Effect of music ıntervention on anxiety levels in cancer patients receiving radiotherapy

Öz

Aim: Diagnosis and treatment of malignancies may cause distress in patients. Complementary treatments like music intervention to relieve anxiety of cancer patients is a new paradigm. We aimed to evaluate the effect of music intervention on anxiety in patients undergoing radiotherapy. Material and Methods: One hundred patients who received radiotherapy with curative intent were included in the study. Patients were divided into music intervention and control groups. Each group consisted of 50 patients but three patients from the music intervention group and 2 patients from the control group were excluded from the analysis because they could not completely fill in the questionnaires. In music intervention group patients selected the type of music they desired to listen freely during radiotherapy. Music intervention was not used in the control group during radiotherapy.. Anxiety levels were evaluated with STAI-I and BAI questionnaires after the first session of radiotherapy in both groups. STAI-II was implemented before radiotherapy Results: Forty-eight patients in the control and 47 patients in the music intervention group were included in the analyses. The mean STAI-I scores after radiotherapy were 42.1 ± 11.1 and 29.9 ± 6.7 in the control and music intervention groups, respectively with a statistically significant intergroup difference (p=0.000). The mean BAI scores after RT were 19.96 ± 6.3 and 13.3 ± 3.1 in the control and music intervention groups, respectively with a statistically significant difference. (p=0.000). Conclusion: Music intervention during radiotherapy sessions may be effective on reducing the radiotherapy-related anxiety in cancer patients.

Anahtar Kelimeler

• Cancer
• Anxiety
• Music interventions
• Radiotherapy

Kanser hastalarında radyoterapi sırasında müzik dinlemenin anksiyete seviyelerine etkisi

Öz

Amaç: Kanser tanı ve tedavisi hastalarda kaygıya neden olabilmektedir. Kanserli hastaların kaygılarını azaltmak için müzik müdahalesi gibi tamamlayıcı tedaviler güncel yaklaşımlardır. Bu çalışmada Radyoterapi alan hastalarda müzik müdahalesinin kaygı üzerine etkisini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Küratif amaçlı radyoterapi alan 100 hasta çalışmaya dahil edildi. Hastalar müzik müdahale ve kontrol gruplarına ayrıldı. Her grup 50 hastadan oluşmakta ancak müzik müdahale grubundan 3, kontrol grubundan 2 hasta anketleri tamamlayamadıklarından analize dahil edilmediler. Müzik müdahale grubundaki hastalar radyoterapi sırasında dinleyecekleri müzik türünü kendileri seçtiler. Kontrol grubuna radyoterapi sırasında müzik dinletilmedi. Her iki grupta ilk radyoterapi uygulaması sonrası kaygı düzeyleri STAI-I ve BAI anketleri ile değerlendirildi. Bulgular: Kontrol grubunda 48 hasta ve müzik grubunda 47 hasta analiz edildi. Radyoterapi sonrası ortalama STAI-I skorları kontrol ve müzik gruplarında sırasıyla 42.1 ± 11.1 ve 29.9 ± 6.7 olarak bulundu ve istatistiksel olarak farklılık vardı (p=0.000). Radyoterapi sonrası ortalama BAI skorları kontrol ve müzik gruplarında sırasıyla 19.96 ± 6.3 and 13.3 ± 3.1 olarak bulundu ve istatistiksel olarak farklılık vardı (p=0.000). Sonuç: Radyoterapi sırasında müzik dinlemek kanser hastalarında kaygıyı azaltmada etkili olabilmektedir.

Anahtar Kelimeler

• kanser
• kaygı
• müzik müdahaleleri
• radyoterapi

Kaynakça

1. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249.
2. Baskar R, Lee KA, Yeo R, et al. Cancer and radiation therapy: current advances and future directions. Int J Med Sci. 2012;9(3):193-9.
3. Sharma N, Purkayastha A. Prevalence of anxiety and depression in cancer patients during radiotherapy: A rural Indian perspective. J Cancer Res Ther. 2021 Jan-Mar;17(1):218-224.
4. Nardone V, Vinciguerra C, Correale P, et al. Music therapy and radiation oncology: State of art and future directions. Complement Ther Clin Pract. 2020 May;39:101124.
5. Habboush Y, Shannon RP, Niazi SK, et al. Patient-reported distress and survival among patients receiving definitive radiation therapy. Adv Radiat Oncol. 2017 Apr-Jun;2(2):211-219.
6. Warth M, Kessler J, Hillecke TK, et al. Music Therapy in Palliative Care. Dtsch Arztebl Int. 2015 Nov 13;112(46):788-94.
7. Stanczyk MM. Music therapy in supportive cancer care. Rep Pract Oncol Radiother. 2011 Jun 8;16(5):170-2.
8. Bradt J, Dileo C, Magill L, et al. Music interventions for improving psychological and physical outcomes in cancer patients. Cochrane Database of Systematic Reviews. 2016 (8).

9. Gramaglia C, Gambaro E, Vecchi C, et al. Outcomes of music therapy interventions in cancer patients-A review of the literature. Crit Rev Oncol Hematol. 2019 Jun;138:241-254.
10. Kondo H, Morishita M, Osaka N, et al. Functional roles of the cingulo-frontal network in performance on working memory. Neuroimage. 2004 Jan;21(1):2-14.
11. Valet M, Sprenger T, Boecker H, et al. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain--an fMRI analysis. Pain. 2004 Jun;109(3):399-408.
12. Yeo JK, Cho DY, Oh MM, et al. Listening to music during cystoscopy decreases anxiety, pain, and dissatisfaction in patients: a pilot randomized controlled trial. J Endourol. 2013 Apr;27(4):459-62.
13. Chang YH, Oh TH, Lee JW, et al. Listening to music during transrectal ultrasound-guided prostate biopsy decreases anxiety, pain and dissatisfaction in patients: a pilot randomized controlled trial. Urol Int. 2015;94(3):337-41.
14. Tam WW, Lo KK, Hui DS. The effect of music during bronchoscopy: A meta-analysis. Heart Lung. 2016 Mar-Apr;45(2):86-94.
15. Costa A, Montalbano LM, Orlando A, et al. Music for colonoscopy: A single-blind randomized controlled trial. Dig Liver Dis. 2010 Dec;42(12):871-6.
16. Zhang ZS, Wang XL, Xu CL, et al. Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy. J Endourol. 2014 Jun;28(6):739-44.
17. Öner N, Le Compte A. State-Trait Anxiety Inventory Handbook. Boğaziçi University Press, Istanbul; 1983.
18. Julian LJ. Measures of anxiety: State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11(0 11):S467-72.
19. Elith CA, Perkins LS, Johnson MH, et al. Can relaxation interventions reduce anxiety in patients receiving radiotherapy? outcomes and study validity. The Radiographer 2001;48:27-31.
20. Rossetti A, Chadha M, Torres BN, et al. The Impact of Music Therapy on Anxiety in Cancer Patients Undergoing Simulation for Radiation Therapy. Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):103-110.
21. Chen LC, Wang TF, Shih YN, et al. Fifteen-minute music intervention reduces pre-radiotherapy anxiety in oncology patients. Eur J Oncol Nurs. 2013 Aug;17(4):436-41.
22. O'Steen L, Lockney NA, Morris CG, et al. A Prospective Randomized Trial of the Influence of Music on Anxiety in Patients Starting Radiation Therapy for Cancer. Int J Radiat Oncol Biol Phys. 2021 Mar 1;109(3):670-674.
23. O'Callaghan C, Sproston M, Wilkinson K, et al. Effect of self-selected music on adults' anxiety and subjective experiences during initial radiotherapy treatment: a randomised controlled trial and qualitative research. J Med Imaging Radiat Oncol. 2012 Aug;56(4):473-7.
24. Hanedan Uslu G. Influence of Music Therapy on the State of Anxiety During Radiotherapy. Turkish Journal of Oncology. 2017.