Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective

Serkan Karaçetin; Meryem Akpolat Ferah; Mete Keçeci

TR EN

Hiperglisemik Gebeliklere Bağlı Fetal Değişiklikler - Deneysel Perspektif

Öz

Gebelikte hiperglisemi, fetal komplikasyonlarla ilişkili diyabetik bir durum meydana getirir. Veriler incelendiğinde gebelerde diabetes mellitus oranı ile paralel artan fetal kayıplar ve olumsuz değişiklikler göze çarpmaktadır. Gebe kalma yaşının ilerlemesi ve her geçen gün uygun olmayan yaşam koşullarının artması ile hiperglisemik gebelikler ve buna bağlı olumsuz fetal değişiklikler artmakta ve neticede gelecek nesilleri etkileyecek global bir sağlık riski ortaya çıkmaktadır. Uluslararası Diyabet Federasyonu’nun sunduğu verilere göre, yaklaşık 21 milyon gebelik hiperglisemiden etkilenmektedir. Özellikle son yıllarda yapılan çok sayıda güncel çalışma, diyabetin meydana getirdiği hasarların dişi üreme sistemi ve fetal sağlık sorunları ile yakın ilişkide olduğunu göstermiş ve dolayısıyla hiperglisemik gebeliklerin önemini gözler önüne sermiştir. Bu derlemedeki amaç gebelik öncesinde ve gebelikte deneysel modellerle oluşturulmuş diyabetin, gebelik sürecinde fetüs üzerinde yapmış olduğu değişiklikler hakkında genel ve karşılaştırmalı bir bakış açısı sağlamaktır.

Anahtar Kelimeler

Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective

Öz

Hyperglycemia during pregnancy induces a diabetic condition associated with fetal complications. Examination of the data reveals that fetal losses and adverse fetal outcomes increase in parallel with the prevalence of diabetes mellitus among pregnant women. Advancing maternal age and the progressive deterioration of living conditions contribute to a rise in hyperglycemic pregnancies and associated adverse fetal changes, ultimately posing a global health risk that may affect future generations. According to data provided by the International Diabetes Federation, approximately 21 million pregnancies are affected by hyperglycemia during gestation. In recent years, numerous contemporary studies have demonstrated that the damage caused by diabetes is closely linked to female reproductive system dysfunctions and fetal health issues, thereby highlighting the significance of hyperglycemic pregnancies. The aim of this review is to provide a general and comparative perspective on the changes induced in the fetus by diabetes, experimentally modeled before and during pregnancy, throughout the gestational period

Anahtar Kelimeler

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Endokrinoloji

Bölüm

Derleme

Yazarlar

Serkan Karaçetin ^*
0000-0002-8670-4812
Türkiye

Meryem Akpolat Ferah
0000-0002-3419-1728
Türkiye

Mete Keçeci
0000-0002-2144-4730
Türkiye

Yayımlanma Tarihi

30 Nisan 2026

Gönderilme Tarihi

19 Kasım 2025

Kabul Tarihi

18 Nisan 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 10 Sayı: 1

IZ

https://izlik.org/JA65UJ33TX

Kaynak Göster

RIS / Bibtex

APA

Karaçetin, S., Akpolat Ferah, M., & Keçeci, M. (2026). Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective. Turkish Journal of Diabetes and Obesity, 10(1), 94-106. https://izlik.org/JA65UJ33TX

AMA

1.Karaçetin S, Akpolat Ferah M, Keçeci M. Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective. Turk J Diab Obes. 2026;10(1):94-106. https://izlik.org/JA65UJ33TX

Chicago

Karaçetin, Serkan, Meryem Akpolat Ferah, ve Mete Keçeci. 2026. “Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective”. Turkish Journal of Diabetes and Obesity 10 (1): 94-106. https://izlik.org/JA65UJ33TX.

EndNote

Karaçetin S, Akpolat Ferah M, Keçeci M (01 Nisan 2026) Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective. Turkish Journal of Diabetes and Obesity 10 1 94–106.

IEEE

[1]S. Karaçetin, M. Akpolat Ferah, ve M. Keçeci, “Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective”, Turk J Diab Obes, c. 10, sy 1, ss. 94–106, Nis. 2026, [çevrimiçi]. Erişim adresi: https://izlik.org/JA65UJ33TX

ISNAD

Karaçetin, Serkan - Akpolat Ferah, Meryem - Keçeci, Mete. “Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective”. Turkish Journal of Diabetes and Obesity 10/1 (01 Nisan 2026): 94-106. https://izlik.org/JA65UJ33TX.

JAMA

1.Karaçetin S, Akpolat Ferah M, Keçeci M. Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective. Turk J Diab Obes. 2026;10:94–106.

MLA

Karaçetin, Serkan, vd. “Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective”. Turkish Journal of Diabetes and Obesity, c. 10, sy 1, Nisan 2026, ss. 94-106, https://izlik.org/JA65UJ33TX.

Vancouver

1.Serkan Karaçetin, Meryem Akpolat Ferah, Mete Keçeci. Fetal Changes Associated with Hyperglycemic Pregnancies – An Experimental Perspective. Turk J Diab Obes [Internet]. 01 Nisan 2026;10(1):94-106. Erişim adresi: https://izlik.org/JA65UJ33TX