Alopesi areata ve 25(OH) vitamin D

Yıl 2020, Cilt: 11 Sayı: 4, 220 - 224, 30.09.2020

Erdinç Terzi

https://doi.org/10.18663/tjcl.756143

Öz

Aim:To evaluate the status of serum 25-hydroxyvitamin D(25(OH)D) in patients with AA,serum 25(OH) D concentrations were compared with AA patients and healthy controls and thus determine if a possible association exists between serum 25(OH) D levels and AA.
Materials and Methods:The study comprising 43 patients diagnosed with AA and 69 healthy controls was conducted between October 2017 and March 2018.The serum vitamin D levels of the study group were determined by high performance liquid chromatography.Serum levels of calcium,phosphorus,alkaline phosphatase, and parathyroid hormone were also evaluated.
Results:The study was based on 43 patients aged between 10 and 47 (mean:33,41±7,2).The control group included 69 healthy persons aged between 18 and 55 (mean:33,53±7,2).Serum 25(OH)D levels in patients with AA ranged from 3,7 to 43,5 ng/ml with a mean of 20,21 ng/ml. Serum 25(OH)D levels in healthy controls ranged from 3 to 69,2 ng/ml with a mean of 24,09 ng/ml.There was no statistically difference in the serum vitamin D level between AA patients and healthy controls(p> 0.05)
Conclusion: In the light of these results, no relationship was found between AA and serum 25 (OH) vitamin D.

Anahtar Kelimeler

Alopecia areata, 25(OH) Vitamin D, liquid chromatography

Alopesi areata ile serum 25(OH) d vitamini ilişkisi

Öz

Amaç:Alopesi areata(AA) hastalarında serum 25-hidroksivitamin D (25 (OH) D) seviyelerini incelemek ve sağlıklı bireylerden oluşan kontrol grubu ile karşılaştırarak serum 25 (OH) D seviyeleri ile AA arasında olası bir ilişki olup olmadığı belirlemektir.
Gereç ve Yöntemler: Ekim 2017-Mart 2018 tarihleri arasında AA tanısı konulan 43 hasta ve 69 sağlıklı birey çalışmaya alındı.Çalışma grubunun serum D vitamini düzeyleri yüksek performans likit kromatografi yöntemi ile değerlendirildi.Ayrıca serum kalsiyum, fosfor, alkalen fosfataz ve paratiroid hormon seviyeleri de değerlendirildi.
Bulgular: Çalışmamıza 10-47 yaş(ortalama: 33.41 ± 7.2) arasındaki 43 hasta ve kontrol grubunda 18-55 yaş arası(ortalama: 33,53 ± 7.2). 69 sağlıklı birey katılmıştır. AA'lı hastalarda serum 25 (OH) D seviyeleri ortalama 20,21 ng / ml (3,7-43,5 ng / ml) olarak belirlendi. Kontrol grubunda ise serum 25 (OH) D seviyeleri ortalama 24,09 ng /ml(3-69,2 ng / ml) olarak belirlendi.. Her iki grup arasında serum D vitamini düzeyi arasında istatistiksel olarak anlamlı bir fark yoktu(p> 0.05).
Sonuç: Bu sonuçlar ışığında AA ile serum 25(OH) D vitamini arasında herhangi bir ilişki saptanmamıştır.

Anahtar Kelimeler

Alopesi areata, 25(OH) D vitamini, likit kromatografi

Kaynakça

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