Araştırma Makalesi

Dupuytren's Contracture: A 10-Year Retrospective Study

Cilt: 51 Sayı: 2 28 Ağustos 2025
PDF İndir
EN TR

Dupuytren's Contracture: A 10-Year Retrospective Study

Öz

Dupuytren’s contracture is a progressive, benign fibroproliferative disease characterized by abnormal collagen accumulation in the palmar region of the hand and flexor surfaces of the fingers. This study retrospectively reviewed 257 patients who underwent surgery at our clinic between January 2014 and December 2024 using electronic hospital records. The analysis focused on age, sex, number of operated hands, affected fingers, annual surgical distribution, skin closure techniques, and comorbidities. Among the 257 patients, 24 underwent bilateral surgery, and five required reoperation due to recurrence, resulting in a total of 286 operated hands. The study cohort consisted of 196 male and 61 female patients. Bilateral surgery was performed in 21 male and three female patients, while five male patients required a second operation due to recurrence. The mean age of the patients was 60 years (range: 34-83). In 73.4% of cases, both the hand and fingers were affected, while 25.8% had isolated palmar involvement. The fourth finger was the most frequently affected (78.5%), followed by the fifth finger (57.6%). Z-plasty was used for skin closure in 222 out of 286 operated hands. This study aims to explore the risk factors associated with Dupuytren’s contracture and contribute to the understanding of its prevalence in our region, enhancing regional data.

Anahtar Kelimeler

Kaynakça

  1. 1. Khaliq F, Orji C. Dupuytren’s Contracture: A Review of the Literature. Cureus. 2024;16(12):e74945. doi:10.7759/ cureus.74945
  2. 2. Şakı MC, Ersen B, Tunalı O, Aksu İ, Kahveci R. Dupuytren Kontraktürü: 87 Olgunun Retrospektif İncelenmesi. Uludağ Üniversitesi Tıp Fakültesi Derg. 2014;40(1):19-21.
  3. 3. Lurati AR. Dupuytren’s Contracture. Work Heal Saf. 2017;65(3):96-99. doi:10.1177/2165079916680215 Dupuytren's Contracture
  4. 4.Elmelegy NG, Nader D. The importance of multiple Z- plasty- assisted physical therapy in the treatment of Dupuytren’scontracture. J Orthop Surg Res. 2025;20(1).doi:10.1186/s13018-024-05387-3
  5. 5.Hindocha S, John S, Stanley JK, Watson SJ, Bayat A. TheHeritability of Dupuytren’s Disease: Familial Aggregation andIts Clinical Significance. J Hand Surg Am. 2006;31(2):204-210. doi:10.1016/J.JHSA.2005.09.018
  6. 6.Thorne CH. Grabb and Smith’s Plastic Surgery. In: FreshwaterM.felix. Dupuytren’s Disease, 6th edition. Philadelphia:Lippincott Williams & Wilkins, a Wolters Kluwer business; 2007.864-868.
  7. 7.Dolmans GH, Werker PM, Hennies HC, et al. Wnt Signalingand Dupuytren’s Disease. N Engl J Med. 2011;365(4):307-317. doi:10.1056/nejmoa1101029
  8. 8.ten Dam EJPM, van Beuge MM, Bank RA, Werker PMN.Further evidence of the involvement of the Wnt signalingpathway in Dupuytren’s disease. J Cell Commun Signal. 2016;10(1):33-40. doi:10.1007/s12079-015-0312-8

Ayrıntılar

Birincil Dil

İngilizce

Konular

Cerrahi (Diğer)

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

28 Ağustos 2025

Gönderilme Tarihi

10 Mart 2025

Kabul Tarihi

2 Temmuz 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 51 Sayı: 2

Kaynak Göster

APA
Kastamoni, M., Çeçen, S., Özgenel, G. Y., Akın, S., Okan, M. U., Yılmaz, K., & Gümüş, O. A. (2025). Dupuytren’s Contracture: A 10-Year Retrospective Study. Journal of Uludağ University Medical Faculty, 51(2), 217-221. https://doi.org/10.32708/uutfd.1650479
AMA
1.Kastamoni M, Çeçen S, Özgenel GY, vd. Dupuytren’s Contracture: A 10-Year Retrospective Study. Uludağ Tıp Derg. 2025;51(2):217-221. doi:10.32708/uutfd.1650479
Chicago
Kastamoni, Menekşe, Süleyman Çeçen, Güzin Yeşim Özgenel, vd. 2025. “Dupuytren’s Contracture: A 10-Year Retrospective Study”. Journal of Uludağ University Medical Faculty 51 (2): 217-21. https://doi.org/10.32708/uutfd.1650479.
EndNote
Kastamoni M, Çeçen S, Özgenel GY, Akın S, Okan MU, Yılmaz K, Gümüş OA (01 Ağustos 2025) Dupuytren’s Contracture: A 10-Year Retrospective Study. Journal of Uludağ University Medical Faculty 51 2 217–221.
IEEE
[1]M. Kastamoni vd., “Dupuytren’s Contracture: A 10-Year Retrospective Study”, Uludağ Tıp Derg, c. 51, sy 2, ss. 217–221, Ağu. 2025, doi: 10.32708/uutfd.1650479.
ISNAD
Kastamoni, Menekşe - Çeçen, Süleyman - Özgenel, Güzin Yeşim - Akın, Selçuk - Okan, Mehmet Uğur - Yılmaz, Kadir - Gümüş, Osman Alperen. “Dupuytren’s Contracture: A 10-Year Retrospective Study”. Journal of Uludağ University Medical Faculty 51/2 (01 Ağustos 2025): 217-221. https://doi.org/10.32708/uutfd.1650479.
JAMA
1.Kastamoni M, Çeçen S, Özgenel GY, Akın S, Okan MU, Yılmaz K, Gümüş OA. Dupuytren’s Contracture: A 10-Year Retrospective Study. Uludağ Tıp Derg. 2025;51:217–221.
MLA
Kastamoni, Menekşe, vd. “Dupuytren’s Contracture: A 10-Year Retrospective Study”. Journal of Uludağ University Medical Faculty, c. 51, sy 2, Ağustos 2025, ss. 217-21, doi:10.32708/uutfd.1650479.
Vancouver
1.Menekşe Kastamoni, Süleyman Çeçen, Güzin Yeşim Özgenel, Selçuk Akın, Mehmet Uğur Okan, Kadir Yılmaz, Osman Alperen Gümüş. Dupuytren’s Contracture: A 10-Year Retrospective Study. Uludağ Tıp Derg. 01 Ağustos 2025;51(2):217-21. doi:10.32708/uutfd.1650479

ISSN: 1300-414X, e-ISSN: 2645-9027

Uludağ Üniversitesi Tıp Fakültesi Dergisi "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License" ile lisanslanmaktadır.


Creative Commons License
Journal of Uludag University Medical Faculty is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

2023