Kekik Bitkisinin Kanatlı Hayvan Beslemede Alternatif Yem Katkısı Olarak Kullanım Olanakları

Yıl 2025, Cilt: 9 Sayı: 2, 125 - 143, 30.12.2025

Ali Doğan , Metin Duru

https://doi.org/10.47137/usufedbid.1741190

https://izlik.org/JA27LC34TC

Öz

Hayvansal kaynaklı protein insanların sağlıklı ve güvenli beslenmesinde elzem olduğu, bu protein kaynağının karşılanmasında ise kanatlı sektörü önemli bir yer tuttuğu bilinen bir gerçektir. Hayvan beslemede toplam giderlerin %55-70’ini yem giderleri oluşturmakta, bu giderlerin minimize edilebilmesi için alternatif yem katkılarının kullanımına yönelik yapılan çalışmalar günümüzde giderek artmaktadır. Fitojenik bitkiler yem katkısı olarak içerisinde bulunan biyoaktif katkı maddelerinin hayvan verimini ve sağlığını olumlu yönde etkilemesi sebebi ile çalışmalar devam etmekte ve halihazırda kullanılmaktadır. Ülkemizin en önemli yabani ürünü kekik olup, dünyanın en fazla kekik üreticisi Ülkemizdir. İçeriğinde mevcut olan uçucu yağ ve diğer etken maddeler sebebi ile çok uzun yıllardır eczacılık ve tıp alanında yaygın olarak kullanılan kekik, hayvan besleme alanında da uzun yıllardır kullanılmaktadır. Bu derlemede kekiğin kanatlı hayvan beslemede kullanımına yönelik yürütülen çalışmalar değerlendirilmiştir.

Anahtar Kelimeler

Kanatlı hayvan , Kekik , alternatif yem katkısı , fitojenik yem katkısı

Possibilities of Using Thyme Plant as Alternative Feed Additive in Poultry Feeding

https://izlik.org/JA27LC34TC

Öz

It is a known fact that protein of animal origin is essential for healthy and safe nutrition of humans, and the poultry sector has an important place in meeting this protein source. Feed expenses constitute 55-70% of total expenses in animal nutrition, and studies on the use of alternative feed additives in order to minimize these expenses are increasing day by day. Phytogenic plants are currently being used as feed additives due to the positive effect of bioactive additives on animal productivity and health. The most important wild product of our country is thyme and our country is the world's largest producer of thyme. Thyme, which has been widely used in pharmacy and medicine for many years due to its essential oil and other active ingredients, has also been used in animal nutrition for many years. In this review, studies on the use of thyme in poultry nutrition were evaluated.

Anahtar Kelimeler

Poultry , Thyme , alternative feed additive , phytogenic feed additive

Kaynakça

• Duru M and Arslan Duru A. Anasonun (Pimpinella anisum) yem katkı maddesi olarak kanatlı hayvan beslemede kullanımı. Contemporary Approaches in Health Sciences, Hatipoğlu Fatih (Editör), All Sciences Academy, Konya, 2024, s: 176-190.
• Barıt M and Arslan Duru A. The effects of goji berry (Lycium barbarum L.) leaves on performance, meat lipid oxidation, digestive tract parts, and some blood parameters of broiler chickens. Journal of the Hellenic Veterinary Medical Society, 2023; 74(2): 5687-5696.
• Meral R, Doğan İS and Kanberoğlu GS. Fonksiyonel gıda bileşeni olarak antioksidanlar. Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2012; 2(2), 45-50.
• Gür EN. Tarladan sofraya uzanan bir zincir: gıda güvenliği; 2020 [cited 2024]. Erişim: https://www.yesilay.org.tr/tr/makaleler/tarladan-sofraya-uzanan-bir-zincir-gida-guvenligi.
• Kara O. Fonksiyonel Gıda Üretiminde Yeni Yaklaşımlar. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2024; 29(3): 1064-1081.
• Vignesh A, Amal TC, Sarvalingam A and Vasanth K. A review on the influence of nutraceuticals and functional foods on health. Food Chemistry Advances, 2024; 5: 100749. https://doi.org/10.1016/j.focha.2024.100749.
• Castanon JIR. History of the use of antibiotic as growth promoters in european poultry feeds. Poultry Science, 2007; 86(11), 2466-2471. https://doi.org /10.3382/ps.2007-00249.
• Tuncer Hİ. Karma yemlerde kullanımı yasaklanan hormon, antibiyotik, antikoksidiyal ve ilaçlar. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi, 2007; 47(1), 29-37.
• Sevim, B. and Cufadar, Y. Effects of an addition of different essential oils and their combinations to diets on performance and carcass characteristics parameters in broilers. Turkish Journal of Agriculture-Food Science and Technology, 2017; 5(8): 964-968. https://doi.org/10.24925/turjaf.v5i8.964-968.1261.
• Küçükkurt İ ve Fidan AF, Saponinler ve bazı biyolojik etkileri. Kocatepe Veteriner Dergisi, 2008; 1, 89-96.
• Gürsoy E. Bitkisel ekstraktların hayvan beslemede kullanımı. Kadirli Uygulamalı Bilimler Fakültesi Dergisi, 2021; 1(1), 71-79.
• Duru M. Demir dikeni (Tribulus terrestris) saponin ekstraktının yumurtacı tavuklarda performans, yumurta kalite kriterleri ve bazı kan parametreleri üzerine etkileri. Türk Tarım – Gıda Bilim ve Teknoloji Dergisi, 2024; 12(3): 423-429. https://doi.org/10.24925/turjaf.v12i3.423-429.6684.
• Kamel C. Natural plant extracts: Classical remedies bring modern animal production solutions. (Brufau). Feed manufacturing in the mediterranean region. Improving safety: from feed to food. Baskı yeri: Zaragoza. Ciheam-Iamz Press, No. 54; 2001.
• Güler T, Dalkılıç B, Çiftçi M, Ertaş ON, Dikici A, Özdemir P and Bozkurt ÖP. Broyler rasyonuna katılan kekik ve anason yağları ile antibiyotiğin toplam sekal koliform bakteri sayısı üzerine etkisi. Doğu Anadolu Bölgesi Araştırmaları, 2005a; 47-52.
• Güler T and Dalkılıç B. Aromatik bitkilerin organik (ekolojik) hayvancılıkta kullanım imkanı (Derleme), Doğu Anadolu Bölgesi Araştırma ve Uygulama Merkezi (DAUM), 2005b; 3(2): 13-20.
• Tipu MA, Akhtar MS, Anjum MI and Raja ML. New dimension of medicinal plants as animal feed. Pakistan Veterinary Journal, 2006; 26(3): 144-148.
• Özhatay N, Byfıeld A ve Atay S. Türkiye’nin 122 önemli bitki alanı, WWF Türkiye, İstanbul, 2008.
• Başer KHC. Tıbbi ve aromatik yabani bitkilerimiz tehdit altında mı? TEMA Vakfı Faaliyet Dergisi, 1998; 44-47.
• Tan A. Türkiye bitki genetik kaynakları ve muhafazası. Anadolu Ege Tarımsal Araştırma Enstitüsü Dergisi, 2010; 20(1): 7-25.
• Başer KHC. Tıbbi ve aromatik bitkilerin ilaç ve alkollü içki sanayilerinde kullanımı. İstanbul Ticaret Odası, 1997; Yayın No: 1997–39, İstanbul.
• Özhatay N, Koyuncu M, Atay S and Byfield A. Türkiye'nin Doğal Tıbbi Bitkilerinin Ticareti Hakkında Bir Çalışma. Wwfuk/Stanley Smith Horticultural Trust. Doğal Hayatı Koruma Derneği, 1997; İstanbul, Türkiye ISBN 975-96081-9-7.
• Kutlu HR. Büyüme uyarıcı antibiyotiklere karşı seçenek aranıyor. Cumhuriyet / Tarım, 13.02.2007, Sayfa:19.
• Baser KHC. The Turkish Origanum species in Oregano, The general Origanum and Lippia. Edited by Spiridon E. Kintzios, Taylor and Francis Group, LLC, London and Newyork, 2002.
• Başer KHC. Kekik. Tabiat ve İnsan, 2022; 1(191), 15-31.
• Baser KHC, Özek T, Kürkçüoglu M and Tümen G. The essential oil of Origanum vulgare subsp. hirtum of Turkish origin. Journal of Essential Oil Research, 1994; 6: 31-36.
• Saraç HG. Kekik (Origanum onites) uçucu yağının etlik piliç rasyonlarında besi performansı, jejenal villus uzunluğu ve bazı kan parametreleri üzerine etkisi. T.C. Atatürk Üniversitesi Sağlık Bilimleri Enstitüsü Hayvan Besleme ve Beslenme Hastalıkları Anabilim Dalı, Doktora Tezi, 2019; 101 s.
• Kutlular Ö. Bazı adaçayı ve kekik türlerinin uçucu yağlarının süper ısıtılmış su ile ekstraksiyonları ve Gc-Ms ile karakterizasyonları. Pamukkale Üniversitesi Fen Bilimleri Enstitüsü Yüksek Lisans Tezi, 2007; 83 s.
• Kılıçgün H and Korkmaz M. Hepatoprotective and antidiabetic activity of Origanum minutiflorum grown wild in Turkey. Bothalia Journal, 2014; 44(3): 260-267.
• Khorsand GJ, Morshedloo MR, Mumivand H, Bistgani ZE, Maggi F and Khademi A. Natural diversity in phenolic components and antioxidant properties of oregano (Origanum vulgare L.) accessions, grown under the same conditions. Scientific Reports, 2022;12: 5813. https://doi.org/10.1038/s41598-022-09742-4.
• Vazirian M, Mohammadi M, Farzaei MH, Amin G and Amanzadeh Y. Chemical composition and antioxidant activity of Origanum vulgare subsp. vulgare essential oil from Iran. Directory of Open Access Journals, 2015; 2:41–46.
• Russo M, Galletti GC, Bocchini P and Carnacini A. Essential oil chemical composition of wild populations of Italian oregano spice Origanum vulgare ssp. Hirtum (Link) Ietswaart): A preliminary evaluation of their use in chemotaxonomy by cluster analysis. 1. inflorescences. Journal of Agricultural and Food Chemistry, 1998; 46:3741–3746. https://doi.org/10.1021/jf980087w.
• Ilic Z, Stanojevic L, Milenkovic L, Sunic L, Milenkovic A, Stanojevic J and Cvetkovic D. The yield, chemical composition, and antioxidant activities of essential oils from different plant parts of the wild and cultivated oregano (Origanum vulgare L.). Horticulture, 2022; 8:1042. https://doi.org/10.3390/horticulturae8111042.
• Oniga I, Puscas C, Silaghi-Dumitrescu R, Olah NK, Sevastre B, Marica R, Marcus I, Sevastre-Berghian A, Benedec D and Pop C. Origanum vulgare ssp. vulgare: Chemical composition and biological studies. Molecules, 2018; 23:2077. https://doi.org/10.3390/molecules23082077.
• Kolypetri S, Kostoglou D, Nikolaou A, Kourkoutas Y and Giaouris E. Chemical composition, antibacterial and antibiofilm actions of oregano (Origanum vulgare subsp. Hirtum) essential oil against Salmonella typhimurium and Listeria monocytogenes. Foods, 2023; 12:2893. https://doi.org/10.3390/foods12152893.
• Khan M, Khan ST, Khan NA, Mahmood A, Al-Kedhairy AA and Alkhathlan HZ. The composition of the essential oil and aqueous distillate of Origanum vulgare L. growing in saudi arabia and evaluation of their antibacterial activity. Arabian Journal of Chemistry, 2018; 11: 1189–1200. https://doi.org/10.1016/j.arabjc.2018.02.008.
• Hao Y, Li J and Shi L. A carvacrol-rich essential oil extracted from oregano (Origanum vulgare “hot & spicy”) exerts potent antibacterial effects against Staphylococcus aureus. Frontiers in Microbiology, 2021; 12:741861.
• Baj T, Biernasiuk A, Wróbel R and Malm A. Chemical composition and in vitro activity of Origanum vulgare L., Satureja hortensis L., Thymus serpyllum L. and Thymus vulgaris L. essential oils towards oral isolates of candida albicans and candida glabrata. Open Chemistry. 2020; 18:108–118. https://doi.org/10.1515/chem-2020-0011.
• Valdez G, Shyur LF, Wang SY and Chen SE. Phytogenics in ginger, Origanum vulgare, and Syzygium aromaticum and their potential as a feed additive against Clostridium perfringens in broiler production. Animals 2023; 13:3643. https://doi.org/10.3390/ ani13233643.
• TUİK. Türkiye İstatistik Kurumu. Bitkisel Üretim İstatistikleri (Baharat Bitkileri); 2025 [alıntı 2025 Haziran 29]. Erişim: https://data.tuik.gov.tr/Kategori/GetKategori?p=tarim-111.
• Anonim. Kekik (Origanum onites, Origanum vulgare, Thymus vulgaris) Tarımı ve Endüstrisi (Fizibilite Raporu). Batı Akdeniz Kalkınma Ajansı, 2021; 61 s.
• Jamroz D and Kamel C. Plant extracts enhance broiler performance. Journal of Animal Science, 2002; 80(1): 41.
• Demir E, Sarıca Ş, Özcan MA and Sui Mez M. The use of natural feed additives as alternatives for an antibiotic growth promoter in broiler diets. British Poultry Science, 2003; 44:44-45. https://doi.org/10.1080/713655288.
• Hernandez F, Madrid J, Garcia V, Orengo J and Megias MD. Influence of two plant extracts on broilers performance, digestibility, and digestive organ size. Poultry Science, 2004; 83:169-174.
• Avcı S. Etlik piliç karma yemlerinde bitkisel ekstrakt kullanımının besi performansına etkileri. Çukurova Üniversitesi Fen Bilimleri Enstitüsü Zootekni Anabilim Dalı, Yüksek Lisans Tezi, 2004; 56 s.
• Alçiçek A, Bozkurt M and Çabuk M. The effect of a mixture of herbal essential oils, an organic acid or a probiotic on broiler performance. South African Journal of Animal Science, 2004; 34: 217-222.
• Saini R, Davis S and Dudley-Cash, W. Oregano Essential Oil Recudes Necrotic enteritis in Broilers. XXII World’s Poultry Congress (Book of Abstracts), June 8-13, 2004; 582.
• Greathead H and Kamel C. Encapsulated plant extracts to fight coccidiosis. Feed Mix, 2006; 14: 18-21.
• Basmacıoğlu H, Tokuşoğlu Ö and Ergül M. The effect of oregano and rosemary essential oils or alpHa-tocopHeryl acetate on performance and lipid oxidation of meat enriched with n-3 PUFA’s in broilers. South African Journal of Animal Science, 2004; 34: 197-210.
• Dalkılıç B, Güler T, Ertaş ON ve Çiftçi M. Broyler rasyonlarına katılan kekik ve anason yağları ile antibiyotiğin toplam sekal koliform bakteri sayısı üzerine etkisi. 3. Ulusal Hayvan Besleme Kongresi, 7-10 Eylül, 2005; 378-382.
• Erener G, Ocak N, Ak FB ve Altop A. Nane (mentol) ve Kekik (karvakrol) esans yağı ilave edilen karmalar ile yemlenen etlik piliçlerin performansları. 3. Ulusal Hayvan Besleme Kongresi, Adana. 7-10 Eylül, 2005; 58-62.
• Ertaş ON, Güler T, Çiftçi M, Dalkılıç B and Şimsek ÜG. The effect of an essential oil mix derived from oregano, clove and anise on broiler performance. International Journal of Poultry Science, 2005; 4(11): 879-884.
• Şimşek G, Güler T, Çiftçi M, Ertaş ON ve Dalkılıç B. Esans yağ karışımının (Kekik, Karanfil ve Anason) broylerlerde canlı ağırlık, karkas ve etlerin duyusal özellikleri üzerine etkisi. Yüzüncü Yıl Üniversitesi Veteriner Fakültesi Dergisi, 2005; 16(2): 1-5.
• Demir E, Kilinc K, Yildirim Y, Dincer F and Eseceli H. Comparative effects of mint, sage, thyme and flavomycin in wheat-based broiler diets. Archiva Zootechnica, 2008; 11: 54-63.
• Göksoy EO, Akşid M and Kırkan Ş. The effects of organic acid and origanum onites supplementations on some physical and microbial characteristics of broiler meat obtained from broilers kept under seasonal heat stres. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2010; 16 (Suppl-A):41-46. https://doi.org/10.9775/kvfd.2009.1280.
• Karimi A, Yan F, Coto C, Park JH, Min Y, Lu C, Gidden JO, Lay Jr and Waldroup PW. Effects of level and source of oregano leaf in starter diets for broiler chicks. Journal of Applied Poultry Research, 2010; 19: 137-145. https://doi.org/10.3382/japr.2009-00088.
• Roofchaee A, Irani M, Ebrahimzadeh MA and Akbari MR. Effect of dietary oregano (Origanum vulgare L.) essential oil on growth performance, cecal microflora and serum antioxidant activity of broiler chickens. African Journal of Biotechnology, 2011; 10: 6177-6183. https://doi.org/10.5897/AJB10.2596.
• Yaşar S, Namık D, Fatih G, and Gökçimen A, Selçuk K. Effects of inclusion of aeriel dried parts of some herbs in broiler diets. The Journal of Animal & Plant Sciences, 2011; 21(3): 465-476.
• Mountzouris KC, Paraskevas V, Tsirtsikos P, Palamidi I, Steiner T, Schatzmayr G and Fegeros K. Assessment of a phytogenic feed additive effect on broiler growth performance, nutrient digestibility and caecal microflora composition. Animal Feed Science and Technology, 2011; 168: 223-231. https://doi.org/10.1016/j.anifeedsci.2011.03.020.
• Hong JC, Steiner T, Aufy A and Lien TF. Effects of supplemental essential oil on growth performance, lipid metabolites and immunity, intestinal characteristics, microbiota and carcass traits in broilers. Livestock Science, 2012; 144: 253-262. https://doi.org/10.1016/j.livsci.2011.12.008.
• Bozkurt M, Tokuşoğlu Ö, Küçükyılmaz K, Aksit H, Çabuk M, Çatlı AU, Seyrek K and Çınar M. Effects of dietary manan oligosaccharide and herbal essential oil blend supplementation on performance and oxidative stability of eggs and liver in laying hens. Italian Journal of Animal Science, 2012; 11: e41. https://doi.org/10.4081/ijas.2012.e41.
• Mathlouthi N, Bouzaienne T, Oueslati I, Recoquillay F, Hamdi M, Urdaci M and Bergaoui R. Use of rosemary, oregano, and a commercial blend of essential oils in broiler chickens: in vitro antimicrobial activities and effects on growth performance. Journal of Animal Science, 2012; 90: 813-823. https://doi.org/10.2527/jas.2010-3646.
• Topbaş S. Etlik piliç yemlerine karvakrol esaslı farklı esansiyel yağların katılmasının büyüme performansı ve bazı kesim özellikleri üzerine etkilerinin belirlenmesi. Fen Bilimleri Enstitüsü Zootekni Anabilim Dalı. Doktora Tezi, 2014; 43 s.
• Feizi A, Bijanzad P and Kaboli K. Effects of thyme volatile oils on performance of broiler chickens. European Journal of Experimental Biology, 2013; 3: 250-254.
• Abdel-Wareth AAA, Kehraus S, Hippenstiel F and Südekum KH. Effects of thyme and oregano on growth performance of broilers from 4 to 42 days of age and on microbial counts in crop, small intestine and caecum of 42-day-old broilers. Animal Feed Science and Technology, 2012; 178: 198-202. https://doi.org/10.1016/j.anifeedsci.2012.10.006.
• Eleroğlu H, Yıldırım A, Şekeroğlu A and Duman M. Comparison of the growth performance and carcass characteristics of two slow-growing broiler genotypes fed diets supplemented with dry oregano (Origanum vulgare L.) or lemon balm (Melissa officinalis L.) leaves under the organic system. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2014; 20: 49-58. https://doi:10.9775/kvfd.2013.9444.
• Mohiti-Asli M and Ghanaatparast-Rashti M. Dietary oregano essential oil alleviates experimentally induced coccidiosis in broilers. Preventive Veterinary Medicine, 2015; 120: 195-202.
• Pirmohamammadi A, Daneshyar M, Farhoomand P, Aliakbarlu J and Hamian F. Effects of Thymus vulgaris and Mentha pulegium on colour, nutrients and peroxidation of meat in heat-stressed broilers. South African Journal of Animal Science, 2016; 46: 278-284. https://doi.org/10.4314/sajas.v46i3.7.
• Bozkurt M, Ege G, Aysul N, Akşit H, Tüzün AE, Küçükyılmaz K, Borum AE, Uygun M, Akşit D, Aypak S, Şimşek E, Seyrek K, Koçer B, Bintaş E and Orojpour A. Effect of anticoccidial monensin with oregano essential oil on broilers experimentally challenged with mixed Eimeria spp. Poultry Science, 2016; 95:1858–1868. http://dx.doi.org/10.3382/ps/pew077.
• Ri CS, Jiang XR, Kim MH, Wang J, Zhang HJ, Wu SG, Bontempo V and Qi GH. Effects of dietary oregano powder supplementation on the growth performance, antioxidant status and meat quality of broiler chicks. Italian Journal of Animal Science, 2017; 16: 246-252. https://doi.org/10.1080/1828051X.2016.1274243.
• Wade MR, Manwar SJ, Kuralkar SV, Waghmare SP, Ingle VC and Hajare SW. Effect of thyme essential oil on performance of broiler chicken. Journal of Entomology and Zoology Studies, 2018; 6(3): 25-28.
• Vlaicu PA, Panaite TD, Olteanu M, Turcu RP, Saracila M and Criste RD. Effect of the dietary oregano (Origanum vulgare L.) powder and oil on the performance, carcass and organs development of broilers reared under heat stress (32°C). Lucrari Ştiintifice-Universitatea de Ştiinte Agricole Şi Medicina Veterinara, Seria Zootehnie, 2018; 69: 207-213.
• Vlaicu PA, Panaite TD, Turcu RP and Tabuc C. Dietary Origanum vulgare supplements for broilers. Romanian Biotechnological Letters, 2020; 25(5):1922-1929. https://doi.org/10.25083/rbl/25.5/1922.1929.
• Köksal BH and Küçükersan MK. Broyler rasyonlarına humat ile bitki ekstraktı karışımı ilavesinin büyüme performansı, bazı bağışıklık ve serum biyokimya değerlerine etkileri. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2012; 18: 103-108. https://doi.org/10.9775/kvfd.2011.5114.
• Case GL, He L, Mo H and Elson CE. Induction of geranyl pyrophosphate pyrophosphatase activity by cholesterol‐suppressive isoprenoids. Lipids, 1995; 30: 357-359. https://doi.org/10.1007/BF02536045.
• Govaris A, Botsoglou N, Papageorigia G, Botsoglou E and Ambrosiadis I. Dietary versus post-mortem use of oregano oil and/or alpha-tocopherol in turkeys to inhibit development of lipid oxidation in meat during refrigerated storage. International Journal of Food Sciences and Nutrition, 2004; 55(2): 115-23.
• Nikolaos A, Botsoglou N, Govaris A, Botsoglou E, Grigoropoulou S and Papageorigia G. Antioxidant Activity of Dietary Oregano Essential Oil and -Tocopheryl Acetate Supplementation in Long-Term Frozen Stored Turkey Meat. Journal of Agricultural and Food Chemistry, 2003; 51(10): 2930-2936.
• Zaazaa A, Mudalal S, Alzuheir I, Samara M, Jalboush N, Fayyad A and Petracci M. The Impact of Thyme and Oregano Essential Oils Dietary Supplementation on Broiler Health, Growth Performance, and Prevalence of Growth-Related Breast Muscle Abnormalities. Animals, 2022; 12(21): 3065. https://doi.org/10.3390/ani12213065.
• Salama AM, Belih, SS and Khedr NE. Influence of dietary oregano plant extract supplementation on growth performance and economic efficiency of broiler chicks. Benha Veterinary Medical Journal, 2023; 44: 15-19. https://doi.org/10.21608/bvmj.2023.210639.1661.
• García-García, JH, Salinas-Chavira J, Benavides-González F, Corona-Barrera E, Romero-Treviño EM and Loredo-Osti J. Productive performance and carcass characteristics of broiler chickens fed on diets with different protein, energy levels, and essential oils during the warm season in dry tropics. Animals, 2024; 14: 3179. https://doi.org/10.3390/ ani14223179.
• Madkour M, Alaqaly AM, Soliman SS, Ali SI and Aboelazab O. Growth performance, blood biochemistry, and mRNA expression of hepatic heat shock proteins of heat-stressed broilers in response to rosemary and oregano extracts. Journal of Thermal Biology, 2024; 119: 103791. https://doi.org/10.1016/j.jtherbio.2024.103791
• Bozkurt M, Bintaş E, Kırkan Ş, Akşit H, Küçükyılmaz K, Erbaş G, Çabuk M, Akşit D, Parın U, Ege G, Koçer B, Seyrek K and Tüzün AE. Comparative evaluation of dietary supplementation with mannan oligosaccharide and oregano essential oil in forced molted and fully fed laying hens between 82 and 106 weeks of age. Poultry Science, 2016; 95:2576–2591. http://dx.doi.org/10.3382/ps/pew140.
• Gül M, Yılmaz E, Sezmiş G, Apaydın Yıldırım B, Kaya A and Önel SE. Effect of oregano (Oreganum syriacum L.) essential oil and cage density on performance parameters, egg quality criteria, some blood biochemical parameters, blood antioxidant capacity, and intestinal histopathology in laying hens. GSC Biological and Pharmaceutical Sciences, 2020; 13(02): 136-145. https://doi.org/10.30574/gscbps.2020.13.2.0370.
• Gao F, Zhang L, Li H, Xia F, Bai H, Piao X, Sun Z, Cui H and Shi L. Dietary oregano essential oil supplementation influences production performance and gut microbiota in late-phase laying hens fed wheat-based diets. Animals, 2022; 12:3007. https:// doi.org/10.3390/ani12213007.
• Johnson AM, Anderson G, Arguelles-Ramos M and Ali AAB. Effect of dietary essential oil of oregano on performance parameters, gastrointestinal traits, blood lipid profile, and antioxidant capacity of laying hens during the pullet phase. Frontiers in Veterinary Science, 2022; 3: 1072712. https://doi.org/10.3389/fanim.2022.1072712.
• Denli M, Okan F and Uluocak AN. Effect of dietary suplementation of herb essential oils on the growth performance, carcass and intestinal characteristics of Quail (Coturnix coturnix japonica). South African Journal of Animal Science, 2004; 34(3): 174-179.
• Parlat SS, Yıldız AÖ, Olgun O and Cufadar Y. Bıldırcın rasyonlarinda büyütme amaçlı antibiyotiklere alternatif olarak kekik uçucu yağı (Origanum Vulgare L.) kullanımı. Selcuk Journal of Agriculture and Food Sciences, 2005; 19: 7-12.
• Çetingul IS, Bayram I, Yardımcı M, Şahin EH, Sengor E, Akkaya AB and Uyarlar C. Effects of oregano (Oregano Onites) on performance, hatchability and egg quality parameters of laying quails (Coturnix coturnix japonica). Italian Journal of Animal Science, 2009; 8: 467-477. https://doi.org/10.4081/ijas.2009.467.
• Ruan D, Fan Q, Fouad AM, Sun Y, Huang S, Wu A, Lin C, Kuang Z, Zhang C and Jiang S. Effects of dietary oregano essential oil supplementation on growth performance, intestinal antioxidative capacity, immunity, and intestinal microbiota in yellow-feathered chickens. Journal of Animal Science, 2021; 99 (2): skab033. https://doi.org/10.1093/jas/skab033.
• Eleroğlu H ve Yıldırım A. Organik sistemde kuru kekik (Origanum vulgare l.) yaprağı ilave edilmiş karma yemle beslenen beç tavuklarının (Numida meleagris) refah parametreleri. Journal of Poultry Research, December 2019; 16(2):74-79. https://doi:10.34233/jpr.654870.
• Sivropoulo A, Kokkini S, Lanaras T and Arsenakis M. Antimicrobial activity of mint essantial oils. Journal of Agricultural and Food Chemistry, 1995; 43: 2384-2388.
• Dimitrijevic SI, Mihajlovski KR, Antonovic DG, Milanovic-Stevanovic MR and Mijin DZ. A study of the synergistic antilisterial effects of a sub-lethal dose of lactic acid and essential oils from Thymus vulgaris L., Rosmarinus officinalis L. and Origanum vulgare L., Food Chemistry, 2007; 104: 774–782.
• Ropadiar. 2011a [cited 2011]. Available from: http://www.plantapharm.com.tr/urunlerimiz/ropafeed/ropadiar.
• Ekonext 30. 2011b [cited 2011]. Available from: http://www.ekolgida.com/urun.php?id=676.
• Özkan G, Sağdıç O and Özcan M. Inhibition of pathogenic bacteria by essential oils at different concentrations. Food Science and Technology International, 2003; 9(2): 85–88.