Araştırma Makalesi
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Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves

Yıl 2025, Cilt: 36 Sayı: 3, 199 - 204, 30.11.2025
https://doi.org/10.36483/vanvetj.1727292

Öz

Congenital cystic dermoids are rare developmental anomalies of the ocular surface in calves, potentially resulting in visual impairment, discomfort, or secondary infections if untreated. This retrospective study aimed to evaluate the clinical features, anatomical and positional classifications, surgical outcomes, and histopathological characteristics of congenital cystic dermoids in 17 calves (19 eyes). Medical records and histological data of excised tissues were reviewed. Lesions were anatomically classified as conjunctivocorneal (47.4%), conjunctival (36.8%), and conjunctivopalpebral (15.8%), and positionally based on their ocular surface location. Logistic regression analysis identified factors associated with surgical outcomes, categorized as “Good” or “Poor.” Temporal and ventrotemporal lesions were significantly associated with favorable outcomes (OR=1.64, p<0.05), while conjunctivocorneal and conjunctivopalpebral lesions were linked to poor prognosis (OR=0.49, p<0.05). Juvenil (OR=0.72, p<0.05) and concurrent signs such as epiphora, keratitis, and conjunctivitis (OR= 0.58, p<0.05) were also associated with worse prognosis. Right-eye involvement correlated with a better outcome (OR=1.63, p<0.05). Histopathological examinations revealed cystic structures lined by stratified squamous epithelium with keratin debris and inflammatory infiltration. Surgical approaches included conjunctivectomy, superficial keratectomy, and blepharoplasty, applied individually or in combination. Of the 19 eyes, 11 had good outcomes, 3 had poor outcomes, and 5 were undetermined due to incomplete follow-up. Poor outcomes were primarily associated with recurrence, ulceration, and persistent inflammation. In conclusion, lesion location, age, and clinical signs significantly influence prognosis. Optimizing outcomes in affected calves requires lesion-specific surgical strategies and tailored postoperative management.

Kaynakça

  • Abou-Rayyah Y, Rose GE, Konrad H, Chawla SJ, Moseley IF (2002). Clinical, radiological and pathological examination of periocular dermoid cysts: evidence of inflammation from an early age. Eye, 16, 507-512.
  • Abu-Romman, A., Scholand, K. K., Govindarajan, G et al. (2024). Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing. IOVS, 65 (5), 21.
  • Avcı N, Gümüş F, Özgermen B, Sağlam M (2024). A review of surgical cases of newborn calves. TJVR, 8 (2), 89-94.
  • Badanes Z, Ledbetter EC (2019). Ocular dermoids in dogs: A retrospective study, Vet Ophthalmol, 22, 760-766.
  • Barkyoumb SD, Leipold HW (1984). Nature and cause of bilateral ocular dermoids in Hereford cattle. Vet Pathol, 21, 316-324.
  • Barrantes Murillo DF, Rissi DR, Wiener DJ, Negrão Watanabe TT (2025). Feline dermoid cyst: Retrospective case series and literature review. Vet Pathol, 62 (3), 293-299.
  • Bekele T, Bhokre AP, Mekonnen B, Tesfaye W, Alemu B et al. (2014). Ocular dermoid in crossbred calf-A case report. Ethiop Vet J, 18, 105-108.
  • Castro JR, Hendrix DV, Van Amstel SR (2006). Ocular dermoids in cattle: a case report and review. AABP, 40, 8-12.
  • Cathelin A, Augsburger AS, Anne J et al. (2022). Ocular dermoids in 13 cats: a multicentre retrospective study. JFMS, 24, 745-753.
  • Gelatt KN (2014). Essentials of Veterinary Ophthalmology. 3rd rev edn. Gainesville: FL, USA.
  • Michelet D, Brasher C, Kaddour HB et al. (2017). Postoperative complications following neonatal and infant surgery: common events and predictive factors. Anaesthesia Critical Care & Pain Medicine, 36 (3), 163-169.
  • Kaushik AK, Kandavel H, Nalpathamkalam T, Pasman Y (2021). Bovine neonate is deficient in innate immunity at birth. Mol Immunol. 133, 101–109.
  • Khatun N, Bhaduri A, Debbarma S, Dewan SVP (2018). Ocular dermoid cyst in a calf and its surgical management. JEZS, 6, 433-34.
  • Kiliç N, Toplu N, Epikmen ET (2012). Surgical treatment of corneal large dermoid in a simmental calf. ASVS, 40, 1-5.
  • Morgan J, Curtis Shaw G, Weisman J, Cecere, T, Carvallo-Chaigneau FR (2025). Bilateral intraocular choristoma in a 2-day-old foal. JVDI, 10406387251324997.
  • Mosbah E, Awadin WF, Abass M (2022). A Survey on Congenital Head Malformations in Calves. JAVS, 7, 72-79.
  • Okur DT (2021). Dystocia due to dicephalus in a cow. Bozok Vet Sci, 2 (1), 4–5.
  • Pigatto JA, Cargnin LS, Melo AP et al. (2025). Epidemiological findings of ocular dermoid in dogs and cats: 50 cases (2007-2024). Pesq Vet, 45, e07509.
  • Pigatto JAT, Torikachvili M, Seibel MP et al. (2024). Conjunctival dermoid in a cat: case report. Arq Bras Med Vet Zootec 76 (06), e13200.
  • Sarrafzadeh-Rezaei F, Farshid AA, Saifzadeh S (2007). Congenital ocular dermoid cyst in a river buffalo (Bubalus bubalis) calf. J Vet Med, 54, 51-54.
  • Abdelfattah E, Fausak E, Maier G (2025). Failure of Passive Immune Transfer in Neonatal Beef Calves: A Scoping Review. Animals, 15 (14), 2072.
  • Shuleshko OO, Zhorina LV, Lieshchova MO (2023). Histopathology of the ocular dermoid in a bull of the Ukrainian grey breed (clinical case). Theor Appl Vet Med, 11(4), 22-26.
  • Singh KP (2015). Surgical correction of ocular dermoids in six dogs. Indian J Canine Pract, 7 (1).
  • Sosa E, Giannitti F, Macías-Rioseco M et al. (2025). Congenital neoplasms in cattle: A literature review and multi-institutional case series. JVDI, 10406387251324512.
  • Verma A, Sangwan V, Bansal N et al. (2022). A rare case of dermoid cyst associated with parotid gland in a male buffalo calf. Large Anim Rev, 28, 307-310.
  • Zhu J, Lan X, Mo K et al. (2024). Deficiency of SECTM1 impairs corneal wound healing in aging. Aging Cell, 23 (10), e14247.

17 Buzağıda Görülen Doğumsal Kistik Dermoidlerin Cerrahi Sonuçlarına Yönelik Retrospektif Bir Çalışma

Yıl 2025, Cilt: 36 Sayı: 3, 199 - 204, 30.11.2025
https://doi.org/10.36483/vanvetj.1727292

Öz

Doğumsal kistik dermoidler, buzağılarda göz yüzeyinde nadir görülen gelişimsel anomaliler olup, tedavi edilmedikleri takdirde görme bozukluklarına, rahatsızlığa veya ikincil enfeksiyonlara yol açabilir. Bu retrospektif çalışmanın amacı, 17 buzağıda (19 göz) görülen doğumsal kistik dermoidlerin klinik özelliklerini, anatomik ve pozisyonel sınıflandırmalarını, cerrahi sonuçlarını ve histopatolojik özelliklerini değerlendirmektir. Operasyonla uzaklaştırılan lezyonlara ait tıbbi kayıtlar ve histolojik veriler incelenmiştir. Lezyonlar anatomik olarak konjunktivokorneal (%47.4), konjunktival (%36.8) ve konjunktivopalpebral (%15.8) şeklinde sınıflandırılmış; ayrıca göz yüzeyindeki konumlarına göre pozisyonel olarak değerlendirilmiştir. Lojistik regresyon analizinde cerrahi sonuçlarla ilişkili faktörler incelenmiş ve sonuçlar “İyi” veya “Kötü” olarak kategorize edilmiştir. Temporal ve ventrotemporal yerleşimli lezyonlar iyi prognozla anlamlı şekilde ilişkili bulunmuştur (OR=1.64, p<0.05), buna karşılık konjunktivokorneal ve konjunktivopalpebral lezyonlar kötü prognozla ilişkili bulunmuştur (OR=0.49, p<0.05). Daha genç yaş (OR=0.72, p<0.05) ve epifora, keratit ile konjunktivit gibi eş zamanlı klinik bulguların varlığı (OR=0.58, p<0.05) da olumsuz prognostik göstergeler olarak belirlenmiştir. Sağ göz tutulumunun ise daha iyi cerrahi sonuçlarla ilişkili olduğu gözlemlenmiştir (OR=1.63, p<0.05). Histopatolojik incelemede, keratin artıkları ve iltihabi hücre infiltrasyonları içeren çok katlı yassı epitel ile döşeli kistik yapılar tespit edilmiştir. Cerrahi yöntemler arasında konjunktivektomi, yüzeyel keratektomi ve blefaroplasti yer almakta olup, bu teknikler bireysel olarak veya kombinasyon halinde uygulanmıştır. Toplam 19 gözün 11’inde iyi sonuçlar elde edilirken, 3’ünde kötü sonuçlar kaydedilmiş, 5’inde ise takip sürecinin tamamlanamaması nedeniyle sonuçlar belirlenememiştir. Kötü sonuçlar genellikle nüks, ülserasyon ve persistan inflamasyon ile ilişkilendirilmiştir. Sonuç olarak, lezyonun yerleşimi, buzağının yaşı ve eşlik eden klinik bulgular prognozu önemli ölçüde etkilemektedir. Etkilenen buzağılarda başarılı sonuçlar elde edebilmek için lezyona özgü cerrahi stratejiler ve bireyselleştirilmiş postoperatif yaklaşımlar gereklidir.

Kaynakça

  • Abou-Rayyah Y, Rose GE, Konrad H, Chawla SJ, Moseley IF (2002). Clinical, radiological and pathological examination of periocular dermoid cysts: evidence of inflammation from an early age. Eye, 16, 507-512.
  • Abu-Romman, A., Scholand, K. K., Govindarajan, G et al. (2024). Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing. IOVS, 65 (5), 21.
  • Avcı N, Gümüş F, Özgermen B, Sağlam M (2024). A review of surgical cases of newborn calves. TJVR, 8 (2), 89-94.
  • Badanes Z, Ledbetter EC (2019). Ocular dermoids in dogs: A retrospective study, Vet Ophthalmol, 22, 760-766.
  • Barkyoumb SD, Leipold HW (1984). Nature and cause of bilateral ocular dermoids in Hereford cattle. Vet Pathol, 21, 316-324.
  • Barrantes Murillo DF, Rissi DR, Wiener DJ, Negrão Watanabe TT (2025). Feline dermoid cyst: Retrospective case series and literature review. Vet Pathol, 62 (3), 293-299.
  • Bekele T, Bhokre AP, Mekonnen B, Tesfaye W, Alemu B et al. (2014). Ocular dermoid in crossbred calf-A case report. Ethiop Vet J, 18, 105-108.
  • Castro JR, Hendrix DV, Van Amstel SR (2006). Ocular dermoids in cattle: a case report and review. AABP, 40, 8-12.
  • Cathelin A, Augsburger AS, Anne J et al. (2022). Ocular dermoids in 13 cats: a multicentre retrospective study. JFMS, 24, 745-753.
  • Gelatt KN (2014). Essentials of Veterinary Ophthalmology. 3rd rev edn. Gainesville: FL, USA.
  • Michelet D, Brasher C, Kaddour HB et al. (2017). Postoperative complications following neonatal and infant surgery: common events and predictive factors. Anaesthesia Critical Care & Pain Medicine, 36 (3), 163-169.
  • Kaushik AK, Kandavel H, Nalpathamkalam T, Pasman Y (2021). Bovine neonate is deficient in innate immunity at birth. Mol Immunol. 133, 101–109.
  • Khatun N, Bhaduri A, Debbarma S, Dewan SVP (2018). Ocular dermoid cyst in a calf and its surgical management. JEZS, 6, 433-34.
  • Kiliç N, Toplu N, Epikmen ET (2012). Surgical treatment of corneal large dermoid in a simmental calf. ASVS, 40, 1-5.
  • Morgan J, Curtis Shaw G, Weisman J, Cecere, T, Carvallo-Chaigneau FR (2025). Bilateral intraocular choristoma in a 2-day-old foal. JVDI, 10406387251324997.
  • Mosbah E, Awadin WF, Abass M (2022). A Survey on Congenital Head Malformations in Calves. JAVS, 7, 72-79.
  • Okur DT (2021). Dystocia due to dicephalus in a cow. Bozok Vet Sci, 2 (1), 4–5.
  • Pigatto JA, Cargnin LS, Melo AP et al. (2025). Epidemiological findings of ocular dermoid in dogs and cats: 50 cases (2007-2024). Pesq Vet, 45, e07509.
  • Pigatto JAT, Torikachvili M, Seibel MP et al. (2024). Conjunctival dermoid in a cat: case report. Arq Bras Med Vet Zootec 76 (06), e13200.
  • Sarrafzadeh-Rezaei F, Farshid AA, Saifzadeh S (2007). Congenital ocular dermoid cyst in a river buffalo (Bubalus bubalis) calf. J Vet Med, 54, 51-54.
  • Abdelfattah E, Fausak E, Maier G (2025). Failure of Passive Immune Transfer in Neonatal Beef Calves: A Scoping Review. Animals, 15 (14), 2072.
  • Shuleshko OO, Zhorina LV, Lieshchova MO (2023). Histopathology of the ocular dermoid in a bull of the Ukrainian grey breed (clinical case). Theor Appl Vet Med, 11(4), 22-26.
  • Singh KP (2015). Surgical correction of ocular dermoids in six dogs. Indian J Canine Pract, 7 (1).
  • Sosa E, Giannitti F, Macías-Rioseco M et al. (2025). Congenital neoplasms in cattle: A literature review and multi-institutional case series. JVDI, 10406387251324512.
  • Verma A, Sangwan V, Bansal N et al. (2022). A rare case of dermoid cyst associated with parotid gland in a male buffalo calf. Large Anim Rev, 28, 307-310.
  • Zhu J, Lan X, Mo K et al. (2024). Deficiency of SECTM1 impairs corneal wound healing in aging. Aging Cell, 23 (10), e14247.
Toplam 26 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Veteriner Cerrahi
Bölüm Araştırma Makalesi
Yazarlar

Taner Arslan 0009-0001-4222-3718

Çağlar Özkalıpçı 0009-0000-9402-5679

Sıtkıcan Okur 0000-0003-2620-897X

Latif Emrah Yanmaz 0000-0001-5890-8271

Mümin Gökhan Şenocak 0000-0002-8855-8847

Ayşe Gölgeli Bedir 0000-0002-9798-8638

Ferda Turgut 0000-0003-2956-7548

Yakup Kocaman 0000-0002-3580-7782

İsmail Bolat 0000-0003-1398-7046

Ömer Tarık Orhun 0000-0003-4184-8879

Metin Kiliçlioğlu 0000-0001-9055-2164

Gönderilme Tarihi 25 Haziran 2025
Kabul Tarihi 4 Kasım 2025
Erken Görünüm Tarihi 30 Kasım 2025
Yayımlanma Tarihi 30 Kasım 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 36 Sayı: 3

Kaynak Göster

APA Arslan, T., Özkalıpçı, Ç., Okur, S., … Yanmaz, L. E. (2025). Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves. Van Veterinary Journal, 36(3), 199-204. https://doi.org/10.36483/vanvetj.1727292
AMA Arslan T, Özkalıpçı Ç, Okur S, vd. Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves. Van Vet J. Kasım 2025;36(3):199-204. doi:10.36483/vanvetj.1727292
Chicago Arslan, Taner, Çağlar Özkalıpçı, Sıtkıcan Okur, Latif Emrah Yanmaz, Mümin Gökhan Şenocak, Ayşe Gölgeli Bedir, Ferda Turgut, vd. “Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves”. Van Veterinary Journal 36, sy. 3 (Kasım 2025): 199-204. https://doi.org/10.36483/vanvetj.1727292.
EndNote Arslan T, Özkalıpçı Ç, Okur S, Yanmaz LE, Şenocak MG, Gölgeli Bedir A, Turgut F, Kocaman Y, Bolat İ, Orhun ÖT, Kiliçlioğlu M (01 Kasım 2025) Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves. Van Veterinary Journal 36 3 199–204.
IEEE T. Arslan vd., “Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves”, Van Vet J, c. 36, sy. 3, ss. 199–204, 2025, doi: 10.36483/vanvetj.1727292.
ISNAD Arslan, Taner vd. “Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves”. Van Veterinary Journal 36/3 (Kasım2025), 199-204. https://doi.org/10.36483/vanvetj.1727292.
JAMA Arslan T, Özkalıpçı Ç, Okur S, Yanmaz LE, Şenocak MG, Gölgeli Bedir A, Turgut F, Kocaman Y, Bolat İ, Orhun ÖT, Kiliçlioğlu M. Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves. Van Vet J. 2025;36:199–204.
MLA Arslan, Taner vd. “Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves”. Van Veterinary Journal, c. 36, sy. 3, 2025, ss. 199-04, doi:10.36483/vanvetj.1727292.
Vancouver Arslan T, Özkalıpçı Ç, Okur S, Yanmaz LE, Şenocak MG, Gölgeli Bedir A, vd. Retrospective Study on Surgical Outcomes of Congenital Cystic Dermoids in 17 Calves. Van Vet J. 2025;36(3):199-204.

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