Impact of Smoking on Respiratory Function in Young Women

Yıl 2025, Cilt: 11 Sayı: 4, 349 - 355, 31.12.2025

Muhammed Fatih Bilici , Murat Çelik

https://doi.org/10.18826/useeabd.1768180

Öz

Aim: The aim of this study was to examine the effects of cigarette smoking on selected respiratory functions in young women.
Method: A total of 40 young women voluntarily participated in the study. Participants were divided into non-smoker (n = 20; age: 19.8 ± 1.54 years, height: 163.05 ± 6.64 cm, body weight: 55.6 ± 6.79 kg) and smoker groups (n = 20; age: 20.2 ± 1.82 years, height: 163.5 ± 4.59 cm, body weight: 55.4 ± 11.45 kg). All participants were apparently healthy and reported engaging in regular light-to-moderate physical activity as part of their daily routines; however, none were involved in organized or competitive sports training programs. The smoker group consisted of individuals who reported daily cigarette smoking for at least three consecutive years, while the non-smoker group included participants with no history of smoking or substance dependence. Respiratory function parameters were assessed using a spirometer under standardized conditions. Statistical analysis was performed using SPSS software. Data normality was evaluated using the Shapiro–Wilk test, and since the data were not normally distributed, group comparisons were conducted using the Mann–Whitney U test. The level of statistical significance was set at α = 0.05.
Results: Statistically significant differences were observed in all measured respiratory parameters-including forced vital capacity (FVC), forced expiratory volume in one second (FEV₁), FEV₁/FVC ratio, peak expiratory flow (PEF), forced expiratory flow at 25-75% of vital capacity (FEF₂₅-₇₅), vital capacity (VC), and maximal voluntary ventilation (MVV)-with consistently higher values recorded in the non-smoker group (p<0.05).
Conclusion: The findings demonstrate that cigarette smoking is associated with a pronounced negative impact on pulmonary function in young women, resulting in significant reductions across multiple spirometric parameters even in the absence of structured sports training.

Anahtar Kelimeler

Addiction , Respiration , Smoking , Women

Yetişkin Kadınlarda Sigaranın Solunum Fonksiyonu Üzerindeki Etkisi

Öz

Amaç: Bu çalışmanın amacı, sigara kullanımının genç kadınlarda seçilmiş solunumsal fonksiyonlar üzerindeki etkilerini incelemektir.
Yöntem: Çalışmaya toplam 40 genç kadın gönüllü olarak katılmıştır. Katılımcılar, sigara içmeyen (n = 20; yaş: 19,8 ± 1,54 yıl; boy: 163,05 ± 6,64 cm; vücut ağırlığı: 55,6 ± 6,79 kg) ve sigara içen (n = 20; yaş: 20,2 ± 1,82 yıl; boy: 163,5 ± 4,59 cm; vücut ağırlığı: 55,4 ± 11,45 kg) gruplarına ayrılmıştır. Tüm katılımcılar görünür biçimde sağlıklı olup günlük rutinleri kapsamında hafif-orta düzeyde fiziksel etkinlikte bulunduklarını bildirmiş, ancak hiçbiri düzenli veya rekabetçi spor antrenman programlarına dahil olmamıştır. Sigara içen grup, en az üç yıl boyunca her gün sigara içtiğini bildiren bireylerden; sigara içmeyen grup ise sigara veya madde kullanım öyküsü bulunmayan kişilerden oluşmuştur. Solunum fonksiyonu parametreleri standardize koşullar altında bir spirometre kullanılarak değerlendirilmiştir. İstatistiksel analiz SPSS yazılımı ile gerçekleştirilmiştir. Veri dağılımının normalliği Shapiro–Wilk testi ile incelenmiş; verilerin normal dağılmaması nedeniyle grup karşılaştırmalarında Mann–Whitney U testi kullanılmıştır. İstatistiksel anlamlılık düzeyi α = 0,05 olarak belirlenmiştir.
Bulgular: Zorunlu vital kapasite (FVC), bir saniyedeki zorlu ekspiratuvar hacim (FEV₁), FEV₁/FVC oranı, tepe ekspiratuvar akım (PEF), vital kapasitenin %25–75’lik aralığında zorlu ekspiratuvar akım (FEF₂₅–₇₅), vital kapasite (VC) ve maksimal istemli ventilasyon (MVV) dâhil olmak üzere tüm solunumsal parametrelerde istatistiksel olarak anlamlı farklılıklar gözlenmiş; sigara içmeyen grupta sistematik biçimde daha yüksek değerler kaydedilmiştir (p < 0,05).
Sonuç: Bulgular, sigara kullanımının genç kadınlarda akciğer fonksiyonları üzerinde belirgin ve olumsuz bir etkiye sahip olduğunu, düzenli spor antrenmanı olmaksızın dahi birçok spirometrik parametrede anlamlı düşüşlere yol açtığını göstermektedir.

Anahtar Kelimeler

Solunum , Sigara , Kadın , Bağımlılık

Kaynakça

• Abdelaal, A. A. M., & Mousa, G. S. M. (2022). Impact of cigarettes smoking on undergraduates’ lung health and functional performance: observational cross-sectional study. International Journal of Preventive Medicine, 13(1), 59.
• Alobaidi, N. Y., Almeshari, M., Stockley, J., Stockley, R. A., & Sapey, E. (2022). Small airway function measured using forced expiratory flow between 25% and 75% of vital capacity and its relationship to airflow limitation in symptomatic ever-smokers: a cross-sectional study. BMJ Open Respiratory Research, 9(1), e001385.
• American Cancer Society. (2024, November 19). Harmful chemicals in tobacco products. https://www.cancer.org
• Bilici, M. F., & Genç, A. (2020). The effects of smoking addiction and physical activity on some respiratory functions in female university students. Pedagogy of Physical Culture and Sports (Pedagogy), 24(2), 54-58. https://doi.org/10.15561/26649837.2020.0201
• Centers for Disease Control and Prevention. (2024, September 17). Health effects of cigarettes: Cancer. https://www.cdc.gov
• Chung, C., Lee, K. N., Han, K., Shin, D. W., & Lee, S. W. (2023). Effect of smoking on the development of chronic obstructive pulmonary disease in young individuals: a nationwide cohort study. Frontiers in Medicine, 10, 1190885.
• Çolak, Y., Nordestgaard, B.G., Lange, P., & Afzal, S. (2025). Sex differences in COPD in relation to smoking exposure: A population-based cohort study. Thorax, 80(8), 512-519. https://doi.org/10.1136/thorax-2024-222682.
• Flor, L. S., Anderson, J. A., Ahmad, N., Aravkin, A., Carr, S., Dai, X., ... & Gakidou, E. (2024). Health effects associated with exposure to secondhand smoke: A burden of proof study. Nature medicine, 30(1), 149-167. https://doi.org/10.1038/s41591-023-02743-4
• Herath, P., Wimalasekera, S. W., Amarasekara, T. D., Fernando, M. S., & Turale, S. (2025). Comparison of respiratory symptoms and pulmonary functions of adult male cigarette smokers and non-smokers in Sri Lanka; A comparative analytical study. PloS one, 20(2), e0315095.
• Juneau, D., Leblond, A., Chatta, R., Lévesque, V., Lussier, A., & Dubé, B. P. (2024). SPECT/CT to quantify early small airway disease and its relationship to clinical symptoms in smokers with normal lung function: A pilot study. Frontiers in physiology, 15, 1417463. https://doi.org/10.3389/fphys.2024.1417463
• Juneau, D., Porres-Aguilar, M., & Albuja-Cruz, M. (2024). SPECT/CT to quantify early small airway disease and its clinical applications. Frontiers in Physiology. https://doi.org/10.3389/fphys.2024.1368452
• Li, T., Zhou, H. P., Zhou, Z. J., Guo, L. Q., & Zhou, L. (2021). Computed tomography-identified phenotypes of small airway obstructions in chronic obstructive pulmonary disease. Chinese Medical Journal, 134(17), 2025-2036.
• Mehta, B.M., & Satani, K. (2022). Study of peak expiratory flow rate in young smokers in community. International Journal of Community Medicine and Public Health, 9(2), 872-876.
• Miller, M. R., Hankinson, J., Brusasco, V., Burgos, F., Casaburi, R., Coates, A., … Wanger, J. (2005). Standardisation of Spirometry. European Respiratory Journal, 26(2), 319-338. https://doi.org/10.1183/09031936.05.00034805
• Nair, G., Xing, Y. J., Luong, A., Bashar, F., Nowacki, A., Stevens, C., ... & Castillo, E. (2025). CT-derived functional imaging biomarkers combined with FEV1 for predicting 10-year all-cause mortality in COPDGene cohort. npj Biomedical Innovations, 2(1), 25.
• Oelsner, E. C., Balte, P. P., Bhatt, S. P., Cassano, P. A., Couper, D., Folsom, A. R., ... Yende, S. (2020). Lung function decline in former smokers and low-intensity current smokers: A secondary data analysis of the NHLBI Pooled Cohorts Study. The Lancet Respiratory Medicine, 8(1), 34-44.
• Pallant, J. (2020). SPSS survival manual: A step-by-step guide to data analysis using IBM SPSS (7th ed.). London, UK: Routledge. https://doi.org/10.4324/9781003117452
• Pavić, I., Topalušić, I., Poljičanin, T., Hofmann Jaeger, O., Žaja, S., & Stipić Marković, A. (2024). Secondhand Smoke Exposure and Its Impact on Pediatric Lung Function, Aerobic Fitness, and Body Mass: Evidence from a Cross-Sectional Study. Children, 11(10), 1250. https://doi.org/10.3390/children11101250
• GBD 2019 Tobacco Collaborators (2021). Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: A systematic analysis from the Global Burden of Disease Study 2019. Lancet (London, England), 397(10292), 2337.
• Ritchie, A. I., Donaldson, G. C., Hoffman, E. A., Allinson, J. P., Bloom, C. I., Bolton, C. E., ... & Wedzicha, J. A. (2024). Structural predictors of lung function decline in young smokers with normal spirometry. American Journal of Respiratory and Critical Care Medicine, 209(10), 1208-1218.
• Sharma, A. K., Sorte, S. R., Rathod, S. B., & Phatak, M. (2024). Early respiratory mechanics alterations in smokers: Correlative analysis of the forced oscillation technique and computerized spirometry. Cureus. 16(12), e76677.
• Tian, T., Jiang, X., Qin, R., Ding, Y., Yu, C., Xu, X., & Song, C. (2023). Effect of smoking on lung function decline in a retrospective study of a health examination population in Chinese males. Frontiers in Medicine, 9, 843162.
• Trakas, N., Georgakopoulou, V. E., Melemeni, D., Damaskos, C., Mantzouranis, K., Garmpis, N., ... & Tsiafaki, X. (2022). Association between smoking cessation and alterations in forced expiratory volume in one second (FEV1). A Follow-Up Study from a Greek Tobacco Cessation Clinic. Addiction & Health, 14(2), 87-95.
• U.S. Food and Drug Administration (2020, May 1). Chemicals in tobacco products and your health. https://www.fda.gov
• Weber, P., Menezes, A. M. B., Gonçalves, H., de Oliveira, P. D., Wendt, A., Perez-Padilla, R., & Wehrmeister, F. C. (2024). Smoking exposure trajectories and pulmonary function in early adulthood in a Brazilian cohort. Pulmonology, 31(1). https://doi.org/10.1016/j.pulmoe.2023.09.005
• World Health Organization. (2024, January 16). Tobacco use declines despite tobacco industry efforts to jeopardize progress. WHO. https://www.who.int/news/item/16-01-2024-tobacco-use-declines-despite-tobacco-industry-efforts-to-jeopardize-progress
• Zhou, Y., Wu, F., Deng, Z., Wang, Z., Tian, H., Huang, P., ... & Ran, P. (2025). Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: A 15-year prospective cohort study in China. Respiratory Research, 26(1), 169.