Araştırma Makalesi
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Acil serviste yaşlı hastaların takipleri sırasında hastane içi kardiyopulmoner arrestlerin ve mortalitenin sebepleri: retrospektifbir çalışma

Yıl 2025, Cilt: 16 Sayı: 2, 343 - 348, 30.06.2025
https://doi.org/10.18663/tjcl.1633778

Öz

Amaç: Bu çalışma, acil servise başvuran yaşlı hastalarda kardiyopulmoner arrest (KPA) gelişimini etkileyen faktörleri, spontan dolaşımın geri dönme (SDGD) olasılığını ve sağkalım oranlarını belirlemeyi amaçlamaktadır.
Gereç ve Yöntemler: 1 Eylül 2022 - 31 Ağustos 2024 tarihleri arasında Esenyurt Necmi Kadıoğlu Devlet Hastanesi acil servisine KPA ile başvuran 65 yaş ve üzeri 500 hastanın verileri retrospektif olarak analiz edildi. Veriler, hastanenin elektronik tıbbi kayıtlarından elde edilerek demografik bilgiler, komorbiditeler, klinik özellikler, resüsitasyon işlemleri ve sağkalım oranları incelendi. İstatistiksel analizler SPSS sürüm 26.0 kullanılarak yapıldı.
Bulgular: Hastaların ortalama yaşı 79,67 ± 8,99 yıl olup, en yaygın komorbiditeler hipertansiyon (%52,6), KOAH (%40,2) ve kardiyovasküler hastalıklar (%35,4) olarak tespit edildi. SDGD sağlayan hastalarda resüsitasyona daha erken başlandığı ve oksijen desteği ile mekanik ventilasyonun SDGD oranlarını anlamlı derecede artırdığı görüldü (p < 0,05). 24 saatlik sağkalım oranı %65 ± 10, 30 günlük sağkalım oranı %45 ± 10 ve hastane içi mortalite oranı %55 ± 10 olarak hesaplandı.
Sonuç: Komorbiditelerin etkili yönetimi ve zamanında yapılan müdahaleler, KPA riskini azaltmada ve yaşlı hastalarda sağkalım oranlarını iyileştirmede kritik öneme sahiptir. Erken ve etkili resüsitasyon stratejileri sağkalım sonuçlarını önemli ölçüde iyileştirmektedir. Klinik yönetim protokollerini optimize etmek için daha geniş hasta gruplarıyla yapılacak ileri çalışmalara ihtiyaç vardır.

Kaynakça

  • Kırılos E. Time critical emergencies: a comprehensive review of rapid decision making in emergency medicine. J Fac Med Oran 2024; 8: 63–1074.
  • Legramante JM, Morciano L, Lucaroni F, Gilardi F, Caredda E, Pesaresi A et al. Frequent Use of Emergency Departments by the Elderly Population When Continuing Care Is Not Well Established. PLoS One. 2016; 11: e0165939.
  • Violan C, Foguet-Boreu Q, Flores-Mateo G, Salisbury C, Blom J, Freitag M et al. Prevalence, determinants and patterns of multimorbidity in primary care: a systematic review of observational studies. PLoS One 2014; 9: e102149.
  • Wang MT, Huang WC, Yen DH, Yeh EH, Wu SY, Liao HH. Potential risk factors for mortality in patients after in hospital cardiac arrest: a retrospective study. Front Cardiovasc Med 2021; 8: 630102.
  • Andersen LW, Holmberg MJ, Berg KM, Donnino MW, Granfeldt A. In-hospital cardiac arrest: a review. JAMA 2019; 321: 1200-10.
  • Zanders R, Druwé P, Van Den Noortgate N, Piers R. The outcome of in and out hospital cardiopulmonary arrest in the older population: a scoping review. Eur Geriatr Med 2021; 12: 45–57.
  • Kleinman ME, Perkins GD, Bhanji F, Billi JE, Bray JE, Callaway CW et al. ILCOR scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care: a consensus statement. Circulation 2018; 137: e802–e819.
  • Hogan H, Hutchings A, Wulff J, Carver C, Holdsworth E, Welch J et al. Interventions to reduce mortality from in hospital cardiac arrest: a mixed methods study. Health Serv Deliv Res 2019; 7: 1–110.
  • Bonnesen K, Szépligeti SK, Szentkúti P, Horváth Puhó E, Sørensen HT, Schmidt M. The impact of comorbidity burden on cardiac arrest mortality: A population-based cohort study. Resuscitation 2024; 202: 110352.
  • Wang MT, Huang WC, Yen DH, Yeh EH, Wu SY, Liao HH. The Potential Risk Factors for Mortality in Patients After In-Hospital Cardiac Arrest: A Multicenter Study. Front Cardiovasc Med 2021; 8: 630102.
  • White L, Melhuish T, Holyoak R, Ryan T, Kempton H, Vlok R. Advanced airway management in out-of-hospital cardiac arrest: A systematic review and meta-analysis. Am J Emerg Med 2018; 36: 2298-306.
  • Panchal AR, Bartos JA, Cabañas JG, Donnino MW, Drennan IR, Hirsch KG et al. Part 3: Adult Basic and Advanced Life Support 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010; 122: S729–S767.
  • Delorenzo A, Nehme Z, Yates J, Bernard S, Smith K. Double sequential external defibrillation for refractory ventricular fibrillation out-of-hospital cardiac arrest: A systematic review and meta-analysis. Resuscitation 2018; 135: 124-9.
  • Chan PS, Nallamothu BK, Krumholz HM, Spertus JA, Li Y, Hammill BG, Curtis LH; American Heart Association Get with the Guidelines–Resuscitation Investigators. Long-term outcomes in elderly survivors of in-hospital cardiac arrest. N Engl J Med 2013; 368: 1019-26.
  • Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Böttiger BW et al. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation. Circulation 2008; 118: 2452–83.
  • Chan PS, Tang Y; American Heart Association's Get With the Guidelines®‐Resuscitation Investigators. Risk-Standardizing Rates of Return of Spontaneous Circulation for In-Hospital Cardiac Arrest to Facilitate Hospital Comparisons. J Am Heart Assoc 2020; 9: e014837.
  • Andersen LW, Bivens MJ, Giberson T, Giberson B, Mottley JL, Gautam S et al. The relationship between age and outcome in out-of-hospital cardiac arrest patients. Resuscitation 2015; 94: 49-54.
  • Okubo M, Komukai S, Andersen LW, Berg RA, Kurz MC, Morrison LJ,. Duration of cardiopulmonary resuscitation and outcomes for adults with in-hospital cardiac arrest: Retrospective cohort study. BMJ 2024; 384: e076019.
  • Yonis H, Andersen MP, Mills EHA, Winkel BG, Wissenberg M, Køber L. Duration of resuscitation and long term outcome after in hospital cardiac arrest: A nationwide observational study. Resuscitation 2022; 179: 267-73.

Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study

Yıl 2025, Cilt: 16 Sayı: 2, 343 - 348, 30.06.2025
https://doi.org/10.18663/tjcl.1633778

Öz

Aim: This study aimed to identify the factors affecting the development of cardiopulmonary arrest (CPA), the probability of return of spontaneous circulation (ROSC), and survival rates in elderly patients admitted to the emergency department.
Material and Methods: A retrospective analysis was conducted on data from 500 patients aged 65 years and older who presented with CPA at Esenyurt Necmi Kadıoğlu State Hospital's emergency department between September 1, 2022, and August 31, 2024. Data were collected from the hospital's electronic medical records, including demographic information, comorbidities, clinical characteristics, resuscitation procedures, and survival rates. Statistical analysis was performed using SPSS version 26.0.
Results: The mean age of the patients was 79.67 ± 8.99 years, with hypertension (52.6%), COPD (40.2%), and cardiovascular diseases (35.4%) being the most common comorbidities. Patients who achieved ROSC had earlier initiation of resuscitation, and oxygen support along with mechanical ventilation significantly improved ROSC rates (p < 0.05). The 24-hour survival rate was 65% ± 10, the 30-day survival rate was 45% ± 10, and the in-hospital mortality rate was calculated as 55% ± 10.
Conclusion: Effective management of comorbidities and timely interventions are essential for reducing CPA risk and improving survival rates in elderly patients. Early and efficient resuscitation strategies significantly improve survival outcomes. Further studies with larger cohorts are recommended to optimize clinical management protocols.

Etik Beyan

This study was approved by the Istanbul Medipol University Non-Interventional Clinical Research Ethics Committee (Approval No: E-10840098-202.3.02-765, Date: 24/01/2025).

Destekleyen Kurum

No funding was received for this study.

Kaynakça

  • Kırılos E. Time critical emergencies: a comprehensive review of rapid decision making in emergency medicine. J Fac Med Oran 2024; 8: 63–1074.
  • Legramante JM, Morciano L, Lucaroni F, Gilardi F, Caredda E, Pesaresi A et al. Frequent Use of Emergency Departments by the Elderly Population When Continuing Care Is Not Well Established. PLoS One. 2016; 11: e0165939.
  • Violan C, Foguet-Boreu Q, Flores-Mateo G, Salisbury C, Blom J, Freitag M et al. Prevalence, determinants and patterns of multimorbidity in primary care: a systematic review of observational studies. PLoS One 2014; 9: e102149.
  • Wang MT, Huang WC, Yen DH, Yeh EH, Wu SY, Liao HH. Potential risk factors for mortality in patients after in hospital cardiac arrest: a retrospective study. Front Cardiovasc Med 2021; 8: 630102.
  • Andersen LW, Holmberg MJ, Berg KM, Donnino MW, Granfeldt A. In-hospital cardiac arrest: a review. JAMA 2019; 321: 1200-10.
  • Zanders R, Druwé P, Van Den Noortgate N, Piers R. The outcome of in and out hospital cardiopulmonary arrest in the older population: a scoping review. Eur Geriatr Med 2021; 12: 45–57.
  • Kleinman ME, Perkins GD, Bhanji F, Billi JE, Bray JE, Callaway CW et al. ILCOR scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care: a consensus statement. Circulation 2018; 137: e802–e819.
  • Hogan H, Hutchings A, Wulff J, Carver C, Holdsworth E, Welch J et al. Interventions to reduce mortality from in hospital cardiac arrest: a mixed methods study. Health Serv Deliv Res 2019; 7: 1–110.
  • Bonnesen K, Szépligeti SK, Szentkúti P, Horváth Puhó E, Sørensen HT, Schmidt M. The impact of comorbidity burden on cardiac arrest mortality: A population-based cohort study. Resuscitation 2024; 202: 110352.
  • Wang MT, Huang WC, Yen DH, Yeh EH, Wu SY, Liao HH. The Potential Risk Factors for Mortality in Patients After In-Hospital Cardiac Arrest: A Multicenter Study. Front Cardiovasc Med 2021; 8: 630102.
  • White L, Melhuish T, Holyoak R, Ryan T, Kempton H, Vlok R. Advanced airway management in out-of-hospital cardiac arrest: A systematic review and meta-analysis. Am J Emerg Med 2018; 36: 2298-306.
  • Panchal AR, Bartos JA, Cabañas JG, Donnino MW, Drennan IR, Hirsch KG et al. Part 3: Adult Basic and Advanced Life Support 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010; 122: S729–S767.
  • Delorenzo A, Nehme Z, Yates J, Bernard S, Smith K. Double sequential external defibrillation for refractory ventricular fibrillation out-of-hospital cardiac arrest: A systematic review and meta-analysis. Resuscitation 2018; 135: 124-9.
  • Chan PS, Nallamothu BK, Krumholz HM, Spertus JA, Li Y, Hammill BG, Curtis LH; American Heart Association Get with the Guidelines–Resuscitation Investigators. Long-term outcomes in elderly survivors of in-hospital cardiac arrest. N Engl J Med 2013; 368: 1019-26.
  • Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Böttiger BW et al. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation. Circulation 2008; 118: 2452–83.
  • Chan PS, Tang Y; American Heart Association's Get With the Guidelines®‐Resuscitation Investigators. Risk-Standardizing Rates of Return of Spontaneous Circulation for In-Hospital Cardiac Arrest to Facilitate Hospital Comparisons. J Am Heart Assoc 2020; 9: e014837.
  • Andersen LW, Bivens MJ, Giberson T, Giberson B, Mottley JL, Gautam S et al. The relationship between age and outcome in out-of-hospital cardiac arrest patients. Resuscitation 2015; 94: 49-54.
  • Okubo M, Komukai S, Andersen LW, Berg RA, Kurz MC, Morrison LJ,. Duration of cardiopulmonary resuscitation and outcomes for adults with in-hospital cardiac arrest: Retrospective cohort study. BMJ 2024; 384: e076019.
  • Yonis H, Andersen MP, Mills EHA, Winkel BG, Wissenberg M, Køber L. Duration of resuscitation and long term outcome after in hospital cardiac arrest: A nationwide observational study. Resuscitation 2022; 179: 267-73.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp
Bölüm Araştırma Makalesi
Yazarlar

Erkan Boğa 0000-0001-6802-6301

Yayımlanma Tarihi 30 Haziran 2025
Gönderilme Tarihi 5 Şubat 2025
Kabul Tarihi 2 Haziran 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 16 Sayı: 2

Kaynak Göster

APA Boğa, E. (2025). Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study. Turkish Journal of Clinics and Laboratory, 16(2), 343-348. https://doi.org/10.18663/tjcl.1633778
AMA Boğa E. Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study. TJCL. Haziran 2025;16(2):343-348. doi:10.18663/tjcl.1633778
Chicago Boğa, Erkan. “Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study”. Turkish Journal of Clinics and Laboratory 16, sy. 2 (Haziran 2025): 343-48. https://doi.org/10.18663/tjcl.1633778.
EndNote Boğa E (01 Haziran 2025) Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study. Turkish Journal of Clinics and Laboratory 16 2 343–348.
IEEE E. Boğa, “Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study”, TJCL, c. 16, sy. 2, ss. 343–348, 2025, doi: 10.18663/tjcl.1633778.
ISNAD Boğa, Erkan. “Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study”. Turkish Journal of Clinics and Laboratory 16/2 (Haziran2025), 343-348. https://doi.org/10.18663/tjcl.1633778.
JAMA Boğa E. Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study. TJCL. 2025;16:343–348.
MLA Boğa, Erkan. “Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study”. Turkish Journal of Clinics and Laboratory, c. 16, sy. 2, 2025, ss. 343-8, doi:10.18663/tjcl.1633778.
Vancouver Boğa E. Causes of in-hospital cardiopulmonary arrests and mortality during the follow-up of elderly patients in the emergency department: a retrospective study. TJCL. 2025;16(2):343-8.


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