Chronıc Exposure to Pestıcıdes and Parkınson Dısease

Yıl 2017, Sayı: Issue 1(2) - 3. INTERNATIONAL BIOCIDAL CONGRESS, 33 - 33, 01.02.2017

Maide Nur Kartal Yıldız Pekşen Elif Nur Köksal

Öz

Aim and
material, Methods: While the prevalence of Parkinson’s disease differs between
80,6 and 187 out of hundred thousand in the world, this prevalence has been
reported as 111 out of hundred thousand in our country. The purpose of this
review, which has been conducted by examining national and international
literature, is to attract attention to pesticide exposure which one is of the
preventable risk factors of this disease the prevalence of which is thought to
increase in our aging society. Results: Studies conducted in literature
emphasize the association between pesticide exposure and psychiatric and neurological
diseases such as depression, Alzheimer’s disease, Parkinson’s disease and ALS.
In some studies, the risk of developing Parkinson’s disease has been found high
in individuals who carry GSTP-1 genotype of glutathione which ensures the
metabolization of pesticides. In a study conducted in England, pesticides that
contain especially rotenon and paraquat have been found to be associated with
Parkinson’s disease. Experiments conducted with animals and cell culture
studies have also shown that pesticide exposure causes neurodegenerative
changes that cause the development of Parkinson’s disease. When compared with
European Union countries, the amount of pesticide per hectare in our country is
far more behind these countries. However, in Mediterranean, Aegean and Marmara
regions where agriculture is carried out intensively, pesticide use has
approached the level of developed countries. Thus, pesticide residues on food
come out as a factor that threatens public health. Conclusion: Studies
conducted show that chronic pesticide exposure can cause Parkinson’s disease
with neurodegenerative processes. In line with the data obtained, it has been
concluded that primary and secondary protection measures should be conducted to
minimize the exposure of both agriculture workers as those who apply pesticide
and consumers who will be exposed to pesticide residues.

 

 

 

 

Keywords:
pesticide,
Parkinson’s disease, biocidal products

Anahtar Kelimeler

Chronıc Exposure to Pestıcıdes and Parkınson Dısease

Kaynakça

• Maide Nur Kartal, Yıldız Pekşen, Elif Nur Köksal Ondokuz Mayıs Unıversty Departments Of Public Health, Samsun Public Health Administration, Giresun