DOSIMETRIC COMPARISON OF 3 DIMENSIONAL CONFORMAL RADIOTHERAPY (3DCRT) AND VOLUMETRIC MODULATED ARC THERAPY (VMAT) TECHNIQUE IN CASES OF DIAGNOSED THORACIC ESOPHAGEAL CANCER PATIENTS: A RETROSPECTIVE STUDY

Yıl 2018, , 117 - 124, 01.08.2018

Habibe Altaş , Meral Kurt , Sema Gözcü Tunç , Sibel Kahraman Çetintaş Candan Demiröz Abakay Burcu İbicioğlu , Ece Ayfer Cura Abdulhamit Turan

https://doi.org/10.32708/uutfd.431755

Öz

3BKRT and VMAT techniques used in radiotherapy
treatment of esophageal cancer to see the effects of protecting risk organs
while achieving target volume and obtain their own data, to compare there
retrospective dosimetric results with each other. For This study; 10 patient thoracic
esophageal cancer patients were selected that treated with curative
radiotherapy. Plans were prepared  the
fraction would be 1,8 Gy and totally 54 Gy. 
Critical organs, CI and HI were compared between two techniques. As a
result of the statistical comparisons showed no significant difference between
3BKRT and VMAT except for HI (p = 0,010) in the analysis of  the values of PTV54. For OAR doses; value of
the lung V₁₀ was found to be supeior to the 3BKRT technique
(p=0,017). The V₄₀ value of the heart was found to be low in the
VMAT technique (p = 0.002). Additionally,
for spinal cord D_max value, VMAT technique has lower values than 3BKRT
(p = 0.001).  As  results of our study, although both
techniques could be used in terms of dose homogenity and risk of organs, the use
of  VMAT technique might be preferable to
consider of the comorbidities affecting these older patients.

Anahtar Kelimeler

Esophageal cancer, radiotherapy, VMAT, 3DCRT

Toraks Yerşimli Özofagus Kanseri Tanılı Olgularda 3 Boyutlu Konformal Radyoterapi (3BKRT) ve Hacimsel Ayarlı Ark Terapi (Vmat) Tekniğinin Dozimetrik Karşılaştırması: Retrospektif Çalışma

Öz

Özofagus kanserinin radyoterapi ile tedavisinde
kullanılan 3BKRT ve VMAT tekniklerinin hedef hacmi sararken riskli organları
korumadaki etkilerini görmek ve kendi verilerini elde etmek; elde ettiğimiz bu
retrospektif dozimetrik sonuçları birbirleriyle karşılaştırmaktır. Bu çalışma için; 10 küratif radyoterapi
ile tedavi edilen toraks yerleşimli özofagus kanseri tanılı hasta seçildi. Fraksiyon
dozu 1,8 Gy ve toplam doz 54 Gy olacak şekilde planlar hazırlandı. İki teknik arasında
kritik organ dozu (OAR), CI ve HI karşılaştırıldı. Yapılan istatistiksel karşılaştırma sonucunda PTV54’e ait
değerlerin analizinde 3BKRT ve VMAT arasında HI (p=0,010)  dışında anlamlı fark görülmemiştir. OAR
dozları için; akciğerin V₁₀ değeri  3BKRT tekniğinde üstün bulunmuştur (p=0,017).
Kalbin V₄₀ değeri VMAT tekniğinde düşük bulunmuştur (p=0,002). Ayrıca,
Spinal Cord D_max değeri için bakıldığında VMAT tekniği 3BKRT’ye göre
düşük değerlere sahiptir (p=0,001). Çalışmamızın sonucunda doz homojenliği ve riskli
organlar açısından her iki teknikte kullanılabilir görülmesine rağmen ileri yaştaki
bu hastalarda etki eden komorbiditeler göz önüne alındığında VMAT tekniği
kullanımının tercih olabileceği görülmüştür.

Anahtar Kelimeler

Özofagus kanseri, radyoterapi, VMAT, 3BKRT

Kaynakça

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