The effect of recurrent urinary tract infections on somatic growth in children Preliminary study Original Article

Yıl 2008, Cilt: 43 Sayı: 4, 39 - 42, 01.12.2008

Ahmet Keskinoğlu Sevgi Mir

Öz

Aim: Urinary tract infection is one of the common bacterial infections in children and may lead to substantial morbidity In this study the effect of recurrent urinary tract infections on the growth of children aged between 0 12 years was investigated nbsp; nbsp; nbsp; Material and Method: In this prospective study 72 children who had the definite diagnosis of recurrent urinary tract infections and followed up for at least 6 months in a period of one year in the outpatient clinic of nephrology were included The infection was evaluated with urine culture and growth charts nbsp; Data were analyzed with Pearson and Mc Nemar chi square tests t test Mann Whitney U test and corelation analysis Results: The mean age of the children was 42 9 months 66 7 of those were females Height for age and weight for age were found to be lower in 16 7 and 22 2 respectively Escherischia coli was the most common pathogen found in urine cultures Renal scarring was determined in 20 8 of the subjects While the attack numbers of urinary trcat infections were increasing height and weight measurements for age were significantly decreasing Weight for age was significantly low in boys at the beginning of the study Weight for age score improved after a 6 month follow up period Conclusions: The treatment and the prophylaxy of the recurrent urinary tract infections resulted in a positive effect on growth of the children nbsp; Turk Arch Ped 2008; 43: 139 42 Key words: Child growth recurrent urinary tract infection

Anahtar Kelimeler

-

Çocuklarda tekrarlayan idrar yolu enfeksiyonlarının büyüme üzerine etkisi Ön çalışma Orijinal Araştırma

Öz

Amaç: Tekrarlayan idrar yolu enfeksiyonu sonuçları açısından çocuk sağlığını olumsuz etkileyen önemli bir hastalıktır Bu çalışmada 0 12 yaş çocuklarda tekrarlayan idrar yolu enfeksiyonunun büyüme üzerine etkisi araştırıldı Gereç ve Yöntem: İleriye yönelik bu çalışmaya bir yılda nefroloji polikliğinde tekrarlayan idrar yolu enfeksiyonu tanısı alan en az altı ay izlenen 72 çocuk alındı Enfeksiyon idrar kültürü büyüme Z skoru ile değerlendirildi Veriler Pearson ve nbsp; Mc Nemar ki kare t testi Mann Whitney U testi ve korelasyon analizleriyle çözümlendi Bulgular: Çocukların yaş ortalaması 42 9 ay 66 7’si kız 16 7’sinde yaşa göre boy 22 2’sinde yaşa göre ağırlık düşüktü İdrar kültüründe en sık E coli üredi 20 8’inde böbrekte skar saptandı İdrar yolu enfeksiyonu sayısı arttıkça yaşa ve boya göre ağırlık anlamlı olarak azalmaktaydı Yaşa göre ağırlık başlangıçta erkek çocuklarda anlamlı olarak düşüktü Altı aylık izlemden sonra yaşa göre ağırlık skorunda anlamlı olarak düzelme görüldü Çıkarımlar: Tekrarlayan idrar yolu enfeksiyonun sağaltım ve profilaksi ile kontrolü çocuklarda büyümeyi olumlu etkilemiştir Türk Ped Arş 2008; 43: 139 42 Anahtar kelimeler: Büyüme çocuk tekrarlayan idrar yolu enfeksiyonu

Anahtar Kelimeler

Büyüme, çocuk, tekrarlayan idrar yolu enfeksiyonu

Kaynakça

• Chang SL, Shortliffe LD. Pediatric urinary tract infections. Pediatr Clin N Am 2006; 53: 379-400.
• Sirin A, Emre S, Alpay H, et al. Etiology of chronic renal failure in Turkish children. Pediatr Nephrol 1995; 9: 549-52.
• Marild S, Jodal U. Incidence rate of first-time symptomatic urinary tarct infection in children under 6 years of age. Acta Paediatr 1998; 87: 549-52.
• Conway PH, Cnaan A, Zaoutis T, et al. Recurrent urinary tract infection in children: Risk factros and association with prophylactic antimicrobials. JAMA 2007; 298: 179-86.
• Peru H, Bakkaloglu SA, Soylemezoglu O, Buyan N, Hasanoglu E. The relationship between urinary tarct infections and vesicoureteral reflux in Turkish children. Int Urol Nephrol 2008, June (Epub printing).
• Menon P, Rao KLN, Bhattacharya A, Mahajan JK, Samujh R. Primary vesicoureteral reflux: progress of disease, somatic growth and renal parameters. Indian Pediatrics 2004; 41: 1025-30.
• Sutton R, Atwell JD. Physical growth velocity during conservative treatment and following subsequent surgical treatment for primary vesicoureteral reflux. Br J Urol 1989; 63: 245-50.
• Jantausch B, Kher K. Urinary tract infection. In: Kher KK, Schnaper HW, Makker SP, (eds). Clinical Pediatric Nephrology. Oxon: Informa Healthcare, 2006: 553-73.
• Gokcay G, Furman A, Neyzi O. Updated growth curves for Tur- kish children aged 15 days to 60 months. Child Care Health Dev 2008; Apr 2, (E-pub).
• Guizar JM, Kornhauser C, Malacara JM, Sanchez G, Zamora J. Renal tubular acidosis in children with vesicoureteral reflux. J Urol 1996; 159: 193-5.
• Wingen AM, Koskimies O, Olbing H, Seppanen J, Tamminen- Mobius T. Growth and weight gain in children with vesicoureteral reflux receiving medical versus surgical treatment: 10-year results of a prospective, randomized study. Acta Paediatr 1999; 88: 56-61.
• Polito C, Marte A, Zamparelli M, Papale MR, Rocco CE, La Manna A. Catch-up growth in children with vesico-ureteric reflux. Pediatr Nephrol 1997; 11: 164-8.
• Polito C, La Manna A, Capaccione A, Pullano F, Iovene A, Del Gado R. Height and weight in children with vesicoureteric reflux and renal scarring. Pediatr Nephrol 1996; 10: 564-7.
• Pinter AB, Jaszai V, Dober I. Medical treatment of vesico-ureteral reflux detected in infancy. J Urol 1988; 140: 121-4.
• Stokland E, Hellstrom M, Jacobsson B, Jodal U, Lundgren P, Sixt R. Early 99m-Tc-dimercaptosuccinic acid (DMSA) scintigraphy in symptomatic first-time urinary tract infection. Acta Paediatr 1996; 85: 430-6.