Sağlıklı ve Kırığı olan Kedilerde D Vitamini, Kalsiyum, Fosfor ve Alkalen Fosfataz Değerlerinin Karşılaştırılması

Öz

Bu çalışmada sağlıklı ve kırık bulgusu olan kedilerde D vitamini, kalsiyum, fosfor ve alkalen fosfataz (ALP) değerlerinin belirlenmesi amaçlandı. Çalışmanın materyalini klinik olarak sağlıklı (kontrol grubu) 20 kedi ve kırık bulgusu olan 30 kedi (kırık grubu) olmak üzere toplam 50 kedi oluşturdu. Kedilerde kırıkların tespiti için klinik ve radyografik muayeneleri yapıldı ve ardından tüm hayvanlardan alınan kan örneklerinde D vitamini, ALP, fosfor ve kalsiyum değerleri ölçüldü. Bulgulara göre kırık grubundaki hayvanların D vitamini ortalamasının 22.47±0.65 ng/ml, kontrol grubunda ise 21.34±0.80 ng/ml olduğunu belirlendi. Kalsiyum ortalamaları kırık grubunda 4.88±0.25 mg/dL, kontrol grubunda 4.78±0.27 mg/dL; fosfor ortalamaları kırık grubunda 6.92±2.00 mg/dL, kontrol grubunda 8.99±3.30 mg/dL; ALP ortalamaları ise kırık grubunda 90.40±26.73 U/L, kontrol grubunda 91.35±28.54 U/L olarak bulundu. Sonuç olarak, kırığı bulunan hayvan ile sağlıklı kediler arasındaki D vitamini, kalsiyum, fosfor ve ALP değerlerinde istatistiksel bir fark bulunmamış ve bu değerlerin normal sınırlar içinde olduğu tespit edilmiştir.

Anahtar Kelimeler

• Alkalen fosfataz
• D vitamini
• Fosfor
• Kalsiyum
• Kedi
• Kırık

Comparison of Vitamin D, Calcium, Phosphorus and Alkaline Phosphatase Values in Healthy and Fractured Cats

Öz

This study aimed to determine the levels of vitamin D, calcium, phosphorus, and alkaline phosphatase (ALP) in healthy cats and cats with fractures. This study included a total of 50 cats, comprising 20 clinically healthy cats in the control group and 30 cats with fractures in the fracture group. Clinical and radiographic examinations were performed to diagnose fractures and blood samples were then collected from all animals to measure the levels of vitamin D, ALP, phosphorus, and calcium. According to the differences, the average vitamin D level in the fracture group was 22.47±0.65 ng/ml, while in the control group it was 21.34±0.80 ng/ml. The mean calcium levels were 4.88±0.25 mg/dL in the fracture group and 4.78±0.27 mg/dL in the control group; the mean phosphorus levels were 6.92±2.00 mg/dL in the fracture group and 8.99±3.30 mg/dL in the control group; and the mean ALP levels were 90.40±26.73 U/L in the fracture group and 91.35±28.54 U/L in the control group. In conclusion, no statistically significant difference were found in the vitamin D, calcium, phosphorus, and ALP values between the fractured animal and the healthy cats, and it was determined that these values were within normal limits.

Anahtar Kelimeler

• Alkaline Phosphatase
• Vitamin D
• Calcium
• Phosphorus
• Cat
• Fracture

Kaynakça

1. Alizadeh K, Ahmadi S, Sarchahi AA, Mohri M (2020). The effects of age, sex, breed, diet, reproductive status and housing condition on the amounts of 25 (OH) vitamin D in the serum of healthydogs: Reference values. Vet Med Sci, 8 (6), 2360-2366.
2. Amirnezhad S, Sheikhsarmast SA, Mohri M (2023). Serum concentration of 25-hydroxyvitamin D in apparently healthy cats regarding age, gender, breed, diet type, reproductive status, and housing condition. Iran J Vet Res, 24 (3), 265.
3. Backus RC, Ueda DC (2024). Age-dependentchanges in plasma concentrations of 25-hydroxy vitamin D may complicate vitamin D status assessment of immature cats. Front Vet Sci, 11, 1365204.
4. Bates JA (2008). Phosphorus: a quick reference. Vet Clin North Am Small Anim Pract, 38 (3), 471-475.
5. Beale BS (2004). Use of nutraceuticals and chondro protectants in osteoarthritic dogs and cats. Vet Clin: Small Anim Pract, 34 (1), 271-289.
6. Burr DB, Allen MR (2019). Basic and Applied Bone Biology. 2nd Eds. Academic Press. London. Canlı R, Çatalkaya E, Kanay BE et al. (2024). A retrospective study on the evaluation of hind limb bone fractures in cats. Int J Vet Anim Res, 7 (1), 7-11.
7. Cardoso CB, Rahal SC, Agostinho FS et al. (2016). Long bone fractures in cats: A retrospective study. Vet Zoo, 23 (3), 504-509.
8. Cummings SR, Black DM, Thompson DE et al. (1998). Effect of alendronate on risk of fracture in womenwithlow bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA, 280 (24), 2077-2082.

9. El-shafey S, El-Mezyen AEM, Behery A, Abd El Raouf M (2022). Tibial and fibular fractures in dogs and cats: retrospective study. Zagazig Vet J, 50 (1), 52-61.
10. Garnero P, Munoz, F, Sornay-Rendu E, Delmas PD (2007). Associations of vitamin D statuswith bone mineral density, bone turnover, bone loss and fracture risk in healthy post menopausal women. The OFELY study. Bone, 40 (3), 716-722.
11. Gerdhem P, Ringsberg KA, Obrant KJ, Akesson K (2005). Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women. Osteoporos Int, 16, 1425-1431.
12. Gülaydın A, Şındak N, Akgül, MB et al. (2024). Retrospective Analysis of Extremity Fractures in Cats: 288 Cases (2018-2023). Tr J Nature Sci, 13 (4), 148-152.
13. Harasen G (2009). Feline orthopedics. Can Vet J, 50, 669-670.
14. Jain R, Shukla BP, Nema S et al. (2018). Incidence of fracture in dog: a retro spective study. Vet Pract, 19 (1), 63-65.
15. Keosengthong A, Kampa N, Jitpean S et al. (2019). Incidence and classification of bone fracture in dogs and cats: a retrospective study at a Veterinary Teaching Hospital, Khon Kaen University, Thailand (2013-2016). Vet Integr Sci, 17 (2),127-39.
16. Kutsal GY, Özgüçlü E, Karahan S (2011). Post menapozal Osteoporotik Kadınlarda Giyim Tercihlerinin D vitamini ve Kemik Mineral Dansiteleri Üzerine Etkisi. Turk J Osteoporos, 17, 85-88.
17. Lalor SM, Mellanby RJ, Friend EJ et al. (2012). Domesticated cats with active mycobacteria infections have low serum vitamin D (25 (OH) D) concentrations. Transbound Emerg Dis, 59 (3), 279-281.
18. Mohiuddin M, Hasan MM, Shohag M et al. (2018). Surgical management of limb fractures in calves and goats. Bangladesh Vet J, 52 (1-4), 46-56.
19. Paskalev M, Krastev S, Filipov J (2005). Changes in some serum bone markers after experimental fracture and intramedullary osteomyelitis and osteosynthesis in dogs. Trakia J Sci, 3, 46-50.
20. Pineda C, Aguilera-Tejero E, Guerrero F et al. (2013). Mineral metabolism in growing cats: changes in thevalues of blood parameters with age. J Feline Med Surg, 15 (10), 866-871.
21. Slater JS, Anderson E (1994). Communication convergence in electronically supported discussions: An adaptation of Kincaid's convergence model. Telemat Inform, 11 (2), 111-125.
22. Sih TR, Morri JG, Hickman MA (2001). Chronic ingestion of high concentrations of cholecal ciferol in cats. Am J Vet Res, 62 (9), 1500-1506.
23. Sprinkle MC, Hooper SE, Backus RC (2018). Previously un described vitamin D C-3 epimer occurs in substantial amounts in the blood of cats. J Feline Med Surg, 20 (2), 83-90.
24. Titmarsh HF, Lalor SM, Tasker S et al. (2015). Vitamin D status in cats with feline immuno deficiency virus. Vet Med Sci, 1 (2), 72-78.
25. Turgut K (2000). Klinik enzimoloji, In: Veteriner Klinik Laboratuvar Teşhis, Bahçıvanlar Basımevi, Konya, Türkiye, pp; 180-201.
26. Vasileva R, Chaprazov T (2022). Long bone fractures in cats: a five-year retrospective study (2016-2020). Trakia J Sci, 20 (1), 45.
27. Yayla S, Altan S, Çatalkaya E, Kanay BE, Saylak N (2022). Evaluation of supra condylar femur fractures in cats: a retrospective study. Iran J Vet Sci Technol, 14 (4), 37-41.
28. Yurdakul İ, Bakır B (2017). Radiological and biochemical diagnosis of skeletal developmental disorders due to growth in Van Cats. Van Vet J, 28 (3), 131-136.