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High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia

Cilt: 6 Sayı: 3 30 Eylül 2025
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High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia

Öz

Benign transient hyperphosphatasemia (BTH) is a self-limited condition of early childhood, defined by a transient elevation of serum alkaline phosphatase (ALP) without evidence of underlying disease. This report emphasizes the importance of considering BTH in the differential diagnosis of elevated ALP and presents a case in light of the current literature. Recognition of BTH is crucial to prevent unnecessary investigations and referrals in pediatric practice.

Anahtar Kelimeler

Kaynakça

  1. 1. Solé-Enrech G, Cano-Corres R, Nuez-Zaragoza E, Pine- da-Solas V, Berlanga-Escalera E. Benign transient hyperp- hosphatasemia: Two case reports. Clin Biochem. 2021 May;91:67-69. doi: 10.1016/j.clinbiochem.2021.01.015. Epub 2021 Feb 9. PMID: 33571512.
  2. 2. Sakurai Y, Higashiguchi T. Transient hyperphosphatase- mia: Possible association with pediatric acute respiratory infection. Pediatr Investig. 2021 Jun 18;5(2):94-98. doi: 10.1002/ped4.12265. PMID: 34179704; PMCID: PMC8212759.
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  4. 4. Kraut JR, Metrick M, Maxwell NR, Kaplan MM. Iso- enzyme studies in transient hyperphosphatasemia of infancy. Ten new cases and a review of the literature. Am J Dis Child. 1985 Jul;139(7):736-40. doi: 10.1001/archpedi.1985.02140090098042. PMID: 4014098.
  5. 5. Chu AS, Rothschild JG. Update on Benign Transient Hyperphosphatasemia: Recognizing an Underappreciated Condition. Clin Pediatr (Phila). 2016 Jun;55(6):564-6. doi: 10.1177/0009922815593908. Epub 2015 Jul 7. PMID: 26156974.
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  7. 7. Shkalim Zemer V , Hoshen M, Levinsky Y , Richenberg Y , Yosef N, Oberman B, et al. Benign transient hyperphospha- tasemia in infants and children: a retrospective database study. Eur J Pediatr. 2023 Jul;182(7):3211-3216. doi: 10.1007/s00431-023-04995-1. Epub 2023 May 2. PMID: 37127797; PMCID: PMC10151212.
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Ayrıntılar

Birincil Dil

İngilizce

Konular

Bebek ve Çocuk Sağlığı, Çocuk Endokrinolojisi

Bölüm

Olgu Sunumu

Yayımlanma Tarihi

30 Eylül 2025

Gönderilme Tarihi

18 Ağustos 2025

Kabul Tarihi

23 Eylül 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 6 Sayı: 3

Kaynak Göster

APA
Tekin, S. C., & Kasap, T. (2025). High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia. Troia Medical Journal, 6(3), 97-99. https://doi.org/10.55665/troiamedj.1767889
AMA
1.Tekin SC, Kasap T. High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia. Troia Med J. 2025;6(3):97-99. doi:10.55665/troiamedj.1767889
Chicago
Tekin, Samet Can, ve Tolga Kasap. 2025. “High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia”. Troia Medical Journal 6 (3): 97-99. https://doi.org/10.55665/troiamedj.1767889.
EndNote
Tekin SC, Kasap T (01 Eylül 2025) High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia. Troia Medical Journal 6 3 97–99.
IEEE
[1]S. C. Tekin ve T. Kasap, “High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia”, Troia Med J, c. 6, sy 3, ss. 97–99, Eyl. 2025, doi: 10.55665/troiamedj.1767889.
ISNAD
Tekin, Samet Can - Kasap, Tolga. “High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia”. Troia Medical Journal 6/3 (01 Eylül 2025): 97-99. https://doi.org/10.55665/troiamedj.1767889.
JAMA
1.Tekin SC, Kasap T. High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia. Troia Med J. 2025;6:97–99.
MLA
Tekin, Samet Can, ve Tolga Kasap. “High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia”. Troia Medical Journal, c. 6, sy 3, Eylül 2025, ss. 97-99, doi:10.55665/troiamedj.1767889.
Vancouver
1.Samet Can Tekin, Tolga Kasap. High alkaline phosphatase level in a healthy child: A case of benign transient hyperphosphatasemia. Troia Med J. 01 Eylül 2025;6(3):97-9. doi:10.55665/troiamedj.1767889