Struma Ovarii In Our Series With Review Of The Literature And Retrospective Analysis

Öz

Objective: To evaluate clinical and pathological features of struma ovarii cases retrospectively. Materials-Metods: The present study included 8 patients reported with pathology of struma ovarii in the medical records. Archive slides were reviewed for diagnostic confirmation, regarding patterns and accompanying thyroid pathologies. Extraovarian dissemination of thyroid tissue, presence of accompanying other ovarian pathologies and that how many cases were composed of pure thyroid tissues were investigated. The clinical features were determined by screening the patient files. Data such tumor size and lateralization were obtained from the pathology reports. Results: The age of the patients ranged between 45-85 years. The most common hospital admission complaint was palpable mass. Five patients had right ovarian struma ovarii. The tumor diamater ranged between 9-15 cm. Tumor was limited by ovary in all the cases. All the struma ovarii cases demonstrated follicular pattern in the microscopic examination. No thyroid-associated malignancy was encountered. Tumor was composed of pure thyroid tissue in 6 cases. We assessed two cases as proliferative struma ovarii. Recurrence was detected during follow-ups in none of the cases. Coclusion: Struma ovarii is the most commonly seen ovarian monodermal teratoma and mostly benign. The presence of malignancy associated with thyroid should be eliminated by a careful histopathological examination in order not to hinder the chance of additional treatment.

Anahtar Kelimeler

• struma ovari
• monodermal teratoma
• germ cell tumor

Kliniğimizde Struma Ovarii Olguları: Retrospektif bir İnceleme

Öz

Amaç: Struma ovarii olgularının klinik ve patolojik özelliklerini retrospektif olarak değerlendirmek

Gereç-Yöntem: Bu çalışmaya tıbbi kayıtlarda struma ovarii tanısı olan 8 hasta dahil edildi. Arşiv preparatları tanı konfirmasyonu, izlenen paternler ve eşlik eden tiroid patolojileri için gözden geçirildi. Tiroid dokusunun over dışı yayılımı, eşlik eden diğer over patolojilerinin varlığı ve kaç tümörün saf tiroid dokusundan oluştuğu araştırıldı. Klinik özellikler hasta dosyaları taranarak belirlendi. Tümör boyutu ve lateralizasyon gibi veriler patoloji raporlarından elde edildi.

Bulgular: Hastaların yaşı 45-85 arasında değişmekteydi. En sık hastaneye başvuru şikayeti ele gelen kitleydi. Beş hastada sağ overde struma ovarii saptadık. Tümör çapları 9-15 cm arasında değişmekteydi. Tüm olgularda tümör overler ile sınırlıydı. Tüm struma ovarii olguları mikroskobik incelemede foliküler patern gösterdi. Altı olguda tümör sadece tiroid dokusundan oluşuyordu. Tiroidle ilişkili malignite ile karşılaşılmadı. İki olguyu proliferatif struma ovarii olarak değerlendirdik. Hiçbir olguda takiplerde nüks saptanmadı.

Sonuç: Struma ovarii en sık görülen overyan monodermal teratomudur ve çoğunlukla benigndir. Tiroid ile ilişkili malignite varlığı, ek tedavi şansını engellememek için dikkatli bir histopatolojik inceleme ile ekarte edilmelidir. 

Anahtar Kelimeler

• struma ovarii
• monodermal teratoma
• germ cell tumor

Kaynakça

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