Türkiye’nin Doğusunda Gastrointestinal Şikayeti Olan Erişkinlerde Helicobacter pylori Prevalansının Yaş Gruplarına Göre Dağılımı

Öz

Helicobacter pylori (H. pylori), yaygın bir bakteri olup yaklaşık olarak Dünya nüfusunun %50’sinin bu bakteri ile infekte olduğu tahmin edilmektedir. Esas rezervuarı insandır. H. pylori, kronik antral gastritin sebebi olan peptik ülserlerin önemli bir etkeni olarak bilinmektedir. Bu nedenle çalışmada Türkiye’nin doğusunda gastrointestinal şikayetler ile hastaneye başvuran erişkin bireylerde H. pylori seroprevalansını ve yaş ile ilişkisini saptamak amaçlanmıştır. Bu amaçla hastanemize karın ağrısı, dispeptik yakınmalar, epigastrik hassasiyet, üst abdomende ağrı veya sızı, şişlik ve reflü gibi gastroentestinal şikayetler ile başvuran toplam 993 erişkin yaş grubundaki hastalar çalışma kapsamına alındı. On altı yaş ve üzeri hastalardan alınan kan örneklerinde H. pylori IgG seroprevalansı araştırıldı. Hastalardan alınan serum örnekleri H. pylori IgG kitleri ve TKA 4HD EIA cihazı kullanılarak değerlendirildi. Başvuran hastaların 539 (%54.3)’u kadın, 454 (%45.7)’ü de erkek olup yaş ortalamaları da 39.2 ± 14.0 (16-92) idi. H.Pylori pozitif olan hastaların yaş ortalaması ise 39.7 ± 13.9 (16-92) olarak saptandı. H.pylori IgG total seropozitiflik oranı %67.7 olup bu oran kadınlarda %66.6, erkeklerde ise %68.1 idi. İstatistik! olarak yaş ve cins arasındaki ilişki değerlendirildiğinde anlamlı bir fark saptanmadı (p> 0.05). Muhammet Güzel KURTOĞLU, Hamza BOZKURT, Gülhan ARVAS, Mustafa BERKTAŞ,

Distrubution of Helicobacter pylori Prevalence in Adults with Gastrointestinal Complaints According to Age Levels in Eastern Turkey

Öz

H.pylori is a common bacterium, and approximately 50 percent of the world’s population has been estimated to be infected. Human are the principal reservoir. H.pylori is known as one of important factors in the peptic ulcer, causing antral type chronic gastritis. So, it was aimed in the study to determine the relationship of the gastrointestinal complaints witnessed in Eastern Turkey with H.pylori seroprevalance in adults applying to the hospitals and the age level. A total of 993 adults applying to Medical School Hospital of Van Yüzüncü Yıl University and Van Training and Research Hospital between July 2002 and December 2003 with the complaints of abdominal pain, dis-peptic symptoms, epigastric tenderness, pain or epigastric burning in the upper abdomen, meteorism and other gastrointestinal (GI) complaints such as reflux were enrolled into the study. H.pylori IgG seroprevalance was investigated in the blood samples isolated from the adults at and over 16 years of age. Serum samples obtained from the patients were examined by using TKA 4HD EIA device and H.pylori IgG kits. Of the patients, 539 were females (54.3%) and 454 were males (45.7%). Average age rate was 39.7 ± 13.9 (16-92) in the patients with H.pylori positive. Average age rate was detected as 39.2 ± 14.0 (16-92) in all patients. Total seropositivity rate of H.pylori IgG was 67.7%, and this rate was 66.6 % in men and 68.1 % in women. Evaluating the scores related to the age and sex, no statistically significant difference could be determined according to the age or sex (p> 0.05). Muhammet Güzel KURTOĞLU, Hamza BOZKURT, Gülhan ARVAS, Mustafa BERKTAŞ,

Anahtar Kelimeler

• H.pylori
• seroprevalance
• dispeptic complaints

Kaynakça

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