. However, the results may vary according to the severity of the infection and the acute and long-term data.

Anahtar Kelimeler

• COVID-19
• peripapillary retinal nerve fiber layer thickness
• optic nerve head parameters
• optic coherence tomography

Destekleyen Kurum

Yazının herhangi bir finansal desteği yoktur.

Hafif Covid-19 enfeksiyonu geçiren hastalarda optik sinir başı parametreleri ve retina sinir lifi tabakası kalınlığı etkilenir mi?

Öz

Amaç: Bu çalışmanın amacı hafif COVID-19 enfeksiyonu geçiren hastalarda peripapiller retina sinir lifi tabakası (RSLT) kalınlığı ve optik sinir başı (OSB) parametrelerini, spektral domain optik koherens tomografi (SD-OKT) cihazı kullanarak değerlendirmektir. Gereç ve Yöntemler: Bu prospektif cross-sectional çalışmaya hafif COVID -19 enfeksiyonu geçirmiş 70 hasta ile 65 sağlıklı birey dahil edildi. Ayrıntılı oftalmolojik muayene sonrası tüm hastalara SD-OKT cihazı ile peripapiller RSLT kalınlığı ve OSB parametrelerinin ölçümleri yapıldı. Bulgular: Gruplar arasında yaş ve cinsiyet açısından anlamlı farklılık yoktu (p=0.907, p=0.979, sırasıyla). Ortalama, superior, inferior, nazal ve temporal peripapiller RSLT kalınlığı, gruplar arasında istatistiksel açıdan anlamlı değildi (p=0.797, p=0.488, p=0.079, p=0.820, p=0.820, sırasıyla). OSB parametrelerine bakıldığında disc alanı, cup alanı, rim alanı, cup/disc oranı, horizontal ve vertical cup/disc oranı, cup ve rim volume açısından gruplar arasında anlamlı farklılık tespit edilmedi (p=0.239, p= 0.995, p=0.522, p=0.959, p=0.716, p= 0.873, p=0.476, p=0.701, sırasıyla). Sonuçlar: Hafif COVID-19 enfeksiyonu geçiren hastalarla kontrol grubu arasında peripapiller RSLT kalınlığı ve OSB parametreleri açısından anlamlı farklılık tespit edilmedi. Ancak bulduğumuz bu sonuçlar enfeksiyonun şiddeti ile enfeksiyonun akut ve uzun dönem verilerine göre değişkenlik gösterebilir.

Anahtar Kelimeler

• COVID-19
• peripapiller retina sinir lifi tabakası kalınlığı
• optik sinir başı parametreleri
• optik koherens tomografi

Kaynakça

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