İki Güvercin Sürüsünde Spontanöz Tüberküloz Vakaları

Öz

Bu çalışmada, Erciyes Üniversitesi Veteriner Fakültesi Patoloji Anabilim Dalı’na nekropsi amacıyla getirilen 2 yaşlı dişi kaya-cami güvercini ve 4 aylık 2 adet evcil taklacı güvercinde tüberküloz olgusu tanımlandı. Makroskobik incelemede, kaya güvercininde kaşektik tablo ile birlikte akciğer kesitlerinde toplu iğne başı büyüklüğünde sarımtırak renkte birkaç nodül görüldü. Taklacı güvercinlerin bir tanesinin sağ kanat altında gri-sarımtırak renkte 1 x 1.5 x 0.8 cm ebatlarında, karaciğer yüzeyinde ve barsakta jejunum üzerinde 0.5-1 mm’den 1 cm’ye kadar değişen büyüklükte, kursağa yakın 0.3 x 0.8 cm’lik gri-sarımtırak renkte nodüllerin varlığı dikkati çekti. Diğer taklacı güvercinde ise akciğerde 1 x 1.2 x 0.5 cm ve karaciğerde 0.5 x 0.7 x 0.6 cm ebatlarında gri-sarımtırak renkte nodüler yapılar görüldü. Histopatolojik incelemede bu nodüller lezyonların homojen eozinofilik renkte kazeifikasyon nekrozu olduğu, bunların çevresinde çok çekirdekli dev hücreleri, epiteloid histiyositler, histiyosit, lenfosit ve en dışta da fibröz bir kapsülden oluşan tipik tüberküllerden oluşan tüberküloz lezyonları olduğu gözlendi. Yapılan Ziehl-Neelsen boyamasında kaya güvercininde tüberküloz basilleri gözlenmezken, taklacı güvercinlerin her ikisinde de tüberkül yapılarında çok sayıda yoğun kırmızı renkte küçük kümeler halinde tüberküloz basilleri tespit edildi. Etkenin zoonoz karakterde olması ve kontaminasyon riski nedeniyle olgu sunumu şeklinde değerlendirilmiştir.

Anahtar Kelimeler

• Güvercin,Histopatoloji,Tüberküloz

Spontaneous Tuberculosis Cases In Two Pigeon Flocks

Öz

In this study, a 2-year-old female rock pigeon and two 4-month-old tumbler domestic pigeon brought to Erciyes University, Faculty of Veterinary Medicine, Department of Pathology, for necropsy were diagnosed as tuberculosis. On the macroscopic examination, several nodules with yellowish colour were seen in the pulmonary sections as well as in the rock pigeon. The grey-yellowish nodules were found on the right wings (1 x 1.5 x 0.8 cm in size), the liver surface and the jejunum in the small intestine (with a size ranging from 0.5-1 mm to 1 cm) and near the craw (0.3 x 0.8 cm in size) of the one tumbler pigeon. In other, grey-yellowish nodular structures were seen in the lungs 1 x 1.2 x 0.5 cm and 0.5 x 0.7 x 0.6 cm in the liver. Histopathological examination showed that these lesions were tuberculous lesions consisting of homogeneous eosinophilic colourized casein necrosis, surrounding multi-nucleated giant cells, epithelioid histiocytes, histiocytes, lymphocytes and, most extensively, typical tubercles with a fibrous capsule. According to In the Ziehl-Neelsen staining, tuberculous bacillus was not observed in the tissue of rock pigeon, while tuberculous bacillus was found in a large number of dense red in tubercle structures in both of the tumbler pigeons. Because of the zoonotic nature of the agent and the risk of contamination, it was evaluated as a case report.

Anahtar Kelimeler

• Histopathology,Pigeon,Tuberculosis

Kaynakça

1. Referans1 Bougiouklis P, Brellou G, Fragkiadaki E, Iordanidis P, Vlemmas I, Georgopoulou I (2005). Outbreak of Avian Mycobacteriosis in a flock of two‐year‐old domestic pigeons (Columba livia f. domestica). Avian Dis., 49: 442‐445.
2. Referans2 Fulton RM, Thoen CO (2000). Tuberculosis. In. Diseases of Poultry, Ed: Saif YM, 11th Ed., 836‐844, Iowa State Press, Ames.
3. Referans3 Garcia A, LeClear C, Gaskin J (2001). Mycobacterium avium infection in an ostrich. (Struthio camelus). J Zoo Wildl Med., 32: 96‐100.
4. Referans4 Gerhold RW, Fischer JR (2005). Avian tuberculosis in a wild turkey. Avian Dis., 49(1): 164-166,.
5. Referans5 Gonzalez M, Rodriguez-Bertos A, Gimeno I, Flores JM, Pizarro M (2002). Outbreak of avian tuberculosis in 48-week-old commercial layer hen flock. Avian Dis., 46(4): 1055-1061.
6. Referans6 Hejlicek K, Treml F (1994). Epizootiology and pathogenesis of avian mycobacteriosis in domestic pigeons (Columba livia f. domestica). Vet. Med., 39(10): 615-624.
7. Referans7 Hsieh YC, Tsai KY, Wang CY, Hung CN, Tsai SS, Liu HJ (2009). Diagnosis of avian tuberculosis in Swinhoe's pheasants. Using conventional and molecular‐based techniques. Avian Dis., 53: 629‐ 33.
8. Referans8 Kriz P, Slaný M, Shitaye JE, Pavlík I (2010). Avian mycobacteriosis in humans remains a threat in the Czech Republic. Klin Mikrobiol Infekc Lek., 16(1): 10‐17.

9. Referans9 Lennox AM (2007) Mycobacteriosis in companion psittacine birds: a review. J. Avian Med Surg., 21:181-187.
10. Referans10 Möbius P, Lentzsch P, Moser I, Naumann L, Martin G, Köhler H (2006). Comparative macrorestriction and RFLP analysis of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis isolates from man, pig, and cattle. Vet Microbiol., 117: 284‐291.
11. Referans11 Oruç E, Bali AF (2004). Tuberculosis in a young ostrich. Veterinarium, 1: 23‐26.
12. Referans12 Özcan K, Beytut E, Tuzcu M (2001). Tuberculosis in geese (Anser anser) in Turkey. Avian Dis., 45: 755‐759.
13. Referans13 Singbeil BA, Bickford AA, Stoltz JH (1993). Isolation of Mycobacterium avium from ringneck pheasants (Phasianus colchicus). Avian Dis., 37: 612-615.
14. Referans14 Tell L, Woods L, Foley J, Needham M, Walker RA (2003). Model of avian mycobacteriosis: clinical and histopathologic findings in Japanese quail (Coturnix coturnix japonica) Intravenously Inoculated with Mycobacterium avium. Avian Dis., 47: 433‐443.
15. Referans15 Thoen CO, Karlson AG (1991). Tuberculosis. In, Diseases of Poultry, Ed; Calnek BW, Barnes HJC, Beard W, Reid MW, Yoder HW, 9th Ed., 172-185, Iowa State University Press, Ames.