Avian influenza – Review

Abstract

Recent spread of avian influenza A H5N1 virus to poultry and wild birds has increased the threat of human infections with H5N1 virus worldwide In this review the epidemiology virolgy clinical and laboratory characteristics and management of avian influenza is described The virus has demonsrated considerable pandemic potential and is the most likely candidate of next pandemic threat For pandemic preparedness stockpiling antiviral agents and vaccination are the most important intervention measurements Turk Arch Ped 2007; 42: 46 51 Key words: Avian influenza A bird poultry pandemy

Keywords

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Kuş gribi Derleme

Öz

Avian influenza A H5N1 virüsünün son yıllarda kuşlar ve kümes hayvanlarında hızlıca yayılması tüm dünyada insanlarda hastalık açısından tehdit oluşturmaktadır Bu yazıda aviaren influenza virüsünün epidemiyolojisi virolojisi klinik özellikleri ve tedavisi ele alınmaktadır H5N1 virüsü ciddi pandemilere yol açabilir ve olası bir pandemi için en kuvvetli aday olarak görülmektedir Pandemi hazırlığında en önemli iki önlem antiviral ilaçların stok edilmesi ve aşılamadır Türk Ped Arş 2007; 42: 46 51 Anahtar kelimeler: Avian influenza A kuş kümes hayvanı pandemi

Anahtar Kelimeler

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Kaynakça

1. Harder TC, Werner O. Avian Influenza. In: Kamps BS, Hoff- mann C, Preise W (eds). Influenza Report 2006: 48-87. http://www.influenzareport.com/influenzareport2006.
2. Hien TT, de Jong M, Farrar J. Avian influenza-a challenge to global health care structures. N Engl J Med 2004; 351: 2363-5.
3. Jong MD, Hien TT. Avian influenza A (H5N1). J Clin Virol 2006; 35: 2-13.
4. Beigel JH, Farrar J, Han AM, et al. Avian influenza A (H5N1) infection in humans. N Engl J Med 2005; 353:1374-85.
5. Wong SS, Yuen KY. Avian influenza virus infections in hu- mans. Chest 2006; 129: 156-68.
6. Webster RG, Govorkova EA. H5N1 influenza-continuing evo- lution and spread. N Engl J Med 2006; 355: 2174-7.
7. Fouchier RA, Munster V, Wallensten A, et al. Characterization of a novel influenza A virus hemagglutinin subtype (H16) ob- tained from black-headed gulls. J Virol 2005; 79: 2814-22.
8. Couceiro JN, Paulson JC, Baum LG. Influenza virus strains selectively recognize sialyloligosaccharides on human respi- ratory epithelium; the role of the host cell in selection of he- magglutinin receptor specificity. Virus Res 1993; 29: 155-65.

9. Ito T, Couceiro JN, Kelm S, et al Molecular basis for the ge- neration in pigs of influenza A viruses with pandemic potenti- al. J Virol 1998; 72: 7367-73.
10. Drake JW. Rates of spontaneous mutation among RNA viru- ses. Proc Natl Acad Sci U S A 1993; 90: 4171-5.
11. Webster RG, Hulse DJ. Microbial adaptation and change: avi- an influenza. Rev Sci Tech 2004; 23: 453-65.
12. Johnson NP, Mueller J. Updating the accounts: global morta- lity of the 1918-1920 "Spanish" influenza pandemic. Bull Hist Med 2002; 76: 105-15.
13. Perroncito CE. [it. Typhoid epizootic in gallinaceous birds.] Epizoozia tifoide nei gallinacei. Torino: Annali Accademia Ag- ricoltura 1878; 21:87-126.
14. Chan PK. Outbreak of avian influenza A (H5N1) virus infection in Hong Kong in 1997. Clin Infect Dis 2002; 34 Suppl 2: 58-64.
15. Chotpitayasunondh T, Ungchusak K, Hanshaoworakul W, et al. Human disease from influenza A (H5N1), Thailand, 2004. Emerg Infect Dis 2005; 11: 201-9.
16. Hien TT, Liem NT, Dung NT, et al. Avian influenza A (H5N1) in 10 patients in Vietnam. N Engl J Med 2004; 350: 1179-88.
17. Chotpitayasunondh T, Ungchusak K, Hanshaoworakul W, et al. Human disease from influenza A (H5N1), Thailand, 2004. Emerg Infect Dis 2005; 11: 201-9.
18. Oner AF, Bay A, Arslan S, et al. Avian influenza A (H5N1) in- fection in eastern Turkey in 2006. N Engl J Med 2006; 355: 2179-85.
19. To KF, Chan PK, Chan KF, et al. Pathology of fatal human in- fection associated with avian influenza A H5N1 virus. J Med Virol 2001; 63: 242-6.
20. Couceiro JN, Paulson JC, Baum LG. Influenza virus strains selectively recognize sialyloligosaccharides on human respi- ratory epithelium; the role of the host cell in selection of he- magglutinin receptor specificity. Virus Res 1993; 29: 155-65.
21. Ito T, Couceiro JN, Kelm S, et al. Molecular basis for the ge- neration in pigs of influenza A viruses with pandemic potenti- al. J Virol 1998; 72: 7367-73.
22. Gambaryan AS, Tuzikov AB, Bovin NV, et al. Differences bet- ween influenza virus receptors on target cells of duck and chicken and receptor specificity of the 1997 H5N1 chicken and human influenza viruses from Hong Kong. Avian Dis 2003; 47: 1154-60.
23. Shinya K, Ebina M, Yamada S, Ono M, Kasai N, Kawaoka Y. Avian flu: influenza virus receptors in the human airway. Natu- re 2006; 440: 435-56.
24. Bridges CB, Lim W, Hu-Primmer J, et al. Risk of influenza A (H5N1) infection among poultry workers, HongKong, 1997–1998. J Infect Dis 2002;185:1005–10.
25. Katz JM, Lim W, Bridges CB, et al. Antibody response in indi- viduals infected with avian influenza A (H5N1) viruses and de- tection of anti-H5 antibody among household and social con- tacts. J Infect Dis 1999; 180: 1763–70.
26. Apisarnthanarak A, Erb S, Stephenson I, et al. Seroprevalen- ce of anti-H5 antibody among Thai health care workers after exposure to avian influenza (H5N1) in a tertiary care center. Clin Infect Dis 2005; 40: 16–8.
27. Liem NT, Lim W. World Health Organization International Avi- an Influenza Investigation Team, Vietnam. Lack of H5N1 avi- an influenza transmission to hospital employees, Hanoi, 2004. Emerg Infect Dis 2005; 11: 210–5.
28. Schultsz C, Dong VC, Chau NV, et al. Avian influenza H5N1 and healthcare workers. Emerg Infect Dis 2005; 11: 1158–9.
29. Du Ry van Beest Holle M, Meijer A, Koopmans M, de Jager CM. Human-to-human transmission of avian influenza A/H7N7, The Netherlands, 2003. Euro Surveill 2005; 10: 264-8.
30. Zyl GV. Laboratory findings. In: Kamps BS, Hoffmann C, Pre- ise W (eds). Influenza Report. Flying publisher 2006; 110-27. http://www.influenzareport.com/influenzareport 2006.
31. Uyeki TM. Influenza diagnosis and treatment in children: a re- view of studies on clinically useful tests and antiviral treatment for influenza. Pediatr Infect Dis J 2003; 22: 164-77.
32. Spackman E, Suarez DL. Use of a novel virus inactivation method for a multicenter avian influenza real-time reverse transcriptase-polymerase chain reaction proficiency study. J Vet Diagn Invest 2005; 17: 76-80.
33. Yuen KY, Chan PK, Peiris M, et al. Clinical features and rapid viral diagnosis of human disease associated with avian influ- enza A H5N1 virus. Lancet 1998; 351: 460-1.
34. Schunemann HJ, Hill SR, Kakad M, et al. WHO Rapid Advice Guidelines for pharmacological management of sporadic hu- man infection with avian influenza A (H5N1) virus. Lancet In- fect Dis 2007; 7: 21-31.
35. WHO. Cumulative number of confirmed human cases of avi- an influenza A/(H5N1) reported to WHO; 2006, at http://www.who.int/csr/disease/avian influenza / country /ca- ses-table-2007-01-27/en/index.html
36. Butler D. Alarms ring over bird flu mutations. Nature 2006; 439: 248-9.
37. Murray CJ, Lopez AD, Chin B, Feehan D, Hill KH. Estimation of potential global pandemic influenza mortality on the basis of vital registry data from the 1918-20 pandemic: a quantita- tive analysis. The Lancet 2006; 368: 2211-8.
38. Congressional Budget Office. A potential influenza pandemic: possible macroeconomic effects and policy issues. December 8, 2005. (Accessed at http://www.dhhs.state.nh.us/DHHS/LIB- RARY/Research/avian-cbo-economy.htm.
39. Treanor JJ, Campbell JD, Zangwill KM, et al. Safety and Im- munogenicity of an Inactivated Subvirion Influenza A (H5N1) Vaccine. N Eng J Med 2006; 354: 1343-51.
40. Poland GA. Vaccines against avian influenza-a race against time. N Eng J Med 2006; 354: 1411-3.