BİLATERAL OVERYAN VE PSEUDOMYXOMA PERİTONEİ İLE BİRLİKTE YAYGIN KARIN İÇİ METASTAZLARA NEDEN OLAN APENDİKSTEN KAYNAKLANAN MÜSİNÖZ ADENOKANSER OLGUSU

Öz

Amaç: Apendiks adenokarsinomu tanısı alan, bilateral overlere ve intraabdominal kaviteye yaygın metastaz yapan, aynı zamanda pseudomyxoma peritonei saptanan bir olguyu güncel lteratür eşliğinde tartışmayı amaçladık Olgu Sunumu: İntraabdominal kitle saptanan hastaya uygulanan laparatomi sonucu yaygın karın içi metastazlar ve pseudomyxoma peritonei bulguları saptandı. İntestinal sistem eksplorasyonunda apendiks üzerinde saptanan nodüler yapılar nedeniyle apendektomi sonrası primer tümörün apendiks kökenli olduğu görüldü. Tartışma: Apendiksten kaynaklanan adenokanser olgularında yaygın karın içi ve overyan metastazlar izlenebilmektedir. Bu durum primer overyan bir maligniteyle karışabilmekte, sonuç olarak cerrahinin ve postoperatif adjuvan tedavinin şeklini etkileyebilmektedir. Bu yüzden adneksiyal kitle saptanan hastalarda dikkatli bir intestinal sistem,özellikle apendiks, incelemesi yapılmalıdır.

Anahtar Kelimeler

• Adenokanser,apendiks,pseudomyxoma peritonei

A CASE REPORT OF MUSCINOUS ADENOCANCER ORIGINATED FROM APPENDIX WHICH CAUSED BILATERAL OVARIAN AND DIFFUSE INTRAABDOMINAL METASTASIS AND PSEUDOMYXOMA PERITONEI

Öz

Objective: We would like to discuss a case diagnosed as adenocarcinoma of appendix, which has a diffuse intrabdominal metastasis and also has pseudomyxoma peritonei with the contemporary literature. Case report: As the result of the laparatomy process performed to the patient prediagnosed with intraabdominal mass lesion, diffuse metastasis and signs of pseudomyxoma peritonei. In exploration of gastrointestinal system, there has been nodular lesions determined on the appendix and therefore appendectomy has been carried out. It has been seen that the primary tumor has been originated from appendix. Discussion: In cases with adenocarcinoma of appendix, diffuse intaabdominal and ovarian metastasis can be seen. This can make a confusion about primary ovarian malignancies. As a result this issue can affect the surgical procedure and also the postoperative adjuvant treatment modalities. That is why in patients with adnexial mass lesions, particular examination of intestinal system especially appendix should be performed.

Anahtar Kelimeler

• Adenocancer,appendix,pseudomyxoma peritonei

Kaynakça

1. 1. Shimazaki J, Tabuchi T, Nishida K, Takemura A, Motohashi G, Kajiyama H, Suzuki S. Synchronous ovarian metastasis from colorectal cancer: A report of two cases. Oncol Lett, 2016, 12: 257-261.
2. 2. Shiono S, Saito T, Fujii H, Arakawa A, Nakamura T, Yao T. A case of krukenberg carcinoma metastasized from colon cancer resembling mucinous cystadenocarcinoma of yhe ovary. Int J Clin Exp Pathol, 2013, 7: 394-401.
3. 3. Vavinskaya V, Baumgartner JM, Ko A, Saenz CC, Valasek A. Low-grade appendicial mucinous neoplasm involving the endometrium and presenting with mucinous vaginal discharge. Case Reo Obstet Gynecol, 2016, 1-4.
4. 4. Carr NJ, Sobin LH. Epithelial noncarcinoid tumors and tumor like lesions of the appendiks. Cancer, 1995; 76: 2383-2384.
5. 5. Shin R, Chai YJ, Park JW, Chang MS, Bae JM, Kim MJ, Park BK, Park KJ, Jeong SY. Ultimate Clinical Outcomes of Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential. Ann Surg Oncol, 2016.
6. 6. Misdraji J, Yantiss RK, Graeme-Cook FM, Balis UJ, Young RH. Appendiceal mucinous neoplasms: a clinicopathologic analysis of 107 cases. Am J Surg Pathol.  2003  Aug; 27 (8) : 1089-103.
7. 7. Agrusa A, Romano G, Galia M, Cucinella G, Sorce V, Di Buono G, Agnello F, Amato G, Gulotta G. Appendiceal mucinous neoplasms: an uncertain nosological entity. Report of a case. G Chir. 2016 Mar-Apr;37(2):86-9.