Erişkin Hastalarda Akut Bakteriyel Tonsillit Tanısını Öngörmede Mutlak Nötrofil Sayısının (MNS) Kullanımı

Yıl 2019, Cilt: 45 Sayı: 2, 145 - 149, 01.08.2019

Murat Sertan Şahin , Ömer Afşın Özmen

https://doi.org/10.32708/uutfd.455628

Öz

Tonsillit;
tüm dünyada en sık görülen hastalıklardan olup, hastalığın bakteriyel veya
viral kökenli olduğunu saptamak kimi zaman çok zor olabilir. Bu çalışmada,
‘’Mutlak Nötrofil Sayısının (MNS)’’  akut
bakteriyel tonsillit tanısını öngörmede prediktör olarak kullanılıp
kullanılamayacağı araştırılmak istenmiştir. Çalışma Mayıs 2015-  Mayıs 2016 tarihleri arasında boğaz ağrısı,
ateş ve odinofaji şikayetleri ile değerlendirilen 42 hasta üzerinden
yürütülmüştür. Kan testleri ve boğaz kültürleri uygulanmış ve MNS her hasta
için tedavi başlamadan önce hesaplanmıştır. Lökosit sayısı ve MNS, pozitif
boğaz kültürü olan 26 hastada istatistiksel olarak anlamlı şekilde yüksek
bulunmuştur(p<0,001). Buna ek olarak; MNS≥6.82 olması  %92.3 sensitivite ve %93.7 spesifite ile pozitif
boğaz kültürü sonuçlarının varlığını istatistiksel olarak anlamlı olacak
şekilde öngörmüştür(p<0,001). Bu bilgiler ışığında MNS’ nin kolay
uygulanabilir, hızlı ve güvenilir bir prediktör olarak akut bakteriyel
tonsillit tanısında yüksek sensitivite ve spesifite ile kullanılabileceği ve
yüksek MNS düzeyi olan hastalara boğaz kültürü sonucu beklenmeden antibiyotik
tedavisinin başlanması önerilmektedir.

Anahtar Kelimeler

Mutlak nötrofil sayısı, prediktör, boğaz kültürü, tonsillit

Usage of Absolute Neutrophil Count (ANC) as A Predictor for Acute Bacterial Tonsillitis in Adult Patients

Öz

Tonsillitis
is a very common disease all over the world and it can be confusing to detect
if it has bacterial or viral origin. In this study, it was aimed to investigate
if absolute neutrophil count (ANC) can be used as a predictor to display acute bacterial
tosillitis.42 patients with the complaints of sore throat, fever and odynophagia
were examined by the physician between May 2015 and May 2016. Supporting blood
tests and throat cultures were performed and ANC was calculated for all
patients individually before the initiaiton of treatment. White blood cell
count (WBCC) and ANC were significantly higher in 26 patients with positive
throat culture (p<0.001). Moreover, it was detected that ANC ≥ 6.82 was able
to predict positive culture
results with %92.3 sensitivity and %93.7 specificity which was also statistically
significant (p<0.001).According to this, ANC can be used as an
easy, fast and reliable predictor for acute bacterial tonsillitis with high sensitivity
and specifity. In this sense, patients with high ANC can be treated with
antibiotics without waiting for culture results.

Anahtar Kelimeler

Absolute neutrophil count, predictor, throat culture, tonsillitis

Kaynakça

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