COVID-19 Pandemisi ve Diabetes Mellitus

Öz

Coronavirüs ailesinden SARS-CoV-2’nin neden olduğu COVID-19 pandemisi, ilk olarak Çin’de görülen ve bulaşıcılık özelliği yüksek bir hastalıktır. Hastalığın mortalite ve morbiditesinde diyabet başta olmak üzere komorbid hastalıkların varlığı ve ileri yaş belirleyici olmaktadır. COVID-19 tarafından tetiklenen hücresel mekanizmalar ve diyabet patofizyolojisi, diyabetli bireyleri potansiyel organ hasarı ile sonuçlanacak bir sitokin fırtınasına daha duyarlı hale getirmektedir. COVID-19 ile infekte olmuş diyabetik hastalarda hastaneye başvuru, yatış oranları, şiddetli pnömoni gelişimi ve diğer komorbit hastalıklara göre daha yüksek mortalite oranlarının olduğu gösterilmiştir. Bu risk, iyi glisemik kontrol ile tamamen ortadan kaldırılmasa da azaltılabilmektedir. Diyabetli hastalarda hem glisemik regülasyon hem de eşlik eden kalp hastalığı, hipertansiyon, obezite veya böbrek hastalığı gibi komorbid durumların stabilizasyonu sağlanmalıdır.

Anahtar Kelimeler

• Pandemi
• Coronavirus
• SARS-CoV-2
• COVID-19
• Diabetes mellitus

Öz

The COVID-19 pandemic, caused by SARS-CoV-2 of Coronaviruses types, is a highly infectious disease caused by SARS-CoV-2, which first appeared in China. The presence of comorbid diseases, especially diabetes, and advanced age are determinant for the mortality and morbidity of the disease. Considering the cellular mechanisms triggered by COVID-19 and the pathophysiology of diabetes, make individuals with diabetes more susceptible to a cytokine storm with potential organ damage. Studies have reported that individuals with diabetes and who have been infected by COVID-19 showed higher admission rates to hospitals, development of severe pneumonia as well as higher mortality rates, when compared to those without comorbidities. This risk can be reduced, though not completely eliminated, by good glycemic control. In patients with diabetes, both glycemic regulation and stabilization of comorbid conditions such as concomitant heart disease, hypertension, obesity or kidney disease should be provided. Key Words: Pandemic, Coronavirus, SARS-CoV-2, COVID-19, Diabetes mellitus

Anahtar Kelimeler

• Diabetes mellitus
• COVID-19
• SARS-CoV-2
• Coronavirus
• Pandemic

Kaynakça

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