Gensini score predicts postoperative atrial fibrillation following on-pump coronary artery bypass grafting

Yıl 2019, Cilt: 10 Sayı: 4, 447 - 451, 31.12.2019

Emir Karaçağlar Arzu Akgün Orçun Çiftci Haldun Müderrisoğlu

https://doi.org/10.18663/tjcl.547919

Öz

Aim:  Postoperative
atrial fibrillation (POAF) is common after coronary artery by-pass grafting
surgery (CABG) and associated with adverse events. GENSINI score is a
widely-used scoring system that quantifies angiographic atherosclerosis. The
value of GENSINI score to predict POAF has not been studied previously. Aim of
this study was to evaluate this relationship in our patients undergoing on-pump CABG surgery.

Material and Methods: In this
retrospective, single-center study, a total of 113 patients without exclusion criteria were included.
Demographic and clinical characteristics of patients were recorded and GENSINI scores
were calculated. Univariate
and multivariate logistic regression analyses were performed to identify the
independent predictors of POAF.

Results: Postoperative atrial fibrillation developed in
34 (30%) patients. Multivariate logistic regression analyses
revealed that C-Reactive Protein [ß=0.037, p=0.011, OR=1.03, 95% CI
(1.008-1.065)] and GENSINI score [ß=0.015, p=0.024,OR=1.012, 95% CI
(1.002-1.028)]  are independent
predictors of POAF. The ROC analysis showed an area under the curve of 0.587 (p=0.012).  GENSINI score of > 50.75 had 82.4%
sensitivity in predicting POAF [p=0.012, 95%CI (0.464-0.711)].

Conclusion: Our results showed
that GENSINI score is an independent predictor of POAF in patients undergoing on-pump CABG surgery.

Anahtar Kelimeler

Atrial fibrillation, coronary artery bypass grafting, gensini score

Gensini skoru pompa destekli koroner arter baypas greftleme sonrasi gelişen atriyal fibrilasyonun öngördürücüsüdür

Öz

Amaç: Postoperatif
atriyal fibrilasyon (POAF), koroner arter baypas cerrahisi (CABG) sonrası
sıktır ve istenmeyen olaylarla ilişkilidir. GENSINI skoru anjiyografik
aterosklerozu derecelendirmek için yaygın olarak kullanılan bir skorlama
sistemidir. POAF gelişiminin öngörülmesinde GENSINI skorunun rolü daha önce
araştırılmamıştır.

Bu çalışmada pompa
destekli CABG yapılan hastalarda POAF gelişiminin öngörülmesinde GENSINI
skorunun rolünün değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntemler: Tek
merkezde gerçekleştirilen bu retrospektif çalışmaya dışlama kriterleri olmayan
113 hasta dahil edildi. Demografik ve klinik özellikleri kaydedildi. GENSINI
skorları hesaplandı. Postoperatif atriyal fibrilasyon gelişimi
öngördürücülerini belirlemek amacıyla tek değişkenli ve çok değişkenli lojistik
regresyon analizi yapıldı.

Bulgular: Hastaların
%30’ unda POAF gelişti. Çok değişkenli lojistik regresyon analizinde C-Reaktif Protein
[ß=0.037, p=0.011, OR=1.03, 95% CI (1.008-1.065)] ve GENSINI skorunun [ß=0.015,
p=0.024,OR=1.012, 95% CI (1.002-1.028)] 
Postoperatif atriyal fibrilasyon gelişiminin bağımsız öngördürücüleri
olarak bulundu. Alıcı işletim karakteristiği (ROC) analizinde eğri altında kalan
alan GENSINI skoru için 0.587 olarak hesaplandı. GENSINI skorunun 50.75’ in
üzerinde olmasının POAF gelişiminin öngörülmesinde  % 82.4 duyarlılığa sahip olduğu saptandı
[p=0.012, 95%CI (0.464-0.711) ].

Sonuç: Çalışmamızda
GENSINI skorunun pompa destekli bypass cerrahisi uygulanan hastalarda POAF
gelişiminin bağımsız bir öngördürücüsü olduğu bulunmuştur.

Anahtar Kelimeler

Atriyal fibrilasyon, koroner arter baypas greftleme, gensini skoru

Kaynakça

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