Yıl 2019, Cilt 10 , Sayı 2, Sayfalar 91 - 105 2019-08-21

VACCINE ADJUVANTS and THEIR UNDESIRABLE EFFECTS
AŞI ADJUVANLARI ve İSTENMEYEN ETKİLERİ

Buket Gül [1] , Begüm Yurdakök Dikmen [2]


One of the most effective methods for preventive medicine is vaccination. Ideal veterinary vaccines are expected have long life and high bioavailability, as well as least or none side effects. For these purposes, vaccine adjuvants are used to increase the immunogenity and enhance their effects. However, the adjuvants used in vaccines have generally known side effects. In this review, general information on vaccine adjuvants and possible toxic effects of adjuvants used in veterinary vaccines are summarized.


Koruyucu hekimlik uygulamaları içerisinde en etkin yöntemlerden biri aşılamadır. İdeal veteriner aşısından beklenenler; uzun ömürlü ve biyoyararlanımı yüksek olması, bunun yanında yan etki oluşturmamasıdır. Bu amaçla verildikleri antijeninin immünojenitesini arttıran ve güçlendiren maddeler olan aşı adjuvanları kullanılmaktadır. Ancak aşı adjuvanlarının genel olarak bilinen bazı yan etkileri vardır. Bu derlemede aşı adjuvanları hakkında genel bilgi verilmiş olup, veteriner aşılarda kullanılan adjuvanların olası toksik etkilerinden bahsedilmiştir.


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Birincil Dil tr
Konular Veterinerlik
Bölüm Derleme
Yazarlar

Orcid: 0000-0001-6584-8916
Yazar: Buket Gül (Sorumlu Yazar)
Kurum: ANKARA ÜNİVERSİTESİ

Orcid: 0000-0002-0385-3602
Yazar: Begüm Yurdakök Dikmen
Ülke: Turkey


Teşekkür Makale Ankara Üniversitesi Veteriner Fakültesi intörn bitirme ödevinin bir kısmını kapsamaktadır. Değerlendirme ve katkılarından dolayı Doğukan KAYA’ ya teşekkür ederiz.
Tarihler

Yayımlanma Tarihi : 21 Ağustos 2019

APA Gül, B , Yurdakök Dikmen, B . (2019). AŞI ADJUVANLARI ve İSTENMEYEN ETKİLERİ. Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni , 10 (2) , 91-105 . Retrieved from https://dergipark.org.tr/tr/pub/vetfarmatoksbulten/issue/47597/589723