Evaluation of fructose consumption in individuals with non-alcoholic fatty liver disease

Öz

Aim: The aim of this study was to determine fructose-rich food consumption levels of individuals with nonalcoholic fatty liver disease (NAYKH) and to determine the possible relationship between biochemical parameters and anthropometric measurements.         

 

Material and Methods: Individuals between 19-65 years of age with abdominal ultrasonography (USG) with varying degrees of fatty tissue; mild steatosis (grade 1, n=15), moderate steatosis (grade 2, n=15), severe steatosis (grade 3, n=15) and no steatosis (grade 0, n=15). Nutritional status and 24-hour nutrient consumption were recorded. Anthropometric measurements of individuals, some biochemical findings, physical activity status and fructose-rich nutrition status were investigated. 

 

Results: In this study, anthropometric measurements such as BMI, waist circumference and waist/hip ratio increased with the increase in steatosis degrees and were statistically significant (p<0.001). At physical activity level, there is no significant difference between groups (p=0,099). Daily fructose intake with nutrients is the lowest in grade 0; Grade 2 and Grade 3 groups have similar amounts and higher than other groups (p<0.001). The average daily consumption of fructose-rich non-alcoholic beverages (soda and cola) was found to be at least in grade 0 (8.7 ± 5.7ml) and significantly higher in grade 3 (291 ± 33.5 ml), (p=0,001). Furthermore, in the study individuals with fructose consumption ** BMI, ** waist circumference, * waist / hip ratio, * total cholesterol, ** uric acid, ** ALT, * AST, ** ALP, ** chocolate consumption amount, ** a significant positive relationship was found between the consumption of ready-made fruit juice and alcoholic beverages (* p <0.05, ** p <0.01).

 

Conclusion: In our study, there was a strong correlation between the degree of steatosis and fructose consumption in individuals with NAYKH. It should be kept in mind that excessive consumption of fructose with nutrients may pose a risk for diseases such as obesity, non-alcoholic fatty liver, metabolic syndrome and cardiovascular diseases. The consumption of fructose in daily diet should be provided from natural sources and excessive consumption should be avoided.

Anahtar Kelimeler

• Nonalcoholic fatty liver disease,fructose,high fructose corn syrup,body mass index

Nonalkolik yağlı karaciğer hastalığı olan bireylerde fruktoz tüketiminin değerlendirilmesi

Öz

Aim: The aim of this study was to determine fructose-rich food consumption levels of individuals with nonalcoholic fatty liver disease (NAYKH) and to determine the possible relationship between biochemical parameters and anthropometric measurements.         

 

Material and Methods: Individuals between 19-65 years of age with abdominal ultrasonography (USG) with varying degrees of fatty tissue; mild steatosis (grade 1, n=15), moderate steatosis (grade 2, n=15), severe steatosis (grade 3, n=15) and no steatosis (grade 0, n=15). Nutritional status and 24-hour nutrient consumption were recorded. Anthropometric measurements of individuals, some biochemical findings, physical activity status and fructose-rich nutrition status were investigated. 

 

Results: In this study, anthropometric measurements such as BMI, waist circumference and waist/hip ratio increased with the increase in steatosis degrees and were statistically significant (p<0.001). At physical activity level, there is no significant difference between groups (p=0,099). Daily fructose intake with nutrients is the lowest in grade 0; Grade 2 and Grade 3 groups have similar amounts and higher than other groups (p<0.001). The average daily consumption of fructose-rich non-alcoholic beverages (soda and cola) was found to be at least in grade 0 (8.7 ± 5.7ml) and significantly higher in grade 3 (291 ± 33.5 ml), (p=0,001). Furthermore, in the study individuals with fructose consumption ** BMI, ** waist circumference, * waist / hip ratio, * total cholesterol, ** uric acid, ** ALT, * AST, ** ALP, ** chocolate consumption amount, ** a significant positive relationship was found between the consumption of ready-made fruit juice and alcoholic beverages (* p <0.05, ** p <0.01).

 

Conclusion: In our study, there was a strong correlation between the degree of steatosis and fructose consumption in individuals with NAYKH. It should be kept in mind that excessive consumption of fructose with nutrients may pose a risk for diseases such as obesity, non-alcoholic fatty liver, metabolic syndrome and cardiovascular diseases. The consumption of fructose in daily diet should be provided from natural sources and excessive consumption should be avoided.

Anahtar Kelimeler

• Nonalkolik yağlı karaciğer hastalığı,fruktoz,yüksek fruktozlu mısır şurubu,beden kitle indeksi

Kaynakça

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