Postoperatif Radyoterapi İle Eş Zamanlı Kapesitabin Uygulanan Lokal İleri Evre Rektum Kanserli Olgularda Etkinlik ve Tolerabilite Değerlendirilmesi

Cilt: 35 Sayı: 1 1 Mart 2009
  • Sevilcan Aygün
  • Meral Kurt
  • Sibel Kahraman Çetintaş
  • Eda Bengi Yılmaz
  • Huriye Öztürk
  • Şenay Kaplan
  • Lütfi Özkan
Uludağ Üniversitesi Tıp Fakültesi Dergisi Kapak
Uludağ Üniversitesi Tıp Fakültesi Dergisi
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The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer

Öz

The purpose of this study was to evaluate the efficacy and the toxicity of concomitant chemoradiotherapy (CRT) with capecitabine in cases with locally advanced rectal cancer. 26 cases with stage II-III rectal adenocarcinoma, treated with postoperative CRT with capecitabine at Uludag University Faculty of Medicine Radiotherapy Center, between March 2004-January 2007, were evaluated retrospectively. The radiotherapy was delivered with a boost dose of 50.4-54 Gray (Gy) totally and capecitabine was given median 1650 mg/m²/day (range, 1300- 1650). The median 2- year overall survival (OS) was 80%, and during the median follow-up time of 19 months (range, 1-30) there was no locoregional recurrence. Grade 3 leucopenia and diarrhea were observed in one (4%) and two (8%) cases, respectively. Although the insufficiency of follow-up time and the number of cases, we concluded that the concomitant postoperative chemoradiotherapy with capecitabine may be an effective and tolerabl treatment in locally advanced rectal cancer.

Anahtar Kelimeler

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Sevilcan Aygün Bu kişi benim

Meral Kurt Bu kişi benim

Sibel Kahraman Çetintaş Bu kişi benim

Eda Bengi Yılmaz Bu kişi benim

Huriye Öztürk Bu kişi benim

Şenay Kaplan Bu kişi benim

Lütfi Özkan Bu kişi benim

Yayımlanma Tarihi

1 Mart 2009

Gönderilme Tarihi

1 Mart 2009

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2009 Cilt: 35 Sayı: 1

IZ

https://izlik.org/JA29WH68AR

Kaynak Göster

RIS / Bibtex
APA
Aygün, S., Kurt, M., Çetintaş, S. K., Yılmaz, E. B., Öztürk, H., Kaplan, Ş., & Özkan, L. (2009). The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer. Journal of Uludağ University Medical Faculty, 35(1), 21-25. https://izlik.org/JA29WH68AR
AMA
1.Aygün S, Kurt M, Çetintaş SK, vd. The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer. Uludağ Tıp Derg. 2009;35(1):21-25. https://izlik.org/JA29WH68AR
Chicago
Aygün, Sevilcan, Meral Kurt, Sibel Kahraman Çetintaş, vd. 2009. “The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer”. Journal of Uludağ University Medical Faculty 35 (1): 21-25. https://izlik.org/JA29WH68AR.
EndNote
Aygün S, Kurt M, Çetintaş SK, Yılmaz EB, Öztürk H, Kaplan Ş, Özkan L (01 Mart 2009) The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer. Journal of Uludağ University Medical Faculty 35 1 21–25.
IEEE
[1]S. Aygün vd., “The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer”, Uludağ Tıp Derg, c. 35, sy 1, ss. 21–25, Mar. 2009, [çevrimiçi]. Erişim adresi: https://izlik.org/JA29WH68AR
ISNAD
Aygün, Sevilcan - Kurt, Meral - Çetintaş, Sibel Kahraman - Yılmaz, Eda Bengi - Öztürk, Huriye - Kaplan, Şenay - Özkan, Lütfi. “The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer”. Journal of Uludağ University Medical Faculty 35/1 (01 Mart 2009): 21-25. https://izlik.org/JA29WH68AR.
JAMA
1.Aygün S, Kurt M, Çetintaş SK, Yılmaz EB, Öztürk H, Kaplan Ş, Özkan L. The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer. Uludağ Tıp Derg. 2009;35:21–25.
MLA
Aygün, Sevilcan, vd. “The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer”. Journal of Uludağ University Medical Faculty, c. 35, sy 1, Mart 2009, ss. 21-25, https://izlik.org/JA29WH68AR.
Vancouver
1.Sevilcan Aygün, Meral Kurt, Sibel Kahraman Çetintaş, Eda Bengi Yılmaz, Huriye Öztürk, Şenay Kaplan, Lütfi Özkan. The Evaluation of Efficacy and Tolerability of Postopertative Concomittant Chemoradiation With Capecitabine in Cases With Locally Advanced Rectal Cancer. Uludağ Tıp Derg [Internet]. 01 Mart 2009;35(1):21-5. Erişim adresi: https://izlik.org/JA29WH68AR

ISSN: 1300-414X, e-ISSN: 2645-9027

Uludağ Üniversitesi Tıp Fakültesi Dergisi "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License" ile lisanslanmaktadır.


Creative Commons License
Journal of Uludag University Medical Faculty is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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