EN
TR
An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves
Öz
In this study, structural changes caused by acute effects of STZ induced diabetes on peripheral nerves were investigated with electron microscope. Twenty four male Wistar Albino rats were divided into 4 groups: control, sham, 15 days and 30 days diabetic groups. Nothing applied to control group; sodium citrate, as STZ solvent, to Sham group and 45 mg/kg STZ solved in sodium citrate to diabetic group. 15 and 30 days after injections, rats were sacrified under high dose anesthesia, and sciatic nerves were extracted for electron microscopic examination. A evident gap between perineurium and nerve fibres were observed in both 15 and 30 days diabetic groups. And in 30 days group, myelin sheath degenerations were more obvious in myelinated nerve fibres. On the other hand, Schwann cells and unmyelinated nerve fibres appeared normal. Consequently, STZ induced diabetes were seen to cause degenerative changes in n. ischiadicus and those changes were more evident in 30 days diabetic group.
Anahtar Kelimeler
Ayrıntılar
Birincil Dil
İngilizce
Konular
-
Bölüm
-
Yayımlanma Tarihi
1 Eylül 2006
Gönderilme Tarihi
1 Eylül 2006
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2006 Cilt: 32 Sayı: 3
APA
Karabay, G., Zağyapan, R., & Take, G. (2006). An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves. Journal of Uludağ University Medical Faculty, 32(3), 77-81. https://izlik.org/JA99DZ62MK
AMA
1.Karabay G, Zağyapan R, Take G. An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves. Uludağ Tıp Derg. 2006;32(3):77-81. https://izlik.org/JA99DZ62MK
Chicago
Karabay, Gülten, Ragıba Zağyapan, ve Gülnur Take. 2006. “An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves”. Journal of Uludağ University Medical Faculty 32 (3): 77-81. https://izlik.org/JA99DZ62MK.
EndNote
Karabay G, Zağyapan R, Take G (01 Eylül 2006) An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves. Journal of Uludağ University Medical Faculty 32 3 77–81.
IEEE
[1]G. Karabay, R. Zağyapan, ve G. Take, “An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves”, Uludağ Tıp Derg, c. 32, sy 3, ss. 77–81, Eyl. 2006, [çevrimiçi]. Erişim adresi: https://izlik.org/JA99DZ62MK
ISNAD
Karabay, Gülten - Zağyapan, Ragıba - Take, Gülnur. “An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves”. Journal of Uludağ University Medical Faculty 32/3 (01 Eylül 2006): 77-81. https://izlik.org/JA99DZ62MK.
JAMA
1.Karabay G, Zağyapan R, Take G. An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves. Uludağ Tıp Derg. 2006;32:77–81.
MLA
Karabay, Gülten, vd. “An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves”. Journal of Uludağ University Medical Faculty, c. 32, sy 3, Eylül 2006, ss. 77-81, https://izlik.org/JA99DZ62MK.
Vancouver
1.Gülten Karabay, Ragıba Zağyapan, Gülnur Take. An Ultrastructural Study of Effects of Streptozotocin Induced Diabetes on Rats Peripheral Nerves. Uludağ Tıp Derg [Internet]. 01 Eylül 2006;32(3):77-81. Erişim adresi: https://izlik.org/JA99DZ62MK
