TR
EN
Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study
Öz
Objective: Melanocytic nevi are among the most common benign growths of melanocytes. Although usually benign, these lesions are frequently excised for a variety of clinical and patient-centered indications, including aesthetic concerns, fear of malignancy, symptomatic lesions, physical interference, or patient preference.
This study aims to define the indications for nevus excision, systematically evaluate patient-reported outcomes, optimize surgical decision-making, improve therapeutic planning, and contribute to advancing individualized, patient-centered care in plastic surgery.
Methods: This study was designed as a prospective observational study. The study was conducted in the same clinical setting between August 2025 and October 2025. A total of 154 adult patients aged 18 to 85 years were included in the study. For each excised nevus, indications, histopathological diagnoses, and patient satisfaction were recorded for each excision. Satisfaction was evaluated at >1 month follow-up using a Numeric Rating Scale (NRS 1–10).
Results: The median age of patients was 35 (IQR: 28–45). The majority of procedures (n=169, 65.8%) were conducted for aesthetic reasons. Pathology revealed that 181 cases (70.4%) were intradermal nevi. Overall clinicopathological concordance was 81.7%. The lowest satisfaction was observed in cosmetic excisions (mean score: 8.38±1.78), while the highest was noted in excisions performed due to patient fear of malignancy (mean score: 9.63±0.96) (p = 0.007).
Conclusion: While nevus excision yields high overall satisfaction, scores are lower in aesthetic cases; thus, comprehensive preoperative counseling is essential to align patient expectations with surgical outcomes.
Anahtar Kelimeler
Etik Beyan
Ethical approval was obtained for this research from the Medical Research Scientific and Ethical Evaluation Board No. 2 of Ankara
Bilkent City Hospital (date: 06/08/2025, decision no: 2-25-1286).
Kaynakça
- Aysal, B. K., Çolak, Ö., Taşkın, S., Gürel, Z. Ö., Yasak Par, T., & Üsçetin, İ. (2022). Histopathological analysis of nevi excisions in our clinic. European Archives of Medical Research, 38(4), 295–298. https://doi.org/10.4274/eamr.galenos.2022.08108
- Barnhill, R., Piepkorn, M., & Busam, K. (2004). Pathology of melanocytic nevi and malignant melanoma (2nd ed.). Springer. https://doi.org/10.1007/978-0-387-21619-5
- Black, S., Rutty, G. N., Hainsworth, S. V., & Mallett, X. (2014). The incidence and position of melanocytic nevi for the purposes of forensic image comparison. International Journal of Legal Medicine, 128(3), 535–543. https://doi.org/10.1007/s00414-013-0821-z
- Bodman, M. A., & Al Aboud, A. M. (2025). Melanocytic nevi. In StatPearls. StatPearls Publishing.
- Bong, J. L., & Perkins, W. (2003). Shave excision of benign facial melanocytic naevi: A patient’s satisfaction survey. Dermatologic Surgery, 29(3), 227–229. https://doi.org/10.1046/j.1524-4725.2003.29054.x
- Dung, P. T. V., Son, T. T., Thuy, T. T. H., & Duy, T. T. (2023). Serial excision surgery for giant dorsal congenital melanocytic nevus: Case report. International Journal of Surgery Case Reports, 106, Article 108152. https://doi.org/10.1016/j.ijscr.2023.108152
- Ferrandiz, L., Moreno-Ramirez, D., Camacho, F. M., & Rios-Martin, J. J. (2005). Shave excision of common acquired melanocytic nevi: Cosmetic outcome, recurrences, and complications. Dermatologic Surgery, 31(9), 1112–1115. https://doi.org/10.1097/00042728-200509000-00005
- Frischhut, N., Kofler, L., Kofler, H., & Duschet, P. (2022). The spectrum of melanocytic nevi and their clinical implications. Journal der Deutschen Dermatologischen Gesellschaft, 20(4), 483–504. https://doi.org/10.1111/ddg.14776
Ayrıntılar
Birincil Dil
İngilizce
Konular
Plastik, Rekonstrüktif ve Estetik Cerrahi
Bölüm
Araştırma Makalesi
Yayımlanma Tarihi
27 Ağustos 2026
Gönderilme Tarihi
21 Mayıs 2026
Kabul Tarihi
22 Temmuz 2026
Yayımlandığı Sayı
Yıl 2026 Cilt: 11 Sayı: 3
APA
Mafratoğlu, U. T., Ergani, H. M., İnce, V., Korur, S. A., & Ünlü, R. E. (2026). Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study. Turkish Medical Journal, 11(3), 94-101. https://doi.org/10.70852/tmj.1956246
AMA
1.Mafratoğlu UT, Ergani HM, İnce V, Korur SA, Ünlü RE. Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study. TMJ. 2026;11(3):94-101. doi:10.70852/tmj.1956246
Chicago
Mafratoğlu, Umut Tahsin, Hasan Murat Ergani, Vural İnce, Seyit Ahmet Korur, ve Ramazan Erkin Ünlü. 2026. “Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study”. Turkish Medical Journal 11 (3): 94-101. https://doi.org/10.70852/tmj.1956246.
EndNote
Mafratoğlu UT, Ergani HM, İnce V, Korur SA, Ünlü RE (01 Ağustos 2026) Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study. Turkish Medical Journal 11 3 94–101.
IEEE
[1]U. T. Mafratoğlu, H. M. Ergani, V. İnce, S. A. Korur, ve R. E. Ünlü, “Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study”, TMJ, c. 11, sy 3, ss. 94–101, Ağu. 2026, doi: 10.70852/tmj.1956246.
ISNAD
Mafratoğlu, Umut Tahsin - Ergani, Hasan Murat - İnce, Vural - Korur, Seyit Ahmet - Ünlü, Ramazan Erkin. “Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study”. Turkish Medical Journal 11/3 (01 Ağustos 2026): 94-101. https://doi.org/10.70852/tmj.1956246.
JAMA
1.Mafratoğlu UT, Ergani HM, İnce V, Korur SA, Ünlü RE. Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study. TMJ. 2026;11:94–101.
MLA
Mafratoğlu, Umut Tahsin, vd. “Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study”. Turkish Medical Journal, c. 11, sy 3, Ağustos 2026, ss. 94-101, doi:10.70852/tmj.1956246.
Vancouver
1.Umut Tahsin Mafratoğlu, Hasan Murat Ergani, Vural İnce, Seyit Ahmet Korur, Ramazan Erkin Ünlü. Indications, Histopathological Correlation, and Patient-Reported Outcomes in Nevus Excision: A Prospective Observational Study. TMJ. 01 Ağustos 2026;11(3):94-101. doi:10.70852/tmj.1956246