Asymptomatic ovarian metastasis of malignant melanoma in an adolescent

Öz

Malignant Melanoma (MM) is a tumor with an extremely poor prognosis and is very rare in adolescents. The prognosis of the disease in this population is different from that of adults. The condition can be diagnosed at a metastatic stage. Gynecological metastases of MMs often occur in the endometrium. More rarely, metastases can be detected in the ovaries. Although it is rare in adolescents, MM cases should be evaluated regarding ovarian metastases. It should be noted that adolescents can be asymptomatic no matter how large the mass is. This case report presents a case with a primary melanoma lesion in the leg and a metastatic ovarian mass detected in imaging studies performed five months after the initial diagnosis. The mass detected in the ovary in the case was removed by salphingoopherectomy. The diagnosis of metastasis was confirmed by immunohistochemical staining. Sentinel lymph node biopsy was performed concurrently with oophorectomy. Malignant melanomas may rarely metastasize gynecologically. Metastases should be considered in the differential diagnosis of adnexal mass in patients with melanoma, and the treatment plan should be arranged accordingly.

Anahtar Kelimeler

• Malignant Melanoma
• Ovary
• Adolescent
• Chemotherapy
• Sentinel

Adölesanda asemptomatik ovaryan malign melanom

Öz

Malign Melanom (MM), son derece kötü prognoza sahip bir tümördür ve adölesanlarda çok nadir görülür. Bu popülasyonda hastalığın prognozu yetişkinlerden farklıdır. Durum metastatik evrede teşhis edilebilir. MM’lerin jinekolojik metastazları sıklıkla endometriyumda meydana gelir. Daha nadiren yumurtalıklarda metastazlar saptanabilir. Adölesanlarda nadir görülmesine rağmen MM olguları over metastazları açısından değerlendirilmelidir. Unutulmamalıdır ki, kitle ne kadar büyük olursa olsun adölesanlarda asemptomatik olabilir. Bu olgu sunumunda bacakta primer melanom lezyonu ve ilk tanıdan beş ay sonra yapılan görüntüleme tetkiklerinde metastatik over kitlesi saptanan bir olgu sunulmaktadır. Olguda overde saptanan kitle salfingooferektomi ile çıkarılıp metastaz tanısı immünohistokimyasal boyama ile doğrulandı. Ooferektomi ile eş zamanlı olarak sentinel lenf nodu biyopsisi yapıldı. Malign melanomlar nadiren jinekolojik olarak metastaz yapabilirler. Melanomlu hastalarda adneksiyal kitle ayırıcı tanısında metastazlar da düşünülmeli ve tedavi planı buna göre düzenlenmelidir.

Anahtar Kelimeler

• Malign Melanom
• Yumurtalık
• Ergen
• Kemoterapi
• Sentinel

Kaynakça

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