Nephrological Problems in COVID19 Patients: A Retrospective Single Centre Study

Yıl 2024, Cilt: 17 Sayı: 2, 69 - 75, 30.08.2024

Ergin Karataş , Mehmet Erdem

https://doi.org/10.52976/vansaglik.1354802

Öz

Aim: The SARS CoV-2 virus that emerged in 2019 and the emerging pandemic are full of journeys. The nephrological effects of the pandemic have been a matter of curiosity. In this study, nephrological problems were investigated in COVID-19 positive patients hospitalized in clinical and intensive care units.
Materials and Methods: The research is an observational cross-sectional retrospective study. Between November 2020 and November 2021, blood and urine analyzes sent from patients aged 18-90 who were followed up in the COVID-19 Intensive Care Unit and COVID-19 clinics were examined. 79 patients were included in the study. The diagnosis of COVID-19 was made by considering RT-PCR, thorax CT and clinical situation. These 79 patients were compared in terms of acute kidney injury (AKI), electrolyte imbalance and complete urinalysis disorders.
Results: AKI was detected in 32.9% of patients. 42.3% of patients with AKI were female, 57.7% were male. 73.1% of the patients with AKI were hospitalized in the intensive care unit. Hematuria and proteinuria were detected in 65% and 27%, respectively. In the examinations performed, 65% hematuria, 27% proteinuria, 44% hyponatremia, 4% hypernatremia, 13% hypokalemia, 11% hyperkalemia, 11% hypophosphatemia, 6% hyperphosphatemia, 9% hypomagnesemia, 3% hypermagnesemia, 24% hypocalcemia and 65% hypoalbuminemia were detected.
Conclusion: Acute kidney injury, hematuria and proteinuria were statistically significant in patients diagnosed with COVID-19 and hospitalized and followed up. There are also electrolyte imbalances and hypoalbuminemia in patients. Follow-up of patients with COVID-19 should be carefully monitored in terms of nephrolog

Anahtar Kelimeler

COVID-19, AKI, Hematuria, Proteinuria, Electrolyte Imbalance

Etik Beyan

There are no conflict of interest.

Destekleyen Kurum

After approval by Van YYÜ Non-Interventional Clinical Research Ethics Committee on March 1, 2022,

Proje Numarası

174273

Teşekkür

We would like to extend special thanks to Yuzuncu Yil University Ethics Scientific Research Projects Coordination for their support. We would like to also thank all patients who participated in the study.

COVID-19 Hastalarında Nefrolojik Problemler: Retrospektif Tek Merkezli Çalışma

Öz

Amaç: 2019 yılında ortaya çıkan SARS CoV-2 virüsü ve meydana getirdiği pandemi tüm dünyayı etkisi altına almıştır. Pandeminin nefrolojik etkileri merak konusu olmuştur. Bu çalışmada klinik ve yoğun bakımda yatan COVID-19 pozitif hastalarda nefrolojik problemler araştırıldı.
Gereç ve Yöntem: Araştırma gözlemsel kesitsel retrospektif bir çalışmadır. Kasım 2020 –Kasım 2021 tarihleri arasında COVID-19 Yoğun Bakım Ünitesi ve COVID-19 kliniklerinde takip edilen 18-90 yaş arası hastalardan gönderilen kan ve idrar tahlilleri incelendi. Çalışmaya 79 hasta dahil edildi. COVID-19 tanısı, RT-PCR, toraks BT ve klinik durum gözetilerek konuldu. Bu 79 hastanın akut böbrek hasarı (ABH), elektrolit imbalansı ve tam idrar tetkiki bozuklukları açısından karşılaştırılması yapıldı. Ayrıca COVID-19 tanılı grupta hastaların yaş, cinsiyet bilgileri ve yattığı klinik açısından da karşılaştırması yapıldı.
Bulgular: Hastaların %32,9 unda ABH tespit edildi. ABH’ı olan hastaların %42,3’ü kadın, %57,7’si erkek idi. ABH’ı olan hastaların %73,1’i yoğun bakımda yatan hastalar idi. Yapılan tetkiklerde %65 hematüri, %27 proteinüri %44’ünde hiponatremi, %4’ünde hipernatremi, %13’ünde hipokalemi, %11 hiperkalemi, %11 hipofosfatemi, %6 hiperfosfatemi, %9 hipomagnezemi, %3 hipermagnezemi, %24 hipokalsemi ve %65 hipoalbuminemi tespit edildi.
Sonuç: COVID-19 tanısı alan ve yatırılıp takip ve tedavisi yapılan hastalarda ABH, hematüri ve proteinüri istatistiksel olarak anlamlı sonuç verdi. Ayrıca hastalarda elektrolit imbalansı ve hipoalbuminemi de mevcuttur. C0VİD-19 hastalarının takipleri nefrolojik açıdan dikkatle izlenmelidir.

Anahtar Kelimeler

COVID-19, ABH, Hematüri, Proteinüri, Elektrolit İmbalansı

Etik Beyan

There are no conflict of interest.

Destekleyen Kurum

After approval by Van YYÜ Non-Interventional Clinical Research Ethics Committee on March 1, 2022, under reference number 174273, the study was initiated.

Proje Numarası

174273

Teşekkür

We would like to extend special thanks to Yuzuncu Yil University Ethics Scientific Research Projects Coordination for their support. We would like to also thank all patients who participated in the study.

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