Subacute sclerosing panencephalitis SSPE Invited Editor

Yıl 2008, Cilt: 43 Sayı: 3, 72 - 79, 01.09.2008

Sevim Şahin Serap Uysal

Öz

Subacute sclerosing panencephalitis SSPE is a neurodegenerative disease with a poor prognosis It is characterized by the persistent infection of the brain by the measles virus Mechanisms causing persistence and reactivation of measles virus in SSPE are unknown Patients usually have behavioral changes myoclonus dementia visual disturbances and pyramidal and extrapyramidal signs No treatment has a proven role A decline in frequency has been noticed in most of the developed countries whereas it continues to be high in developing countries Effective immunization against measles is the only solution presently available to the problem of this dreaded disease We aimed to give an overall review on SSPE in this paper Turk Arch Ped 2008; 43: 72 9 Key words: Child measles subacute sclerosing panencephalitis

Anahtar Kelimeler

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Subakut sklerozan panansefalit SSPE Çağrılı Editör

Öz

Subakut sklerozan panansefalit SSPE nörodejeneratif bir hastalıktır Kızamık virüsünün beyinde oluşturduğu süregen enfeksiyon ile belirgindir Virüsün süregenliğinin ve reaktivasyonunun mekanizmaları bilinmemektedir Hastalarda genellikle davranış değişiklikleri miyoklonus demans görme bozukluğu piramidal ve ekstrapiramidal bulgular vardır Hastalığın henüz etkili ve kesin bir tedavisi yoktur Gelişmiş ülkelerde sıklığında azalma olmakla birlikte gelişmekte olan ülkelerde sık görülmektedir Kızamığa karşı etkin aşılama bu hastalık için şu andaki tek çözümdür Bu yazıda SSPE ile ilgili kapsamlı bilgi verilmesi amaçlandı Türk Ped Arş 2008; 43: 72 9 Anahtar kelimeler: Çocuk kızamık subakut sklerozan panansefalit

Anahtar Kelimeler

Çocuk, kızamık, subakut sklerozan panansefalit

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