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ChatGPT 4 may inappropriately answer questions about managing critically ill patients

Cilt: 16 Sayı: 4 1 Ocak 2026
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ChatGPT 4 may inappropriately answer questions about managing critically ill patients

Öz

Intensive care patients have extremely complex pathologies, making their treatment management difficult. In this study, we aim to evaluate ChatGPT 4, a large language model, regarding its knowledge of critically ill patient management. Scenarios involving mechanical ventilation were created by an intensivist, anesthesiologist, and neurologist working in intensive care units, including head trauma, pulmonary embolism, myocardial infarction, chronic obstructive pulmonary disease, chronic kidney disease, and infective endocarditis, septic shock, and status epilepticus. Questions about patient management related to these scenarios were proposed to ChatGPT 4. Although ChatGPT 4 answered most of the questions correctly, it still requires medical input.

Anahtar Kelimeler

Destekleyen Kurum

This research received no external funding.

Etik Beyan

This study does not require copyrighting for ChatGPT 4 outputs. According to OpenAI's Content Policy and Terms of Use, ChatGPT users own all outputs they create with large language models, including the text and images. We obtained ChatGPT 4’s responses to our designed questions. ChatGPT's answers to our questions are available at: https://github.com/barisaakan/llm-patients

Kaynakça

  1. Lu Y, Wu H, Qi S, Cheng K. Artificial Intelligence in Intensive Care Medicine: Toward a ChatGPT/GPT-4 Way? Ann Biomed Eng. 2023;51:1898-903.
  2. https://github.com/barisaakan/llm-patients
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  4. Chiumello D, Meli A, Pozzi T, Lucenteforte M, Simili P, Sterchele E, Coppola S. Different Inspiratory Flow Waveform during Volume-Controlled Ventilation in ARDS Patients. J Clin Med. 2021;10:4756.
  5. McDonald EG, Aggrey G, Aslan AT, Casias M, Cortes-Penfield N, Dong MQD et al. Guidelines for Diagnosis and Management of Infective Endocarditis in Adults: A WikiGuidelines Group Consensus Statement. JAMA Netw Open. 2023;6:e2326366.
  6. Zhu X, Wang Z, Ferrari MW, Ferrari-Kuehne K, Hsi et al. Management of anticoagulation in patients with infective endocarditis. Thromb Res. 2023;229:15-25.
  7. Ibrahim F, Murr NI. Lafora Disease 2024. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
  8. Parihar R, Ganesh S. Lafora progressive myoclonus epilepsy: Disease mechanism and therapeutic attempts. J Biosci. 2024;49:22.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Yoğun Bakım

Bölüm

Editöre Mektup

Yayımlanma Tarihi

1 Ocak 2026

Gönderilme Tarihi

11 Ağustos 2025

Kabul Tarihi

13 Ekim 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 16 Sayı: 4

Kaynak Göster

APA
Gokcinar, D., Akan, B., Kurşun, O., Gökçınar, A. H., & Akan, B. (2026). ChatGPT 4 may inappropriately answer questions about managing critically ill patients. Turkish Journal of Clinics and Laboratory, 16(4), 688-692. https://doi.org/10.18663/tjcl.1762561
AMA
1.Gokcinar D, Akan B, Kurşun O, Gökçınar AH, Akan B. ChatGPT 4 may inappropriately answer questions about managing critically ill patients. TJCL. 2026;16(4):688-692. doi:10.18663/tjcl.1762561
Chicago
Gokcinar, Derya, Belgin Akan, Oğuzhan Kurşun, Abdullah Halit Gökçınar, ve Barış Akan. 2026. “ChatGPT 4 may inappropriately answer questions about managing critically ill patients”. Turkish Journal of Clinics and Laboratory 16 (4): 688-92. https://doi.org/10.18663/tjcl.1762561.
EndNote
Gokcinar D, Akan B, Kurşun O, Gökçınar AH, Akan B (01 Ocak 2026) ChatGPT 4 may inappropriately answer questions about managing critically ill patients. Turkish Journal of Clinics and Laboratory 16 4 688–692.
IEEE
[1]D. Gokcinar, B. Akan, O. Kurşun, A. H. Gökçınar, ve B. Akan, “ChatGPT 4 may inappropriately answer questions about managing critically ill patients”, TJCL, c. 16, sy 4, ss. 688–692, Oca. 2026, doi: 10.18663/tjcl.1762561.
ISNAD
Gokcinar, Derya - Akan, Belgin - Kurşun, Oğuzhan - Gökçınar, Abdullah Halit - Akan, Barış. “ChatGPT 4 may inappropriately answer questions about managing critically ill patients”. Turkish Journal of Clinics and Laboratory 16/4 (01 Ocak 2026): 688-692. https://doi.org/10.18663/tjcl.1762561.
JAMA
1.Gokcinar D, Akan B, Kurşun O, Gökçınar AH, Akan B. ChatGPT 4 may inappropriately answer questions about managing critically ill patients. TJCL. 2026;16:688–692.
MLA
Gokcinar, Derya, vd. “ChatGPT 4 may inappropriately answer questions about managing critically ill patients”. Turkish Journal of Clinics and Laboratory, c. 16, sy 4, Ocak 2026, ss. 688-92, doi:10.18663/tjcl.1762561.
Vancouver
1.Derya Gokcinar, Belgin Akan, Oğuzhan Kurşun, Abdullah Halit Gökçınar, Barış Akan. ChatGPT 4 may inappropriately answer questions about managing critically ill patients. TJCL. 01 Ocak 2026;16(4):688-92. doi:10.18663/tjcl.1762561

e-ISSN: 2149-8296

Publication Model: Continuous Publication

Peer Review Model: Double-Blind Peer Review

Publication Language: Turkish and English

Access Model: Open Access

DOI Prefix: (Crossref DOI numaranız)

Publisher: DNT Ortadoğu Publishing Inc.

Journal Abbreviation: Turk J Clin Lab

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