Hamlet and Bamlet

Öz

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a compound that allows the cancer cell to die by forming a complex of oleic acid with lactoalbumin derived from human milk. BAMLET (Bovine Alpha-lactalbumin Made LEthal to Tumor cells) is a compound that causes the cancer cell to form oleic acid with lactoalbumin, which is obtained from the milk of bovine animals. Both compounds can form in the stomach as well as in vitro conditions. Tumor cells may undergo cell death in a variety of ways, including apoptosis, necrosis, and autophagic. The eff ects of both compounds on cancer cells are similar to apoptosis. Despite the fact that both animal and human studies are conducted with both compounds in the literature, they are a treatment method which is still in research stage.

Anahtar Kelimeler

• Hamlet,Bamlet,Apoptosis

Hamlet and Bamlet

Öz

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) insan sütünden elde edilen laktoalbumin ile oleik asidin kompleks oluşturarak kanser hücresinin ölmesini sağlayan bileşiktir. BAMLET (Bovine Alpha-lactalbumin Made LEthal to Tumor cells) ise büyükbaş hayvanların sütünden elde edilen laktoalbumin ile oleik asidin bileşik oluşturması ile kanser hücresine sebep olan bileşiktir. Her iki bileşik de in vitro koşullarda oluşabildiği gibi, mide de oluşabilmektedir. Tümör hücreleri apoptoz, nekroz, otofajik gibi çeşitli yollarla hücre ölümlerine uğrayabilir. Her iki bileşiğin de kanser hücreleri üzerine etkileri apoptoza benzetilmektedir. Literatürde her iki bileşikle yapılmış hayvan ve insan çalışmaları olmakla birlikte henüz araştırma aşamasında olan bir tedavi yöntemidir.

Anahtar Kelimeler

• Hamlet,Bamlet,Apoptoz

Kaynakça

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