Cerrahi Menopozda Oral ve Transdermal Östrojen Tedavilerinin Hastaların Psikolojik Durumları ve Cinsel Fonksiyonları Üzerine Etkisi

Yıl 2018, Cilt: 44 Sayı: 3, 153 - 158, 01.12.2018

Fatih Yılmaz Alparslan Baksu

https://doi.org/10.32708/uutfd.425479

Öz

Cerrahi
menopozun hastaların psikolojik durum ve cinsel fonksiyonlara etkisi ve
tedavisi halen tartışmalıdır. Bu amaçla transabdominal histerektomi ve
bilateral salpingooferektomi (TAH+BSO) geçiren hastalarda oral ve transdermal
östrojen tedavilerinin psikolojik durumlar ve cinsel fonksiyonlar üzerine
etkilerini karşılaştırdık. Çalışmamızda benign endikasyonlarla TAH+BSO yapılan
52 hasta rastgele randomizasyonla üç gruba ayrıldı. Ameliyattan 12 hafta sonra 18
hastaya oral östrojen (grup 1), 17 hastaya transdermal östrojen (grup 2)
başlandı. 17 hastadan oluşan kontrol grubuna (grup 3) tedavi verilmedi. Hastalara
ameliyattan önce, 12 ve 28 hafta sonra Beck Depresyon İndeksi (BDI) ve Kadın Cinsel
Fonksiyon İndeksi (FSFI) uygulandı. Oral grupta tedavi sonrası psikolojik
durumlar ve cinsel fonksiyonlar üzerine olumlu yanıt gözlenirken transdermal
grupta değişiklik gözlenmedi. Kontrol grubunda ameliyat öncesi ve sonrası
arasında değişiklik olmadı.  Bu
sonuçlarla çalışmamızda cerrahi menopozun hastaların psikolojik durum ve cinsel
fonksiyonları üzerine değişiklik görülmezken oral östrojen tedavisinin olumlu
etkileri görülmüştür. 

Anahtar Kelimeler

Anahtar Kelimeler: Cerrahi menopoz, Psikolojik durum, Cinsel fonksiyon, Östrojen etkisi

The Effect of Oral and Transdermal Estrogen Therapy on the Psychological Situations and Sexual Functions of Patients in Surgical Menopause

Öz

The effect and treatment of
psychopathological conditions and sexual functions of surgically menopausal
patients is still controversial. For this purpose, we compared the effects of
oral and transdermal estrogen treatments on psychological status and sexual
function in patients who underwent transabdominal hysterectomy and bilateral salpingo-oophorectomy
(TAH + BSO). In our study, 52 patients who underwent TAH + BSO with benign
indications were randomly assigned to three groups. Twelve weeks after the
operation, 17 patients were not treated as a control group (group 1), 18
patients were given oral estrogen (group 2) and 17 patients were transdermal
estrogen (group 3). Beck Depression
Index (BDI) and Female Sexual Function Index (FSFI) were administered before
operation, 12 and 28 weeks after operation. There was no change in
preoperative and postoperative results in group 1. In group 2, there was a
positive response to psychological conditions and sexual functions after
treatment, but no change in group 3 was observed. As a result of our study, it was observed that positive effects of oral
estrogen therapy could be seen when there was no effect on the psychological
status and sexual functions of surgical menopausal patients.

Anahtar Kelimeler

Surgical menopause, Psychological condition, Sexual function, Estrogen replacement terapy

Kaynakça

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