Effects of Topical Terebinth Berry Oil and Different Experimental Mixtures on Wound Healing in Japanese Quails (Coturnix Coturnix Japonica)

Yıl 2017, Cilt: 28 Sayı: 2, 69 - 74, 20.08.2017

Nihat Şındak , Mustafa Barış Akgül Ali Gülaydın , Zelal Karakoç

Öz

The aim
of the presented study is to investigate the effects of terebinth oil and
different experimental mixtures used topically in wound healing in Japanese
quails. 42 days old 30 adult Japanese quail animals were used as live animal
materials. The animals were divided into 5 groups each of containing 6 animals.
Experimental scar involving skin and subcutaneous connective tissue of
approximately 2 cm in diameter with each grubus scalpel was created and treated
with the prepared mixtures. The injuries were monitored daily and measurements
were made with digital calipers during dressing changes. On days 3^th,
7^th, 10^th and 13^th after the wound was
created, biopsy specimens were taken from all groups to include intact tissue
from the wound area and histopathologically examined. The data obtained were
analyzed statistically. The group in which the earliest healing was formed was
group II, followed by group I, group III, group IV and control group,
respectively. Histological evaluations revealed that the epithelialization
process was observed in group I and group II in a shorter time than the other
groups. As a result of the study, it has been concluded scientifically that the
mixture of menengic oil conventionally used by the public and pomade containing
50% Centella asiatica extract has positive effects on wound healing in quails.

Anahtar Kelimeler

Japanese quail, Terebinth berry oil, Nitrofurazone, Rifamisin, Centella asiatica

Japon Bıldırcınlarında (Coturnix Coturnix Japonica) Topikal Olarak Uygulanan Menengiç Yağı ve Farklı Deneysel Karışımlarının Yara İyileşmesi Üzerine Etkileri

Öz

Bu
çalışmanın amacı; Japon bıldırcınlarında yara iyileşmesinde topikal kullanılan
menengiç yağı ve farklı deneysel karışımlarının etkilerini araştırmaktır.
Çalışmada hayvan materyalini 42 günlük, 30 adet ergin Japon bıldırcın
oluşturdu. Her grupta 6 adet hayvan olacak şekilde 5 gruba ayrıldı. Her gruba
bisturi ile yaklaşık 2 cm çapında deri ve deri altı bağ dokusunu kapsayan
deneysel yara oluşturuldu ve hazırlanan karışımlar ile tedavi uygulandı.
Yaralar günlük olarak izlendi ve pansuman değişimleri esnasında dijital kumpas
yardımı ile ölçümü yapıldı. Yara oluşturulan günden sonra 3., 7., 10. ve 13.
günlerde tüm gruplardan yara bölgesinden sağlam dokuyu da içine alacak şekilde
biyopsi örnekleri alındı ve histopatolojik olarak incelendi. Araştırmada elde edilen
veriler istatistiki olarak analiz edildi. En erken iyileşmenin şekillendiği
grubun, grup II olduğu ve sırasıyla bunu grup I, grup III, grup IV ve kontrol
grubunun takip ettiği saptandı. Histolojik değerlendirmelerde grup I ve grup II’ de
diğer gruplara göre epitelizasyon sürecinin daha kısa sürede izlendiği
saptandı. Çalışma sonucunda geleneksel olarak halk arasında kullanılan menengiç
yağının ve %50 oranında Centella asiatica
ekstratı içeren pomad karışımının bilimsel olarak bıldırcınlarda yara iyileşmesi
üzerine olumlu etkilerinin olduğu kanaatine varıldı.

Anahtar Kelimeler

Japon bıldırcını, Menengiç yağı, Nitrofurazon, Rifamisin, Centella asiatica

Kaynakça

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