Erişkin Hastalarda Akut Bakteriyel Tonsillit Tanısını Öngörmede Mutlak Nötrofil Sayısının (MNS) Kullanımı

Öz

Tonsillit; tüm dünyada en sık görülen hastalıklardan olup, hastalığın bakteriyel veya viral kökenli olduğunu saptamak kimi zaman çok zor olabilir. Bu çalışmada, ‘’Mutlak Nötrofil Sayısının (MNS)’’  akut bakteriyel tonsillit tanısını öngörmede prediktör olarak kullanılıp kullanılamayacağı araştırılmak istenmiştir. Çalışma Mayıs 2015-  Mayıs 2016 tarihleri arasında boğaz ağrısı, ateş ve odinofaji şikayetleri ile değerlendirilen 42 hasta üzerinden yürütülmüştür. Kan testleri ve boğaz kültürleri uygulanmış ve MNS her hasta için tedavi başlamadan önce hesaplanmıştır. Lökosit sayısı ve MNS, pozitif boğaz kültürü olan 26 hastada istatistiksel olarak anlamlı şekilde yüksek bulunmuştur(p<0,001). Buna ek olarak; MNS≥6.82 olması  %92.3 sensitivite ve %93.7 spesifite ile pozitif boğaz kültürü sonuçlarının varlığını istatistiksel olarak anlamlı olacak şekilde öngörmüştür(p<0,001). Bu bilgiler ışığında MNS’ nin kolay uygulanabilir, hızlı ve güvenilir bir prediktör olarak akut bakteriyel tonsillit tanısında yüksek sensitivite ve spesifite ile kullanılabileceği ve yüksek MNS düzeyi olan hastalara boğaz kültürü sonucu beklenmeden antibiyotik tedavisinin başlanması önerilmektedir.

Anahtar Kelimeler

• Mutlak nötrofil sayısı,prediktör,boğaz kültürü,tonsillit

Usage of Absolute Neutrophil Count (ANC) as A Predictor for Acute Bacterial Tonsillitis in Adult Patients

Öz

Tonsillitis is a very common disease all over the world and it can be confusing to detect if it has bacterial or viral origin. In this study, it was aimed to investigate if absolute neutrophil count (ANC) can be used as a predictor to display acute bacterial tosillitis.42 patients with the complaints of sore throat, fever and odynophagia were examined by the physician between May 2015 and May 2016. Supporting blood tests and throat cultures were performed and ANC was calculated for all patients individually before the initiaiton of treatment. White blood cell count (WBCC) and ANC were significantly higher in 26 patients with positive throat culture (p<0.001). Moreover, it was detected that ANC ≥ 6.82 was able to predict positive culture results with %92.3 sensitivity and %93.7 specificity which was also statistically significant (p<0.001).According to this, ANC can be used as an easy, fast and reliable predictor for acute bacterial tonsillitis with high sensitivity and specifity. In this sense, patients with high ANC can be treated with antibiotics without waiting for culture results.

Anahtar Kelimeler

• Absolute neutrophil count,predictor,throat culture,tonsillitis

Kaynakça

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