Meniere's Disease

Öz

Meniere’s disease also known as idiopathic symptomatic endolymphatic hydrops, is an inner ear disease characterized by spontaneous vertigo attacks, fluctuating hearing loss, ear fullness/pressure sensation and tinnitus. Age of onset is often 50-60 years. History and specific audiometric investigation are used in the diagnosis. Definitive diagnosis is only possible with the histopathological examination, nowadays Meniere's disease is currently placed among the diseases difficult to diagnose with. In the majority of patients, treatment is medical and additional psychological support is recommended. Surgical treatment may be considered in patients who do not respond to medical therapy. In this section, pathogenesis, physiology, symptomatology, diagnosis and treatment of Meniere’s disease will be discussed.

 Key words: Meniere’s disease, vertigo, pathophysiology, diagnosis, treatment.

Meniere Hastalığı

Öz

Meniere hastalığı idiyopatik semptomatik endolenfatik hidrops olarak da bilinen, epizodik spontan vertigo atakları, fluktuasyon gösteren işitme kaybı, kulakta dolgunluk/basınç hissi ve tinnitus ile karakterize bir iç kulak hastalığıdır. Hastalığın başlama yaşları sıklıkla 50-60 yaşlarıdır.Hastalığın teşhisinde anamnez ve spesifik odyometrik testlerden yararlanılır. Kesin tanısının konulması ancak histopatolojik inceleme ile mümkün olduğundan günümüzde halen tanısı zor koyulan hastalıklar arasındadır. Tedavi hastaların büyük kısmında medikaldir ve hastalara psikolojik desteğin eklenmesi önerilir. Medikal tedaviye cevap vermeyen hastalarda cerrahi tedavi gündeme gelebilir. Bu bölümde Meniere hastalığının patogenezi, fizyolojisi, semptomatolojisi, tanı ve tedavi şekilleri ele alınacaktır.

 Anahtar Kelimeler: Meniere hastalığı, vertigo, patofizyoloji, tanı, tedavi.

Anahtar Kelimeler

• Meniere hastalığı, vertigo, patofizyoloji, tanı, tedavi

Kaynakça

1. Paparella MM, Da Costa SS, Fox R, Yoon TH. Meniere’s disease and other labyrinthine disease. Chapter 49. Otolaryngology VolumeII Otology Neuro-Otology 3rd ed. In: Paparella MM, Shumrick DA, eds. 1991. P.1689-714.
2. Schessel D, Minor L, Nedzelski J. Meniere’s disease and other vestibular disorders. Chapter 142. Cummings Otolaryngology Head & Neck Surgery 4th ed.In: Harker LA, ed. 2005. P.3209-53.
3. Saeed SR. Fortnightly review. Diagnosis and treatment of Ménière's disease. BMJ 1998; 316: 368-72.
4. Belinchon A, Perez-Garrigues H, Tenias JM. Evolution of symptoms in Ménière's disease. Audiol Neurootol 2012; 17: 126-32.
5. Nabi S, Parnes LS. Bilateral Ménière's disease. Curr Opin Otolaryngol Head Neck Surg 2009; 17: 356-62.
6. Sarter PM. Vertigo in children. Br Med J 1977; 2: 1416.
7. Pierce NE, Antonelli PJ. Endolymphatic hydrops perspectives 2012. Curr Opin Otolaryngol Head Neck Surg 2012; 20: 416-9.
8. ukuda S, Keithley EM, Harris JP. The development of 15. Akyıldız N. Meniere hastalığı. Kulak hastalıkları ve mikrocerrahisi endolymphatic hydrops following CMV inoculation of the endolymphatic sac. Laryngoscope 1988; 98: 439-43.

9. da Costa SS, de Sousa LC, Piza MR. Meniere's disease: overview, epidemiology, and natural history. Otolaryngol Clin North Am 2002; 35: 455-95.
10. Sennaroglu L, Yilmazer C, Basaran F, Sennaroglu G, Gursel B. Relationship of vestibular aqueduct and inner ear pressure in Ménière's disease and the normal population. Laryngoscope 2001; 111: 1625-30.
11. Veldman J. Immune-mediated sensorineural hearing loss. Auris Nasus Larynx 1998; 25: 309-17.
12. Paparella MM, Djalilian HR. Etiology, pathophysiology of
13. Russell G, Abu-Arafeh I. Paroxysmal vertigo in children an epidemiological study. Int J Pediatr Otorhinolaryngol 1999; 1: 105-7.
14. symptoms, and pathogenesis of Meniere's disease. Otolaryngol
15. Clin North Am 2002; 35: 529-45.
16. Ishiyama G, Ishiyama A, Baloh RW. Drop attacks and vertigo secondary to a non-meniere otologic cause. Arch Neurol 2003; 60: 71-5.
17. Akyıldız N. Endolenfatik hidrops. Kulak Burun Boğaz Hastalıklar ve Baş Boyun Cerrahisi. Editör:Onur Çelik. İstanbul: 2002. S.238-52. II. Ankara: 2002. P.151-86.
18. Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Menière's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol Head Neck Surg 1995; 113: 181-5.
19. Stahle J, Stahle C, Arenberg I.K, Incidence of Me´nie`re’s disease, Arch Otolaryngol 1978; 104: 99-102.
20. Meyerhoff W.L., Paparella M.M., Shea D., Me´nie`re’s disease in children, Laryngoscope 1978; 88: 1504-11.
21. Filipo R, Barbara M. Juvenile Menière’s disease. J Laryngol Otol 1985; 99: 193-6.
22. Bower CM, Cotton RT. The spectrum of vertigo in children. Arch Otolaryngol Head Neck Surg 1995; 121: 911-5.