The Effects of Oral Progestagen Administration on the Fertility of Synchronized Goats During the Breeding Season

Öz

The objective of this study was to assess the impact of oral progesterone (altrenogest) administered after mating on fertility in goats synchronized during the breeding season. A total of 47 Hair goats were included in the study. A progesterone-impregnated intravaginal sponges were administered for 12 days. On day 10 of intravaginal sponge administration, 480 IU pregnant mare's serum gonadotropin (PMSG) and 0.075 mg cloprostenol were injected intramuscularly to the goats. Animals were exposed to bucks for 12 hours after detection of estrus by the foraging buck. The goats were randomly assigned to two distinct groups: Group 1 (G1, n=23) and Group 2 (G2, n=24). G1 goats were orally administrated 4.4 mg of altrenogest per day for 30 days after mating. G2 goats served as controls. Pregnancy examinations were performed by transrectal ultrasonography on the 30th and 42nd days after mating. Blood samples were taken from one day after mating to 30 days (3-day intervals). Statistical analysis comparing G1 and G2 revealed no significant differences between the groups regarding progesterone concentrations, conception rate, pregnancy rate, lambing rate, multiple birth rate, fecundity, and litter size (p>0.05). In conclusion, this study revealed that oral progesterone use had no impact on fertility parameters. Moreover, further research is warranted to explore the efficacy of various oral progesterone analogs.

Anahtar Kelimeler

• Fertility
• Goat
• Pregnancy
• Progesterone.

Destekleyen Kurum

Van Yüzüncü Yil University, Scientific Research Projects Coordination Unit

Proje Numarası

TSA-2017-5978

Etik Beyan

Ethical approval was received for this study from Van Yüzüncü Yıl University Animal Experiments Local Ethics Committee (Decision No: 2017/01) on 26.01.2017.

Üreme Sezonunda Oral Progestagen Uygulamasının Senkronize Keçilerin Fertilitesi Üzerine Etkileri

Öz

Bu çalışmanın amacı, üreme mevsiminde senkronize edilen keçilerde çiftleşmeden sonra uygulanan oral progesteronun (altrenogest) fertilite üzerindeki etkisini değerlendirmektir. Çalışmada, toplam 47 Kıl keçisi kullanıldı. Hayvanlara 12 gün boyunca progesteron emdirilmiş intravajinal süngerler uygulandı. Vajinal sünger uygulamasının 10. gününde 480 IU PMSG ve 0.075 mg kloprostenol intramüsküler olarak uygulandı. Östrüsdeki hayvanlar, arama tekesi ile tespit edildikten sonra 12 saat tekelere maruz bırakıldı. Keçiler rastgele iki ayrı gruba ayrıldı: Grup 1 (G1, n=23) ve Grup 2 (G2, n=24). G1 keçilerine çiftleşmeden sonraki 30 gün boyunca günde 4.4 mg altrenogest oral olarak uygulandı. G2 keçileri ise kontrol grubu olarak değerlendirildi. Gebelik muayeneleri çiftleşmeden sonraki 30. ve 42. günlerde transrektal ultrasonografi ile yapıldı. Kan örnekleri çiftleşmeden sonraki günden 30 güne kadar (3 günlük aralıklarla) alındı. G1 ve G2 arasında istatistiksel analiz, progesteron konsantrasyonları, konsepsiyon oranı, gebelik oranı, kuzulama oranı, çoklu doğum oranı, fekundite ve bir batındaki yavru sayısı açısından gruplar arasında anlamlı bir fark olmadığını ortaya çıkardı (p>0.05). Sonuç olarak, bu çalışmada oral progesteron kullanımının fertilite parametreleri üzerine herhangi bir etkisinin olmadığı tespit edildi. Ayrıca, çeşitli oral progesteron analoglarının etkinliğini araştırmak için daha fazla araştırmaya ihtiyaç vardır.

Anahtar Kelimeler

• Fertilite
• Gebelik
• Keçi
• Progesteron.

Proje Numarası

TSA-2017-5978

Kaynakça

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