BENZOKROMON VE BAZI BENZOKUMARİNLERİN ANTİOKSİDANT VE ANTİMİKROBİYAL AKTİVİTELERİ

Yıl 2008, Cilt: 9 Sayı: 2, - , 05.08.2016

Hakan Kolancılar Erkan Mozioğlu

Öz

ANTIMICROBIAL ACTIVITIES OF SOME BENZOCOUMARINES AND BENZOCHROMONE

Öz

Two benzocoumarins (1, 2) and a benzochromone (3) were obtained from the reaction of 2,7 dihydroxynaphthalene and ethyl acetoacetate in the presence of sulphuric acid (95-80 %) as a catalyst. These products were screened in order to assay their antimicrobial activies against standard bacterial strains such as E. coli ATCC 29995, S. S. aureus ATCC 6538P, Mycobacterum smegmatis and the yeast C. albicans ATCC 10239. Neither 1 nor 3 exhibited the antimicrobial activies against standard bacterial strains. The only 2 showed activity against S. S. aureus ATCC 6538P. Also, the antioxidant capacities of the compounds were investigated by using the CUPRAC method.

Anahtar Kelimeler

2, 7-Dihydroxynapthalene, ethyl acetoacetate, benzocoumarin, benzochromone, antimicrobial activity, the CUPRAC method

Kaynakça

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