Araştırma Makalesi
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Yıl 2020, Cilt: 13 Sayı: COVID-19 Özel Sayı, 19 - 28, 29.09.2020

Öz

Destekleyen Kurum

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Proje Numarası

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Teşekkür

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Kaynakça

  • Referans 1. Zhou Y, Yang Y, Huang J, Jiang S, Du L. Advances in MERS-CoVVaccines and TherapeuticsBased on the Receptor-Binding Domain. Viruses. 2019 Jan 14;11(1).
  • Referans 2. Chen Y, Liu Q, Guo D. Emergingcoronaviruses: genomestructure, replication, and pathogenesis. J medvirol 2020.
  • Referans 3. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novelcoronavirus from patients with pneumonia in China, N Engl J Med 2020.
  • Referans 4. COVID-19 (SARS-CoV2) Enfeksiyonu Rehberi (Bilim Kurulu Çalışması). T.C. Sağlık Bakanlığı. Halk Sağlığı Genel Müdürlüğü. T.C. Sağlık Bakanlığı. (https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf) Erişim Tarihi: 14 Nisan 2020.
  • Referans 5. Novel CPERE. The epidemiologicalcharacteristics of an outbreak of 2019 novelcoronavirus diseases (COVID-19) in China. Zhonghua liuxingbingxuezazhi= Zhonghua liuxingbingxuezazhi. 2020; 41(2): 145.
  • Referans 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novelcoronavirus in Wuhan, China. The Lancet 2020; 395(10223):497-506.
  • Referans 7. World Health Organization. Clinical management of severe acute respiratoryinfection (SARI) when COVID-19 disease is suspected. InterimGuidance, 2020. Erişim Tarihi: 5 Nisan 2020. WHO Reference number WHO/2019-nCoV/clinical/2020.4
  • Referans 8. Jin YH, Cai L, Cheng ZS, Cheng H, Deng T, Fan YP, et al., for the Hospital of Wuhan University NovelCoronavirus Management and Research Team, Evidence-Based Medicine Chapter of China International Exchange and Promotive Association for Medical and Health Care (CPAM). A rapid advice guideline for the diagnosis and treatment of 2019 NovelCoronavirus (2019-nCoV) infectedpneumonia (Standard Version). Mil Med Res. 2020;7(1):4.
  • Referans 9. General Office of National Health Committee. Office of State Administration of Traditional Chinese Medicine. Notice on the issuance of a programme for the diagnosis and treatment of novelcoronavirus (2019-nCoV) infectedpneumonia (Trial Version 4). 2020.http://bgs.satcm.gov.cn/ zhengcewenjian/2020-01-28/12576.html. Erişim tarihi: 29 Ocak 2020.
  • Referans 10. Bernheim A, Mei X, Huang M, Yang Y, Fayad ZA, Zhang N, et al. Chest CT findings in coronavirus disease-19 (COVID-19): Relationship to duration of infection. Radiology 2020.
  • Referans 11. Madjid M, Safavi-Naeini P, Solomon SD, Vardeny O. Potential effects of coronaviruses on the cardiovascular system a review. JAMA Cardiol. 2020 doi:10.1001/jamacardio.2020.1286.
  • Referans 12. Wenzhong L, Hualan L. COVID-19: atacks the beta-1 chain of hempglobincaptures the porphyrin to inhibit human hememetobolism. ChemRxiv. 2020. https://chemrxiv.org/articles/COVID19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173.
  • Referans 13. Handbook of COVID-19 Prevention and Treatment. Liang T. 18/March/2020. https://www.alnap.org/help-library/handbook-of-covid-19-prevention-and-treatment
  • Referans 14. Xu H, Huang S, Liu S, Deng J, Jiao B, Ai L, et al. Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 duringhomecare with isolation: A new retrospective analysis based on O2O. Available at SSRN 3548746, 2020.
  • Referans 15. Bornstein SR, Dalan R, Hopkins D, Mingrone G, Boehm BO. Endocrine and metabolic link to coronavirusinfection. NatRevEndocrinol. 2020; doi: 10.1038/s41574-020-0353-9.
  • Referans 16. Yin S, Huang M, Li D, Tang N. Difference of coagulationfeatures between severe pneumonia induced by SARS-CoV-2 and non-SARS-CoV-2. J ThrombThrombolysis. 2020. doi: 10.1007/s11239-020-02105-8.
  • Referans 17. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al., for the China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020; doi:10.1056/NEJMoa2002032.
  • Referans 18. Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RTPCR test results in patients recovered from COVID-19. JAMA 2020.
  • Referans 19. Song F, Shi N, Shan F, Zhang Z, Shen J, Lu H, et al. Emergingcoronavirus 2019-nCoV pneumonia. Radiology. 2020; doi:10.1148/radiol.2020200274.
  • Referans 20. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) Outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020.
  • Referans 21. Özcan H, Elkoca A, Yalçın Ö. COVID-19 Enfeksiyonu ve Gebelik Üzerindeki Etkileri. Anadolu Kliniği Tıp Bilimleri Dergisi, Ocak 2020;25, 1. DOI: 10.21673/anadoluklin.708151.
  • Referans 22. İnal İnce D, Vardar Yağlı N, Sağlam M, Çalık Kütükcü E. COVID-19 Enfeksiyonunda Akut ve Post-Akut Fizyoterapi ve Rehabilitasyon. Turk J PhysiotherRehabil. 2020; 31(1):81-93. doi: 10.21653/tjpr.718877.
  • Referans 23. https://www.aa.com.tr/tr/koronavirus/turkiyede-ilk-plazma-tedavisi-uygulanan-kovid-19-hastasi-iyilesti/1821009

Evaluation of Patients Diagnosed with COVID-19

Yıl 2020, Cilt: 13 Sayı: COVID-19 Özel Sayı, 19 - 28, 29.09.2020

Öz

Aim: This study was conducted to share our experiences, analyses and results related to patients diagnosed with COVID-19 with the aim of contributing to the literature in the diagnosis and treatment of and the combat against the COVID-19 disease. Here, we report the epidemiological, clinical, laboratory and radiological characteristics of COVID-19 patients as well as their treatments and clinical outcomes.
Method: This study was conducted as a descriptive and epidemiological study. We included patients admitted to the secondary step public hospital in Kahramanmaras, affiliated with the Ministry of Health, and who were evaluated, followed-up and treated for diagnosed of COVID-19. The patients' data such as age, gender, complaints, blood test results, imaging findings, PCR results and prognosis were recorded.
Results: 73 patients diagnosed with COVID-19 were examined. 42.5% of the patients were aged 60 and over. The most complaints of the patients diagnosed with COVID-19, were cough, fever and shortness of breath.57% of the patients had lymphocytopenia, and 42.3% had hypocalcemia.
Conclusion: While the typical symptoms are crucial in patients applying for COVID-19, healthcare workers should also pay attention to atypical symptoms. The PCR test is primarily used in the diagnosis of COVID-19, but detecting compatibility with COVID-19 in CT of the thorax is more effective in diagnosis. COVID-19 patients have high D-dimer, CRP, PCT and ferritin levels and low lymphocyte levels. Most patients were observed to have a good general condition, with low overall mortality rates. The main issue in combatting COVID-19 is isolation and hygiene conditions.

Proje Numarası

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Kaynakça

  • Referans 1. Zhou Y, Yang Y, Huang J, Jiang S, Du L. Advances in MERS-CoVVaccines and TherapeuticsBased on the Receptor-Binding Domain. Viruses. 2019 Jan 14;11(1).
  • Referans 2. Chen Y, Liu Q, Guo D. Emergingcoronaviruses: genomestructure, replication, and pathogenesis. J medvirol 2020.
  • Referans 3. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novelcoronavirus from patients with pneumonia in China, N Engl J Med 2020.
  • Referans 4. COVID-19 (SARS-CoV2) Enfeksiyonu Rehberi (Bilim Kurulu Çalışması). T.C. Sağlık Bakanlığı. Halk Sağlığı Genel Müdürlüğü. T.C. Sağlık Bakanlığı. (https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf) Erişim Tarihi: 14 Nisan 2020.
  • Referans 5. Novel CPERE. The epidemiologicalcharacteristics of an outbreak of 2019 novelcoronavirus diseases (COVID-19) in China. Zhonghua liuxingbingxuezazhi= Zhonghua liuxingbingxuezazhi. 2020; 41(2): 145.
  • Referans 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novelcoronavirus in Wuhan, China. The Lancet 2020; 395(10223):497-506.
  • Referans 7. World Health Organization. Clinical management of severe acute respiratoryinfection (SARI) when COVID-19 disease is suspected. InterimGuidance, 2020. Erişim Tarihi: 5 Nisan 2020. WHO Reference number WHO/2019-nCoV/clinical/2020.4
  • Referans 8. Jin YH, Cai L, Cheng ZS, Cheng H, Deng T, Fan YP, et al., for the Hospital of Wuhan University NovelCoronavirus Management and Research Team, Evidence-Based Medicine Chapter of China International Exchange and Promotive Association for Medical and Health Care (CPAM). A rapid advice guideline for the diagnosis and treatment of 2019 NovelCoronavirus (2019-nCoV) infectedpneumonia (Standard Version). Mil Med Res. 2020;7(1):4.
  • Referans 9. General Office of National Health Committee. Office of State Administration of Traditional Chinese Medicine. Notice on the issuance of a programme for the diagnosis and treatment of novelcoronavirus (2019-nCoV) infectedpneumonia (Trial Version 4). 2020.http://bgs.satcm.gov.cn/ zhengcewenjian/2020-01-28/12576.html. Erişim tarihi: 29 Ocak 2020.
  • Referans 10. Bernheim A, Mei X, Huang M, Yang Y, Fayad ZA, Zhang N, et al. Chest CT findings in coronavirus disease-19 (COVID-19): Relationship to duration of infection. Radiology 2020.
  • Referans 11. Madjid M, Safavi-Naeini P, Solomon SD, Vardeny O. Potential effects of coronaviruses on the cardiovascular system a review. JAMA Cardiol. 2020 doi:10.1001/jamacardio.2020.1286.
  • Referans 12. Wenzhong L, Hualan L. COVID-19: atacks the beta-1 chain of hempglobincaptures the porphyrin to inhibit human hememetobolism. ChemRxiv. 2020. https://chemrxiv.org/articles/COVID19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173.
  • Referans 13. Handbook of COVID-19 Prevention and Treatment. Liang T. 18/March/2020. https://www.alnap.org/help-library/handbook-of-covid-19-prevention-and-treatment
  • Referans 14. Xu H, Huang S, Liu S, Deng J, Jiao B, Ai L, et al. Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 duringhomecare with isolation: A new retrospective analysis based on O2O. Available at SSRN 3548746, 2020.
  • Referans 15. Bornstein SR, Dalan R, Hopkins D, Mingrone G, Boehm BO. Endocrine and metabolic link to coronavirusinfection. NatRevEndocrinol. 2020; doi: 10.1038/s41574-020-0353-9.
  • Referans 16. Yin S, Huang M, Li D, Tang N. Difference of coagulationfeatures between severe pneumonia induced by SARS-CoV-2 and non-SARS-CoV-2. J ThrombThrombolysis. 2020. doi: 10.1007/s11239-020-02105-8.
  • Referans 17. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al., for the China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020; doi:10.1056/NEJMoa2002032.
  • Referans 18. Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RTPCR test results in patients recovered from COVID-19. JAMA 2020.
  • Referans 19. Song F, Shi N, Shan F, Zhang Z, Shen J, Lu H, et al. Emergingcoronavirus 2019-nCoV pneumonia. Radiology. 2020; doi:10.1148/radiol.2020200274.
  • Referans 20. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) Outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020.
  • Referans 21. Özcan H, Elkoca A, Yalçın Ö. COVID-19 Enfeksiyonu ve Gebelik Üzerindeki Etkileri. Anadolu Kliniği Tıp Bilimleri Dergisi, Ocak 2020;25, 1. DOI: 10.21673/anadoluklin.708151.
  • Referans 22. İnal İnce D, Vardar Yağlı N, Sağlam M, Çalık Kütükcü E. COVID-19 Enfeksiyonunda Akut ve Post-Akut Fizyoterapi ve Rehabilitasyon. Turk J PhysiotherRehabil. 2020; 31(1):81-93. doi: 10.21653/tjpr.718877.
  • Referans 23. https://www.aa.com.tr/tr/koronavirus/turkiyede-ilk-plazma-tedavisi-uygulanan-kovid-19-hastasi-iyilesti/1821009
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Orijinal Araştırma Makaleleri
Yazarlar

Muhammed Semih Gedik 0000-0003-3854-4794

Hakan Hakkoymaz 0000-0002-8568-8283

Nuri Basan Bu kişi benim 0000-0003-3179-8150

Proje Numarası -
Yayımlanma Tarihi 29 Eylül 2020
Gönderilme Tarihi 22 Mayıs 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 13 Sayı: COVID-19 Özel Sayı

Kaynak Göster

APA Gedik, M. S., Hakkoymaz, H., & Basan, N. (2020). Evaluation of Patients Diagnosed with COVID-19. Van Sağlık Bilimleri Dergisi, 13(COVID-19 Özel Sayı), 19-28.

ISSN 

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