Down Sendromlu Bir Olguda Anestezik Yaklaşımımız

Öz

Down sendromu (Trizomi 21), dünyada en sık rastlanan genetik bozukluktur ve 1000 canlı doğumdan biri etkilenir. Down sendromlu hastaların organ sistemlerinin yaklaşık tümü birçok kon-jenital anomali ile etkilenir. Down sendromlu birçok hasta yaşamlarının ileri dönemlerinde genel anestezi gerektiren çeşitli işlemlere genellikle ihtiyaç duyarlar. Down sendromlu hastaların preo-peratif değerlendirilmesinde, sistemlerde sıklıkla görülen anomaliler ve bu anomalilerin sonucunda oluşan fonksiyonel şartlara dikkat etmek önemlidir. Bu hastalarda anestezi riski artmıştır. Bu sunuda sendroma anestetik yaklaşım gözden geçirilmiştir. Dr. Vildan TAŞPINAR, Dr. Bahattin NAZLI, Dr. Havva KOÇ, Dr. Peren ÖZER, Dr. Bayazit DİKMEN

Anahtar Kelimeler

• Down sendromu
• anestezi
• DOWN

Anesthetic Considerations for Patients with Down Syndrome: Case Report

Öz

Down syndrome, trisomy 21, is the most prevalent genetic disorder worldwide and affects more than 1 in 1000 live births. Patients with Down syndrome are afflicted with multiple congenital anomalies that affect almost all of their organ systems. Later in life many patients with Down syndrome often require multiple procedures requiring general anesthesia. During preoperative evaluation for anesthesia in the Down patient, it is important to focus attention on the functional conditions of the patient and systems that frequently show anomalies. The risks of anesthesia are increased in these patients. In this report the anesthetic implications of the syndrome are reviewed.

Anahtar Kelimeler

• Down syndrome
• anesthesia
• down

Kaynakça

1. 1. Morgan GE, Mikhail MS, Murray MJ, Larson CP. Pediatric Anesthesia. In: Ryan JF. Clinical Anesthesiology. 3rd ed. USA: McGraw-Hill Companies; 2002. p. 868.
2. 2. Miller RD. Anesthetic Implications of Concurrent Diseases. In: Roizen MF, Fleisher LA eds. Miller’s Anesthesia. 6th ed. New York: Churchill Livingstone; 2005. p. 1099.
3. 3. Miller RD. Anesthesia for Eye, Ear, Nose, and Throat Surgery. In: Donlon JV, Doyle DJ, Feldman MA, eds. Miller’s Anesthesia. 6th ed. New KAYNAKLAR York: Churchill Livingstone; 2005. p. 2536.
4. 4. Santamaria LB, Di Paola C, Mafrica F, Fodale V. Preanesthetic Evaluation and Assessment of Children with Down’s Syndrome. Scientific World Journal 2007; 7:242-51.
5. 5. Shott SR. Down Syndrome: Common Otolaryngologic Manifestations. Am J Med Genet C Semin Med Genet 2006 ;142(3):131-40.
6. 6. Arkan A. Özel Durumlar. Arkan A. Çocuk Anestezisi. Birinci Baskı. İzmir: İzmir Çağdaş Matbaa ve Ambalaj: 1994. s. 188.
7. 7. Borland LM, Colligan J, Brandom BW. Frequency of Anesthesia-Related Complications in Children with Down Syndrome Under General Anesthesia for Noncardiac Procedures. Paediatr Anaesth 2004 ;14(9):733-8.
8. 8. Infosino A. Pediatric Upper Airway and Congenital Anomalies. Anesthesiol Clin North America 2002 ;20(4):747-66.

9. 9. Gregory GA. Psychological Preparation and Premedication. In: Steward DJ. Pediatric Anesthesia. 2nd ed. New York: Churchill Livingstone; 1989. p. 529.