A DOSIMETRIC STUDY OF INTENSITY MODULATED AND THREE DIMENSIONAL CONFORMAL RETRO-ORBITAL RADIOTHERAPY PLANS OF GRAVES OPHTHALMOPTHY DIAGNOSED PATIENTS

Yıl 2018, Cilt: 44 Sayı: 2, 75 - 81, 01.08.2018

Duygu Bolat Sibel Kahraman Çetintaş Sema Gözcü Tunç Meral Kurt , Candan Demiröz Abakay Oğuz Aydın , Habibe Altaş

https://doi.org/10.32708/uutfd.418437

Öz

In
the treatment of Graves Ophthalmopthy (GO) with radiotherapy, we aimed to compare
the doses of target volume and critical organs by using mutual lateral three
dimensional conformal radiotherapy (3DCRT) and intensity
modulated radiotherapy (IMRT) techniques.

            In this study,
two separete treatment plans were develepod with 3DCRT radiotherapy and IMRT
with a fraction dose of 2 Gy and the total doses of 20 Gy in 15 patients with GO
diagnosis. The dose values of the planned target volume (PTV) and critical
organs were compared and homogeneity index (HI), conformity index (CI) values
were calculated and Monitor Unit (MU) values were eveluated.

            There was no difference between two techniques at D_95%
(p=0,583) of PTV; D_98% (p<0,001) took advantege of in IMRT
technique.

            As a result; it can be said that the 3DCRT technique used
for the lateral angle of the patient wants to avoid the doses that cause cataract.

Anahtar Kelimeler

Graves ophthalmopthy, Intensity Modulated Radiotherapy, Orbit Radiotherapy, Three Dimensional Conformal Radiotherapy

Graves Oftalmopati Tanılı Olguların Yoğunluk Ayarlı ve Üçboyutlu Konformal Retro-Orbital Radyoterapi Planlarının Dozimetrik Olarak İncelenmesi

Öz

Graves
oftalmopati (GO) tanılı olguların radyoterapi ile tedavisinde; karşılıklı
lateral üç boyutlu konformal radyoterapi (3BKRT) ve yoğunluk ayarlı radyoterapi
(YART) teknikleri kullanılarak hedef hacmin ve riskli organların aldığı
dozların karşılaştırılması amaçlanmıştır.

Çalışmada; GO tanılı 15 hastaya fraksiyon
dozu 2 Gy toplam doz 20 Gy olacak şekilde 3BKRT ve YART tekniği ile iki ayrı
tedavi planı oluşturuldu. Planlanan hedef hacmin (PTV) ve riskli
organların aldığı doz değerleri karşılaştırıldı ve homojenite indeksi (HI),
konformite indeksi (CI) değerleri hesaplanıp Monitor Unit (MU) değerlerine
bakıldı.

PTV’nin D_95% (p=0,583) değerinde iki teknik arasında fark görülmedi; D_98%
(p<0,001) değerinde YART tekniğinin üstünlüğü görüldü.

Sonuç
olarak; hastanın katarakt olmasına
neden olabilecek dozlardan kaçınmak istendiğinden, kullanılan
karşılıklı lateral açıdan dolayı
3BKRT tekniğinin daha düşük doz radyasyon aldığı söylenebilir.

Anahtar Kelimeler

Graves Oftalmopatisi, Orbita Radyoterapisi, Üç Boyutlu Konformal Radyoterapi, Yoğunluk Ayarlı Radyoterapi

Kaynakça

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