A child with bradycardia and hypotension related to mad honey intoxication

Öz

Mad honey poisoning is a well known condition in the Black Sea Region of Turkey The cause of the poisoning is the toxin known as grayanotoxin found in honey obtained from the nectar of Rhododendron ponticum species growing naturally on the mountains in the region Here in we presented a 15 year old boy was brought to the emergency department with weakness and dizziness due to bradycardia and hypotension after eating mad honey Turk Arch Ped 2013; 48: 53 4

Anahtar Kelimeler

• Child, intoxication, mad honeyDO I: 10.4274/tpa.328

Deli bal zehirlenmesine bağlı bradikardi ve hipotansiyon gelişen çocuk olgusu

Öz

Deli bal zehirlenmesi Türkiye rsquo;nin Karadeniz Bölgesi rsquo;nde görülen bir durumdur Bu zehirlenmenin nedeni bölgedeki dağlarda doğal olarak yetişen Rhododendron ponticum bitki türünün nektarından elde edilen balda bulunan grayanotoksin diye bilinen toksinden kaynaklanır Burada bal yedikten sonra kan basıncı düşüklüğü ve bradikardi nedeniyle gelişen halsizlik ve baş dönmesi yakınmaları ile acil servise getirilen 15 yaşındaki bir erkek çocuk sunuldu.

Anahtar Kelimeler

• Çocuk
• deli bal
• zehirlenme

Kaynakça

1. Onat FY, Yegen BC, Lawrence R, Oktay A, Oktay S. Mad honey poisoning in man and rat. Rev Environ Health 1991; 9: 3-9.
2. Seyama I, Yamaoka K, Yakehiro M, Yoshioka Y, Morihara K. Is the site of action of grayanotoxin the sodium channel gating of squid axon? Jpn J Physiol 1985; 35: 401-10.
3. Maejima H, Kinoshita E, Seyama I, Yamaoka K. Distinct site regulating grayanotoxin binding and unbinding to D4S6 of Nav1.4 sodium channel as revealed by improved estimation of toxin sensitivity. J Biol Chem 2003; 278: 9464-71.
4. Onat F, Yegen BC, Lawrence R, Oktay A, Oktay S. Site of action of grayanotoxins in mad honey in rats. J Appl Toxicol 1991; 11: 199-201. Ergun K, Tufekcioglu O, Aras D, Korkmaz S, Pehlivan S. A rare cause of atrioventricular block: mad honey intoxication. Int J Cardiol 2005; 99: 347Wong J, Youde E, Dickinson B, Hale M. Report of the Rhododendron feasibility study. School of agricultural and forest sciences üniversity of wales, Bangor Gwynedd LL57 2UW UK, 2002: 73.
5. Ozhan H, Akdemir R, Yazici M, Gündüz H, Duran S, Uyan C. Cardiac emergencies caused by honey ingestion: a single centre experience. Emerg Med J 2004; 21: 742-4. Türk Ped Arfl 2013; 48: 53-4 Turk Arch Ped 2013; 48: 53-4 Uzun ve ark.
6. Deli bal zehirlenmesine bağlı bradikardi ve hipotansiyon gelişen çocuk olgusu / A child with bradycardia and hypotension related to mad honey intoxication 54