Neonatal mortality and short term prognosis in newborns born after assisted reproduction techniques

Abstract

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Keywords

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Yardımcı üreme teknikleri ile sağlanan gebeliklerden doğan bebeklerde yenidoğan ölüm oranı ve kısa dönemdeki seyri

Öz

Amaç: Günümüzde yard›mc› üreme tekniklerinin (YÜT) kullan›m›n›n artmas› ile birlikte, bu gebeliklere ba¤l› erken do¤um ve ço¤ul gebelik oranlar› da artm›flt›r. Bu çal›flmada, klini¤imizde YÜT ile sa¤lanan gebeliklerden do¤an bebeklerdeki yenido¤an hastal›k ölüm oran› ve k›sa dönem seyrin araflt›r›lmas› amaçlanm›flt›r.

Gereç ve Yöntem: Hastanemizde Ocak 2007-Aral›k 2007 tarihleri aras›nda YÜT ile gerçeklefltirilen gebeliklerden do¤an 123 bebek çal›flma grubu olarak al›nd›. Olgular›n dosyalar›ndan geriye dönük olarak perinatal ve yenido¤an döneme ait verileri, do¤ufltan anomali varl›¤›, erken do¤uma ba¤l› hastal›klar (kronik akci¤er hastal›¤›, kafa içine kanama, prematüre retinopatisi) ve yenido¤an ölüm oran›n›n sonuçlar› kaydedildi. Kaybedilen olgularda ölüme neden olan etkenler araflt›r›larak, YÜT bebeklerindeki seyir normal gebeliklerden do¤an bebeklerle de istatistiksel olarak karfl›laflt›r›ld›. ‹statistiksel analizlerde ba¤›ms›z örnekler için t-testi ve ki-kare testi kullan›ld›.

Bulgular: Çal›flma grubunu oluflturan 123 YÜT bebe¤inin %95,6’s› erken do¤mufltu ve ölüm oran› % 20,3 idi. Çal›flma grubunda do¤ufltan anomali s›kl›¤› %8,9, ço¤ul gebelik oran› %90,2 olarak bulundu. Normal gebeliklere göre YÜT bebeklerinde do¤um a¤›rl›¤›n›n daha düflük, ölüm oran›n›n ve do¤ufltan anomali s›kl›¤›n›n daha yüksek oldu¤u saptand›.

Çıkarımlar: Yard›mc› üreme teknikleri sonras›nda do¤an bebeklerde ço¤ul gebelik, düflük do¤um a¤›rl›¤› ve do¤ufltan anomali oran›n›n artm›fl oldu¤u, bu durumun hastal›k ve ölüm oran›nda art›fla neden oldu¤u kan›s›na var›lm›flt›r. 

Anahtar Kelimeler

• Erken doğmuş bebek
• yardımcı üreme teknikleri
• yenidoğan ölüm oranı

Kaynakça

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