Robotik Cerrahi ile Tedavi Edilen Erken Evre Endometrium Kanserli Obez Hastalarda: Tek Merkezli Bir Analiz

Yıl 2022, Cilt: 15 Sayı: 3, 254 - 259, 30.12.2022

Osman Köse , Orhan Ünal , Koray Gök , Mehmet Sühha Bostancı , Selçuk Özden , Nermin Akdemir

https://doi.org/10.52976/vansaglik.1102639

Öz

Amaç: Robotik cerrahi ile opere edilen obez endometrium kanserli hastaların intraoperatif ve postoperatif sonuçlarını değerlendirmek.
Materyal-Metot: Bu çalışmada, 2015'den 2018'ye kadar tek bir merkezde erken evre endometrium kanser için robotik cerrahi uygulanan obez kadınların retrospektif olarak değerlendirildi. Temel demografik özellikler ve perioperatif dönem sonuçları tıbbi kayıtlardan çıkarıldı ve değerlendirildi.
Bulgular: çalışmaya alınan 44 hastanın yaş ortalaması 59,23±9,41yıl ve vücut kitle indeksi ortalaması 36,38±5,09 olarak bulundu. Olguların %79.1’i Grade 1, %20.9’i Grade 2 Endometrium Kanseri tanısı aldı. Vakaların ortalama tümör çapları 4,58±2,36 cm olarak bulundu. Hiçbir olguda ameliyat sırasında ya da sonrasında herhangi ciddi bir komplikasyon yaşanmazken ve kan transfüzyonu gereksinim olmadı.
Sonuç: Endometrium kanserli obez hastalarda robotik cerrahi yaklaşım uygulanabilir ve güvenli bir yöntem olarak görülmektedir.

Anahtar Kelimeler

Robotik Cerrahi, Endometrium Kanseri, Obezite

Destekleyen Kurum

yok

Proje Numarası

YOK

Kaynakça

• Al Sawah E, Salemi JL, Hoffman M, Imudia AN, Mikhail E. Association between Obesity, Surgical Route, and Perioperative Outcomes in Patients with Uterine Cancer. Minim Invasive Surg. 2018 Jun 19;2018:5130856. doi: 10.1155/2018/5130856. PMID: 30018822; PMCID: PMC6029454.
• Backes FJ, Brudie LA, Farrell MR, Ahmad S, Finkler NJ, Bigsby GE, O'Malley D, Cohn DE, Holloway RW, Fowler JM. Short- and long-term morbidity and outcomes after robotic surgery for comprehensive endometrial cancer staging. Gynecol Oncol. 2012 Jun;125(3):546-51. doi: 10.1016/j.ygyno.2012.02.023. Epub 2012 Mar 3. PMID: 22387522.
• Boggess JF, Gehrig PA, Cantrell L, et al. A comparative study of 3 surgical methods for hysterectomy with staging for endometrial cancer: robotic assistance, laparoscopy, laparotomy. Am J Obstet Gynecol 2008; 199: 360.e1-9.
• Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med. 2003 Apr 24;348(17):1625-38. doi: 10.1056/NEJMoa021423. PMID: 12711737.
• Cardenas-Goicoechea J, Adams S, Bhat SB, Randall TC. Surgical outcomes of robotic-assisted surgical staging for endometrial cancer are equivalent to traditional laparoscopic staging at a minimally invasive surgical center. Gynecol Oncol. 2010 May;117(2):224-8. doi: 10.1016/j.ygyno.2010.01.009. Epub 2010 Feb 7. PMID: 20144471; PMCID: PMC2896309.
• Corrado G, Vizza E, Cela V, Mereu L, Bogliolo S, Legge F, Ciccarone F, Mancini E, Gallotta V, Baiocco E, Monterossi G, Perri MT, Zampa A, Pasciuto T, Scambia G. Laparoscopic versus robotic hysterectomy in obese and extremely obese patients with endometrial cancer: A multi-institutional analysis. Eur J Surg Oncol. 2018; S0748-7983(18)31296-4
• Cusimano MC, Simpson AN, Dossa F, Liani V, Kaur Y, Acuna SA, Robertson D, Satkunaratnam A, Bernardini MQ, Ferguson SE, Baxter NN. Laparoscopic and robotic hysterectomy in endometrial cancer patients with obesity: a systematic review and meta-analysis of conversions and complications. Am J Obstet Gynecol. 2019 Nov;221(5):410-428.e19. doi: 10.1016/j.ajog.2019.05.004. Epub 2019 May 10. PMID: 31082383
• Diaz-Arrastia C, Jurnalov C, Gomez G, Townsend C Jr. Laparoscopic hysterectomy using a computer-enhanced surgical robot. Surg Endosc. 2002 Sep;16(9):1271-3. doi: 10.1007/s00464-002-8523-5. Epub 2002 Jun 27. PMID: 12085153.
• Everett E, Tamimi H, Greer B, et al. The effect of body mass index on clinical/pathologic features, surgical morbidity, and outcome in patients with endometrial cancer. Gynecol Oncol 2003; 90: 150-7.
• Furau A, Tit DM, Furau C, Bungau S, Furau G, Toma MM, Cirstoveanu CG, Petre I, Todor DS, Romosan RS, Craina M. Analysis of the Impact of Comorbidities on Endometrial Lesions Using the Charlson Comorbidity Index in Western Romania. Medicina (Kaunas). 2021 Sep 8;57(9):945. doi: 10.3390/medicina57090945. PMID: 34577868; PMCID: PMC8469351
• Gracia M, García-Santos J, Ramirez M, Bellón M, Herraiz MA, Coronado PJ. Value of robotic surgery in endometrial cancer by body mass index. Int J Gynaecol Obstet. 2020 Sep;150(3):398-405. doi: 10.1002/ijgo.13258. Epub 2020 Jun 22. PMID: 32506474
• Grieco DL, Anzellotti GM, Russo A, Bongiovanni F, Costantini B, D'Indinosante M, Varone F, Cavallaro F, Tortorella L, Polidori L, Romanò B, Gallotta V, Dell'Anna AM, Sollazzi L, Scambia G, Conti G, Antonelli M. Airway Closure during Surgical Pneumoperitoneum in Obese Patients. Anesthesiology. 2019 Jul;131(1):58-73. doi: 10.1097/ALN.0000000000002662. PMID: 3088247
• J.L. Walker, et al., Surgical staging of uterine cancer: randomized phase III trial of laparoscopy vs laparotomy- a Gynecologic Oncology Group Study (GOG): preliminary results, J. Clin. Oncol. 24 (18) (2006). p. 258s-258s.
• King LJ, Young AJ, Nagar PM, McDowell JL, Smith AL. Outcomes of robotic surgery in morbidly obese patients with endometrial cancer: a retrospective study. J Robot Surg. 2021 Jul 18. doi: 10.1007/s11701-021-01277-6. Epub ahead of print. PMID: 34278543.
• Leitao MM, Narain WR, Boccamazzo D, Sioulas V, Cassella D, Ducie JA, Eriksson AG, Sonoda Y, Chi DS, Brown CL, Levine DA, Jewell EL, Zivanovic O, Barakat RR, Abu-Rustum NR, Gardner GJ. Impact of Robotic Platforms on Surgical Approach and Costs in the Management of Morbidly Obese Patients with Newly Diagnosed Uterine Cancer. Ann Surg Oncol. 2016 Jul;23(7):2192-8. doi: 10.1245/s10434-015-5062-6. Epub 2016 Jan 7. PMID: 26744108; PMCID: PMC4891264.
• Pavelka JC, Ben-Shachar I, Fowler JM, Ramirez NC, Copeland LJ, Eaton LA, Manolitsas TP, Cohn DE. Morbid obesity and endometrial cancer: surgical, clinical, and pathologic outcomes in surgically managed patients. Gynecol Oncol. 2004 Dec;95(3):588-92. doi: 10.1016/j.ygyno.2004.07.047. PMID: 15581968.
• Peiretti M, Zanagnolo V, Bocciolone L, et al. Robotic surgery: changing the surgical approach for endometrial cancer in a referral cancer center. J Minim Invasive Gynecol 2009; 16: 427-31.
• Reynolds RK, Burke WM, Advincula AP. Preliminary experience with robot-assisted aparoscopic staging of gynecologic malignancies. JSLS 2005; 9: 149-58.
• Seamon LG, Cohn DE, Henretta MS, Kim KH, Carlson MJ, Phillips GS, Fowler JM. Minimally invasive comprehensive surgical staging for endometrial cancer: Robotics or laparoscopy? Gynecol Oncol. 2009 Apr;113(1):36-41. doi: 10.1016/j.ygyno.2008.12.005. Epub 2009 Jan 24. PMID: 19168206
• Suidan RS, He W, Sun CC, Zhao H, Fleming ND, Ramirez PT, Soliman PT, Westin SN, Lu KH, Giordano SH, Meyer LA. Impact of body mass index and operative approach on surgical morbidity and costs in women with endometrial carcinoma and hyperplasia. Gynecol Oncol. 2017 Apr;145(1):55-60. doi: 10.1016/j.ygyno.2017.01.025. Epub 2017 Jan 26. PMID: 28131529; PMCID: PMC5557389.
• Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4. PMID: 33538338